(1R,3R)-Methyl 1-(benzo[d][1,3]dioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate hydrochloride
- Product Name
- (1R,3R)-Methyl 1-(benzo[d][1,3]dioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate hydrochloride
- CAS No.
- 171752-68-4
- Chemical Name
- (1R,3R)-Methyl 1-(benzo[d][1,3]dioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate hydrochloride
- Synonyms
- methyl (1R,3R)-1-(1,3-benzodioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate,hydrochloride;Methyl (1R,3R)-1-(benzo[d][1,3]dioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate hydrochloride;TDF-DA-M1;Tadalafile N-2;CHEMPACIFIC 51475;Tetrahydrocarbaline;Aliskiren Impurity 65;Tadalafil Impurity 1 HCl;Tadalafil Impurity 22 HCl;Tadalafil Impurity 16 HCl
- CBNumber
- CB0840958
- Molecular Formula
- C20H19ClN2O4
- Formula Weight
- 386.82886
- MOL File
- 171752-68-4.mol
(1R,3R)-Methyl 1-(benzo[d][1,3]dioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate hydrochloride Property
- Melting point:
- 239-241 °C
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- DMSO (Slightly, Sonicated), Methanol (Slightly)
- form
- Solid
- color
- Off-White to Pale Yellow
- Stability:
- Hygroscopic
- InChI
- InChI=1/C20H18N2O4.ClH/c1-24-20(23)15-9-13-12-4-2-3-5-14(12)21-19(13)18(22-15)11-6-7-16-17(8-11)26-10-25-16;/h2-8,15,18,21-22H,9-10H2,1H3;1H/t15-,18-;/s3
- InChIKey
- ROYJOKDTCKPQHK-QHWQFTOMNA-N
- SMILES
- C12[C@@H](C3=CC=C4OCOC4=C3)N[C@H](CC=1C1C(=CC=CC=1)N2)C(OC)=O.Cl |&1:1,12,r|
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 7843CS
- Product name
- Methyl(1R,3R)-1-(1,3-benzodioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate;hydrochloride
- Packaging
- 5g
- Price
- $76
- Updated
- 2021/12/16
- Product number
- APN0000858
- Product name
- (1R,3R)-1,2,3,4-TETRAHYDRO-1-(3,4-METHYLENEDIOXYPH ENYL)-9H-PYRIDO[3,4-B]INDOLE-3-CARBOXYLIC ACID METHYL ESTER HYDROCHLORIDE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $496.53
- Updated
- 2021/12/16
- Product number
- A594987
- Product name
- (1R,3R)-Methyl1-(benzo[d][1,3]dioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylatehydrochloride
- Purity
- 98%
- Packaging
- 100g
- Price
- $114
- Updated
- 2021/12/16
- Product number
- A1472715
- Product name
- (1R,3R)-Methyl1-(benzo[d][1,3]dioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylatehydrochloride
- Purity
- 97%+(HPLC)
- Packaging
- 100g
- Price
- $114
- Updated
- 2021/12/16
- Product number
- CD11233784
- Product name
- (1R,3R)-Methyl1-(benzo[d][1,3]dioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylatehydrochloride
- Purity
- 98%
- Packaging
- 100g
- Price
- $128
- Updated
- 2021/12/16
(1R,3R)-Methyl 1-(benzo[d][1,3]dioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate hydrochloride Chemical Properties,Usage,Production
Preparation
D-tryptophan methyl ester hydrochloride and piperonal chloride dissolved in redistilled tetrahydrofuran and then added trifluoroacetic acid. Stir the reaction at 30 ° C for 10 h under the protection of nitrogen. Add sodium triacetoxyborohydride and continue the reaction for 3 hours. After the reaction is monitored by a TLC plate, the reaction solution is concentrated to about 10 mL, deionized water is added, and extracted with ethyl acetate twice. Saturated sodium chloride was washed twice, and dried under reduced pressure to obtain (1R,3R)-Methyl 1-(benzo[d][1,3]dioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate hydrochloride. The yield was 86.95%, the purity was 98.76%.
(1R,3R)-Methyl 1-(benzo[d][1,3]dioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
(1R,3R)-Methyl 1-(benzo[d][1,3]dioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate hydrochloride Suppliers
- Tel
- 0531-88065293 13287783460
- Fax
- 0531-88065293
- 3166282224@qq.com
- Country
- China
- ProdList
- 29
- Advantage
- 58
- Tel
- 0531-87586188 13046003282
- Fax
- 0531-87586188
- 3473674613@qq.com
- Country
- China
- ProdList
- 54
- Advantage
- 58
- Tel
- 0917-18691729 18691729963
- 2553382659@qq.com
- Country
- China
- ProdList
- 4752
- Advantage
- 58
- Tel
- 18064208139
- 2912268575@qq.com
- Country
- China
- ProdList
- 1335
- Advantage
- 58
- Tel
- 13053322091 13053322091
- admin@mopaikeji.com
- Country
- China
- ProdList
- 10970
- Advantage
- 58
- Tel
- 0531-58595315 13864187945
- 415834789@qq.com
- Country
- China
- ProdList
- 94
- Advantage
- 58
- Tel
- 18367470722
- 2885785763@qq.com
- Country
- China
- ProdList
- 3670
- Advantage
- 58
- Tel
- 13220585822 13220585822
- 1256200339@qq.com
- Country
- China
- ProdList
- 35
- Advantage
- 58
- Tel
- 0573-85285100 18627885956
- Fax
- 0573-85285100
- isenchem@163.com
- Country
- China
- ProdList
- 9492
- Advantage
- 66
- Tel
- 400-6009262 16621234537
- Fax
- 021-64823266
- zhangsn@titansci.com
- Country
- China
- ProdList
- 14113
- Advantage
- 59
- Tel
- 025-83697070
- Fax
- +86-25-83453306
- info@chemlin.com.cn
- Country
- China
- ProdList
- 18086
- Advantage
- 64
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
- Country
- China
- ProdList
- 42982
- Advantage
- 64
- Tel
- 025-52643182 13914798241
- Fax
- 025-52643182
- zhoulq@chemipioneer.com.cn
- Country
- China
- ProdList
- 76
- Advantage
- 62
- Tel
- 0531-58897003 15550412551
- Fax
- 0531-58897003
- market@jnchsd.com
- Country
- China
- ProdList
- 217
- Advantage
- 62
- Tel
- 021-61551611 13296011611
- Fax
- +86 21-50676805
- contact@trustwe.com
- Country
- China
- ProdList
- 9900
- Advantage
- 58
- Tel
- +86-28-85122536 85324413
- Fax
- +86-28-85326443
- market@astatech.cn
- Country
- China
- ProdList
- 8033
- Advantage
- 55
- Tel
- 27-81302488 18007166089
- Fax
- 027-81302088
- info@dkybpc.com
- Country
- China
- ProdList
- 2024
- Advantage
- 58
- Tel
- 15722085254
- Fax
- 022-26358246
- phytochemical@126.com
- Country
- China
- ProdList
- 813
- Advantage
- 55
- Tel
- 400-1647117 15221909166
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 41438
- Advantage
- 60
- Tel
- 021-60345187 13671753212
- Fax
- 021-34702061
- lzz841106@aliyun.com
- Country
- China
- ProdList
- 10287
- Advantage
- 55
- Tel
- 0531-0531-82929600 18615510361
- Fax
- 053182921652
- sale@rousechem.com
- Country
- China
- ProdList
- 175
- Advantage
- 58
- Tel
- 021-64609169 18901607656
- Fax
- 021-64609160
- greensnown@163.com
- Country
- China
- ProdList
- 9911
- Advantage
- 50
- Tel
- 13598610367
- Fax
- QQ:2468833170
- 2841375912@qq.com
- Country
- China
- ProdList
- 2760
- Advantage
- 52
- Tel
- 025-57018978 18251899859
- Fax
- 025-57018008
- sales@chalf-pharm.com
- Country
- China
- ProdList
- 5917
- Advantage
- 50
- Tel
- 531-88883606 15688880361
- Fax
- +86-531-69950228 QQ839101288 QQ2793626495
- sales@jnrxchem.com
- Country
- China
- ProdList
- 111
- Advantage
- 55
- Tel
- 027-027-59207879 18140587686
- Fax
- QQ:1972026995
- kf@3600chem.com
- Country
- China
- ProdList
- 4697
- Advantage
- 55
- Tel
- 025-58362220 15250997978
- Fax
- 025-58362220
- 1511893459@qq.com
