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SAUCHINONE

Product Name: SAUCHINONE
CAS No.: 177931-17-8
Chemical Name: SAUCHINONE
Synonyms: AI300896;AI3-00896;AI3 00896;SAUCHINONE;Sauchinone-RM;Sauchinone >=98% (HPLC);Sauchinone, 98%, from Saururus chinensis (Lour. ) Baill;(5aR,7R,8S,8aR,14aS,14bR)-5a,6,7,8,8a,14b-Hexahydro-7,8-dimethyl-5H-Benzo[kl]bis[1,3]dioxolo[4,5-b:4′,5′-g]xanthen-5-one;(5aR,7R,8S,8aR,14aS,14bR)-7,8-Dimethyl-5a,6,7,8,8a,14b-hexahydro- 5H-benzo[kl]bis[1,3]dioxolo[4,5-b:4',5'-g]xanthen-5-one;(5aα,7α,8β,8aβ,14aS*,14bβ)-5a,6,7,8,8a,14b-Hexahydro-7,8-dimethyl-5H-benzo[kl]bis[1,3]dioxolo[4,5-b:4′,5′-g]xanthen-5-one
CBNumber: CB0821863
Molecular Formula: C20H20O6
Formula Weight: 356.37
MOL File: 177931-17-8.mol

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SAUCHINONE Property

Melting point:: 224-226℃
Boiling point:: 498.1±45.0 °C(Predicted)
Density: 1.43±0.1 g/cm3 (20 ºC 760 Torr)
storage temp.: 2-8°C
solubility: DMSO: soluble5mg/mL, clear (warmed)
form: powder
color: white to beige

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Safety

Safety Statements: 24/25
WGK Germany: 3
HS Code: 29329990

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0783
Product name: Sauchinone
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $144
Updated: 2025/07/31

Sigma-Aldrich

Product number: SML0783
Product name: Sauchinone
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $376
Updated: 2025/07/31

Cayman Chemical

Product number: 19577
Product name: Sauchinone
Purity: ≥98%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 19577
Product name: Sauchinone
Purity: ≥98%
Packaging: 5mg
Price: $109
Updated: 2024/03/01

Cayman Chemical

Product number: 19577
Product name: Sauchinone
Purity: ≥98%
Packaging: 10mg
Price: $199
Updated: 2024/03/01

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SAUCHINONE Chemical Properties,Usage,Production

Chemical Properties

Yellow crystalline powder, easily soluble in methanol and ethyl acetate, derived from Saururus chinensis.

Uses

Sauchinone is a lignan first isolated from the aerial parts of S. chinensis, a plant used in Asian medicine for its anti-inflammatory, anti-angiogenic, and anti-nociceptive activities. Sauchinone has numerous effects on isolated cells, including blocking NF-κB activation in LPS-stimulated macrophages, inducing heme oxygenase-1 transcription in endothelial cells, and attenuating oxidative-stress-induced damage in myoblasts. Sauchinone is extensively metabolized in vivo, but intraperitoneal administration significantly reduces myocardial infarct size induced by ischemia/reperfusion in mice.

Biological Activity

Sauchinone is an anti-inflammatory and antioxidant lignan isolated from Saururus chinensis a medical plant used for the treatment of fever, jaundice, oedema and inflammatory disease in oriental folk medicine. Sauchinone inhibits LPS-inducible iNOS (NOS II), TNF-α and COX-2 expression in macrophages through suppression of IKBα phosphorylation. It appears th at sauchinone protects against myocardial ischemia/reperfusion injury by inhibition of p28 phosphorylation.

SAUCHINONE Preparation Products And Raw materials

Raw materials

Preparation Products

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SAUCHINONE Suppliers

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View Lastest Price from SAUCHINONE manufacturers

Shanghai Standard Technology Co., Ltd.

Product: Sauchinone 177931-17-8
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2019-12-02

Career Henan Chemical Co

Product: SAUCHINONE 177931-17-8
Price: US $1.00/kg
Min. Order: 1g
Purity: 99%
Supply Ability: 100KG
Release date: 2018-12-24

177931-17-8, SAUCHINONERelated Search:

Carboxyatractyloside 3-N-OXALYL-L-2,3-DIAMINOPROPANOICACID Cornuside Alpinetin KAEMPFEROL-3-O-RUTINOSIDE SHANZHISIDE METHYL ESTER spicatosideB Complanatoside A Maslinic acid 7,8-Dihydroxycoumarin ARTEMISININ MORIN Cephalomannine Notoginsenoside R1 Sanggenon C dendrobine Evodiamine MONOCROTALINE

(5aR,7R,8S,8aR,14aS,14bR)-5a,6,7,8,8a,14b-Hexahydro-7,8-dimethyl-5H-Benzo[kl]bis[1,3]dioxolo[4,5-b:4′,5′-g]xanthen-5-one

(5aα,7α,8β,8aβ,14aS*,14bβ)-5a,6,7,8,8a,14b-Hexahydro-7,8-dimethyl-5H-benzo[kl]bis[1,3]dioxolo[4,5-b:4′,5′-g]xanthen-5-one

Sauchinone, 98%, from Saururus chinensis (Lour. ) Baill

SAUCHINONE

(5aR,7R,8S,8aR,14aS,14bR)-7,8-Dimethyl-5a,6,7,8,8a,14b-hexahydro- 5H-benzo[kl]bis[1,3]dioxolo[4,5-b:4',5'-g]xanthen-5-one

5H-Benzo[kl]bis[1,3]dioxolo[4,5-b:4',5'-g]xanthen-5-one, 5a,6,7,8,8a,14b-hexahydro-7,8-dimethyl-, (5aR,7R,8S,8aR,14aS,14bR)-

Sauchinone >=98% (HPLC)

AI3 00896

AI300896

AI3-00896

(5aR,5a1R,7R,8S,8aR,14aS)-7,8-Dimethyl-5a,5a1,6,7,8,8a-hexahydro-5H-benzo[kl]bis([1,3]dioxolo)[4,5-b:4',5'-g]xanthen-5-one

Sauchinone-RM

177931-17-8

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract