5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile

Product Name: 5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile
CAS No.: 330792-70-6
Chemical Name: 5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile
Synonyms: IbrutinibN-3;IbrutinibIntermediate4;Ibrutinib intermediate3;Zanubrutinib Impurity 8;Zanubrutinib impurity-20;Ibrutinib intermediates N-3;Zanubrutinib Related Compound 6;3-AMino-4-cyano-5-(4-phenoxyphenyl)pyrazole;3-Amino-5-(4-phenoxyphenyl)pyrazole-4-carbonitrile;3-amino-5-(4-phenoxyphenyl)-1H-Pyrazole-4-carbonitrile
CBNumber: CB62604963
Molecular Formula: C16H12N4O
Formula Weight: 276.29
MOL File: 330792-70-6.mol

More

Less

5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile Property

Boiling point:: 585.3±50.0 °C(Predicted)
Density: 1.37±0.1 g/cm3(Predicted)
refractive index: 1.699
Flash point:: 307.8℃
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: DMSO (Slightly)
pka: 10.83±0.50(Predicted)
InChI: InChI=1S/C16H12N4O/c17-10-14-15(19-20-16(14)18)11-6-8-13(9-7-11)21-12-4-2-1-3-5-12/h1-9H,(H3,18,19,20)
InChIKey: HNIMEQCLCNSCGH-UHFFFAOYSA-N
SMILES: N1C(C2=CC=C(OC3=CC=CC=C3)C=C2)=C(C#N)C(N)=N1
LogP: 3.25298

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

TRC

Product number: A603990
Product name: 3-Amino-4-cyano-5-(4-phenoxyphenyl)pyrazole
Packaging: 100mg
Price: $165
Updated: 2021/12/16

TRC

Product number: A603990
Product name: 3-Amino-4-cyano-5-(4-phenoxyphenyl)pyrazole
Packaging: 1g
Price: $1320
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0390612
Product name: 5-AMINO-3-(4-PHENOXYPHENYL)-1H-PYRAZOLE-4-CARBONITRILE
Purity: 95.00%
Packaging: 5MG
Price: $496.69
Updated: 2021/12/16

ChemScene

Product number: CS-M2596
Product name: 1H-Pyrazole-4-carbonitrile,3-amino-5-(4-phenoxyphenyl)-
Purity: 99.89%
Packaging: 10g
Price: $165
Updated: 2021/12/16

ChemScene

Product number: CS-M2596
Product name: 1H-Pyrazole-4-carbonitrile,3-amino-5-(4-phenoxyphenyl)-
Purity: 99.89%
Packaging: 25g
Price: $340
Updated: 2021/12/16

More

Less

5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile Chemical Properties,Usage,Production

Chemical Properties

Light yellow to off-white powder.

Uses

3-Amino-4-cyano-5-(4-phenoxyphenyl)pyrazole has been used as a reactant in the preparation of ring-fused pyrazole derivatives to be used a inhibitors of lymphocyte-specific kinase (Lck)

Application

5-amino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile is an intermediate of Ibrutinib (PCI-32765). it is a heterocyclic intermediate that typically used in the preparation of ACP-196, a selective second-generation BTK inhibitor.

5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile Suppliers

China 195 India 11 United Kingdom 1 United States 2 Global 209

Anhui nuoquan pharmaceutical co. LTD

Tel: 0556-5032870 15705561919
Fax: 0556-5032869
Email: sujuan.mei@nuoquanpharm.com
Country: China
ProdList: 96
Advantage: 55

Suzhou Sino Rare Chemical Co., Ltd.

Tel: 512-62857507
Email: sales@sinorarechem.com
Country: China
ProdList: 523
Advantage: 58

Foshan Junzheng Biotechnology Co., Ltd

Tel: 17813018085
Email: 181367029@qq.com
Country: China
ProdList: 62
Advantage: 58

Harway Pharma CO., LTD

Tel: 18254622207
Fax: 0546-5180666
Email: sales@harwaypharma.com
Country: China
ProdList: 76
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14103
Advantage: 59

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42958
Advantage: 64

Tongchuang Pharma(Suzhou). Co., Ltd.

Tel: 0512-63263366 18912765016
Fax: 0512-6326 3366
Email: tongtf110@sina.com
Country: China
ProdList: 976
Advantage: 62

Shanghai SynFarm Pharmaceutical Technology Co., Ltd.

Tel: 021-50793966 18917198199
Fax: +86-21-50793967
Email: info@synfarm.com
Country: China
ProdList: 280
Advantage: 58

Shanghai Topbiochem Technology Co., Ltd

Tel: +86-21-60341587
Fax: +86-21-61294319
Email: sales@topbiochem.com
Country: China
ProdList: 6175
Advantage: 58

More

Less

View Lastest Price from 5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile manufacturers

Shandong Huizhihan Supply Chain Co., Ltd

Product: 3-Amino-4-cyano-5-(4-phenoxyphenyl)pyrazole 330792-70-6
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20Tons
Release date: 2024-12-11

Shanghai Joiny Pharmaceutical Co.,LTD

Product: 3-Amino-4-cyano-5-(4-phenoxyphenyl)pyrazole 330792-70-6
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1000kg
Release date: 2024-12-05

Nanjing Fred Technology Co., Ltd

Product: 5-Amino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile 330792-70-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1 ton
Release date: 2023-12-28

330792-70-6, 5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrileRelated Search:

Vandetanib Vardenafil hydrochloride tert-butyl 4-(3-cyano-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-7-yl)piperidine-1-carboxylate Propanedinitrile, 2-[hydroxy(4-phenoxyphenyl)Methylene]- 1-Piperidinecarboxylic acid, 4-[3-(dimethylamino)-1-oxo-2-propen-1-yl]-, 1,1-dim (1R,3R)-Methyl-1,2,3,4-tetrahydro-2-chloroacetyl-1-(3,4-methylenedioxyphenyl)-9H-pyrido[3,4-b]indole-3-carboxylate ent-Tadalafil cis-ent-Tadalafil cis-Tadalafil (S)-1-Boc-3-hydroxypiperidine Propanedinitrile, 2-[Methoxy(4-phenoxyphenyl)Methylene]- Chloropretadalafil Trelagliptin succinate Tadalafil (1R,3R)-Methyl 1-(benzo[d][1,3]dioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate hydrochloride 5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyriMidin-4-ylaMine 3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine (R)-1-Boc-3-Hydroxypiperidine

5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile

3-amino-5-(4-phenoxyphenyl)-1H-Pyrazole-4-carbonitrile

3-AMino-4-cyano-5-(4-phenoxyphenyl)pyrazole

1H-Pyrazole-4-carbonitrile, 3-aMino-5-(4-phenoxyphenyl)-

3-Amino-5-(4-phenoxyphenyl)pyrazole-4-carbonitrile

Ibrutinib intermediates N-3

Zanubrutinib Related Compound 6

Zanubrutinib Impurity 8

Ibrutinib intermediate3

IbrutinibN-3

CAS330792-70-6 5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile

Zanubrutinib KSM-II : (4-isocyano-3-(4-phenoxyphenyl)-1H-pyrazol-5-amine)

IbrutinibIntermediate4

Zanubrutinib impurity-20

Zanubrutinib impurity-8 (3-Amino-4-cyano-5-(4-phenoxyphenyl)pyrazole

330792-70-6

330790-70-6

330792-70-6