- Country
- China
- ProdList
- 7772
- Advantage
- 55
- Tel
- 18068075658
- Fax
- -
- sales@chempioneer.com
- Country
- China
- ProdList
- 1811
- Advantage
- 58
- Tel
- 021-58088081 Q2816483246
- Fax
- QQ3382968513
- hailey@shsendpharm.com
- Country
- China
- ProdList
- 3139
- Advantage
- 55
- Tel
- +86 (10) 6333-0989
- Fax
- +86 (10) 8072-7398
- pppwmh@126.com
- Country
- China
- ProdList
- 212
- Advantage
- 55
- Tel
- +86 (531) 8099-2215
- Fax
- +86 (531) 8099-2215
- putubio@outlook.com
- Country
- China
- ProdList
- 1261
- Advantage
- 55
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
- ProdList
- 27322
- Advantage
- 60
- Tel
- 02781293128
- orders@biochemsafebuy.com
- Country
- China
- ProdList
- 9934
- Advantage
- 55
- Tel
- T:15050866711
- Fax
- QQ:2677337387
- wanglin.chen@radiant-pharma.com
- Country
- China
- ProdList
- 466
- Advantage
- 60
- Tel
- 021-2022843681 15618226720
- Fax
- +86-21-51601218
- chaolaichem@foxmail.com
- Country
- China
- ProdList
- 9242
- Advantage
- 58
- Tel
- 0371-0371-55629727 13323845623
- Fax
- 037155629727
- 2885676761@qq.com
- Country
- China
- ProdList
- 9859
- Advantage
- 58
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131980
- Advantage
- 58
- Tel
- 13127280945
- 285424065@qq.com
- Country
- China
- ProdList
- 9980
- Advantage
- 55
- Tel
- 028-028-64159575 13096309087
- Fax
- QQ3213375147
- anna@enlaibio.com
- Country
- China
- ProdList
- 2348
- Advantage
- 55
- Tel
- 531-82812892
- Fax
- 0531-82812892
- sunshinepharm0531@163.com
- Country
- China
- ProdList
- 68
- Advantage
- 58
- Tel
- 0531-58897070 15254140813
- Fax
- 0531-58897046
- market@jnchsd.com
- Country
- China
- ProdList
- 216
- Advantage
- 58
- Tel
- 571-85586718 +8613336195806
- Fax
- +86-571-85864795
- sales@capotchem.com
- Country
- China
- ProdList
- 29797
- Advantage
- 60
- Tel
- 025-66113011 18112977050
- Fax
- 02557626880
- sales01@aikonchem.com
- Country
- China
- ProdList
- 16028
- Advantage
- 58
- Tel
- 027-87466105 15377573527
- 2678564200@qq.com
- Country
- China
- ProdList
- 17997
- Advantage
- 58
- Tel
- 0531-58897066 13605407322
- Fax
- 0531-58897093
- shenyun@jnchsd.com
- Country
- China
- ProdList
- 202
- Advantage
- 58
- Tel
- 17368696818
- Country
- China
- ProdList
- 1986
- Advantage
- 58
- Tel
- 021-60345187 13917602471
- Fax
- 021-60345187
- lzz841106@aliyun.com
- Country
- China
- ProdList
- 9907
- Advantage
- 58
- Tel
- 400-8210725 18016230971
- Fax
- 021-58955996
- malulu@leyan.com
- Country
- China
- ProdList
- 24971
- Advantage
- 58
- Tel
- 0371-0371-55051623 18137891487
- Fax
- QQ:2853979817
- 2853979817@qq.com
- Country
- China
- ProdList
- 9843
- Advantage
- 58
- Tel
- 027-51831887 15337167856
- Fax
- 027-51837635 QQ1165326703
- hubeixinyuanshun@163.com
- Country
- China
- ProdList
- 10305
- Advantage
- 58
View Lastest Price from (1R,3R)-Methyl 1-(benzo[d][1,3]dioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate hydrochloride manufacturers
- Product
- 1,2,3,4-TETRAHYDRO-1-(3,4-METHYLENEDIOXYPH ENYL) 171752-68-4
- Price
- US $450.00-400.00/kg
- Min. Order
- 100kg
- Purity
- 99.99%
- Supply Ability
- 100Tons
- Release date
- 2023-03-17
- Product
- Tadalafil intermediate 171752-68-4
- Price
- US $20.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 2000kg
- Release date
- 2024-05-13
- Product
- Tadalafil intermediate 171752-68-4
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 6000KG
- Release date
- 2024-01-24