5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile

Product Name: 5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile
CAS No.: 330792-70-6
Chemical Name: 5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile
Synonyms: IbrutinibN-3;IbrutinibIntermediate4;Ibrutinib intermediate3;Zanubrutinib Impurity 8;Zanubrutinib impurity-20;Ibrutinib intermediates N-3;Zanubrutinib Related Compound 6;3-AMino-4-cyano-5-(4-phenoxyphenyl)pyrazole;3-Amino-5-(4-phenoxyphenyl)pyrazole-4-carbonitrile;3-amino-5-(4-phenoxyphenyl)-1H-Pyrazole-4-carbonitrile
CBNumber: CB62604963
Molecular Formula: C16H12N4O
Formula Weight: 276.29
MOL File: 330792-70-6.mol

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5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile Property

Boiling point:: 585.3±50.0 °C(Predicted)
Density: 1.37±0.1 g/cm3(Predicted)
refractive index: 1.699
Flash point:: 307.8℃
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: DMSO (Slightly)
pka: 10.83±0.50(Predicted)
InChI: InChI=1S/C16H12N4O/c17-10-14-15(19-20-16(14)18)11-6-8-13(9-7-11)21-12-4-2-1-3-5-12/h1-9H,(H3,18,19,20)
InChIKey: HNIMEQCLCNSCGH-UHFFFAOYSA-N
SMILES: N1C(C2=CC=C(OC3=CC=CC=C3)C=C2)=C(C#N)C(N)=N1
LogP: 3.25298

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: A603990
Product name: 3-Amino-4-cyano-5-(4-phenoxyphenyl)pyrazole
Packaging: 100mg
Price: $165
Updated: 2021/12/16

TRC

Product number: A603990
Product name: 3-Amino-4-cyano-5-(4-phenoxyphenyl)pyrazole
Packaging: 1g
Price: $1320
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0390612
Product name: 5-AMINO-3-(4-PHENOXYPHENYL)-1H-PYRAZOLE-4-CARBONITRILE
Purity: 95.00%
Packaging: 5MG
Price: $496.69
Updated: 2021/12/16

ChemScene

Product number: CS-M2596
Product name: 1H-Pyrazole-4-carbonitrile,3-amino-5-(4-phenoxyphenyl)-
Purity: 99.89%
Packaging: 10g
Price: $165
Updated: 2021/12/16

ChemScene

Product number: CS-M2596
Product name: 1H-Pyrazole-4-carbonitrile,3-amino-5-(4-phenoxyphenyl)-
Purity: 99.89%
Packaging: 25g
Price: $340
Updated: 2021/12/16

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5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile Chemical Properties,Usage,Production

Chemical Properties

Light yellow to off-white powder.

Uses

3-Amino-4-cyano-5-(4-phenoxyphenyl)pyrazole has been used as a reactant in the preparation of ring-fused pyrazole derivatives to be used a inhibitors of lymphocyte-specific kinase (Lck)

Application

5-amino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile is an intermediate of Ibrutinib (PCI-32765). it is a heterocyclic intermediate that typically used in the preparation of ACP-196, a selective second-generation BTK inhibitor.

5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

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5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile Suppliers

China 187 India 10 United Kingdom 1 United States 2 Global 200

Anhui nuoquan pharmaceutical co. LTD

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Shanghai SynFarm Pharmaceutical Technology Co., Ltd.

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Shanghai Topbiochem Technology Co., Ltd

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View Lastest Price from 5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile manufacturers

Nanjing Fred Technology Co., Ltd

Product: 5-Amino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile 330792-70-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1 ton
Release date: 2023-12-28

Shaanxi Dideu New Materials Co. Ltd

Product: 5-amino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile 330792-70-6
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10000KGS
Release date: 2024-11-13

Henan Fengda Chemical Co., Ltd

Product: 5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile 330792-70-6
Price: US $10.00-3.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-29

330792-70-6, 5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrileRelated Search:

Vandetanib Vardenafil hydrochloride tert-butyl 4-(3-cyano-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-7-yl)piperidine-1-carboxylate Propanedinitrile, 2-[hydroxy(4-phenoxyphenyl)Methylene]- 1-Piperidinecarboxylic acid, 4-[3-(dimethylamino)-1-oxo-2-propen-1-yl]-, 1,1-dim (1R,3R)-Methyl-1,2,3,4-tetrahydro-2-chloroacetyl-1-(3,4-methylenedioxyphenyl)-9H-pyrido[3,4-b]indole-3-carboxylate ent-Tadalafil cis-ent-Tadalafil cis-Tadalafil (S)-1-Boc-3-hydroxypiperidine Propanedinitrile, 2-[Methoxy(4-phenoxyphenyl)Methylene]- Chloropretadalafil Trelagliptin succinate Tadalafil (1R,3R)-Methyl 1-(benzo[d][1,3]dioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate hydrochloride 5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyriMidin-4-ylaMine 3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine (R)-1-Boc-3-Hydroxypiperidine

5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile

3-amino-5-(4-phenoxyphenyl)-1H-Pyrazole-4-carbonitrile

3-AMino-4-cyano-5-(4-phenoxyphenyl)pyrazole

1H-Pyrazole-4-carbonitrile, 3-aMino-5-(4-phenoxyphenyl)-

3-Amino-5-(4-phenoxyphenyl)pyrazole-4-carbonitrile

Ibrutinib intermediates N-3

Zanubrutinib Related Compound 6

Zanubrutinib Impurity 8

Ibrutinib intermediate3

IbrutinibN-3

CAS330792-70-6 5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile

Zanubrutinib KSM-II : (4-isocyano-3-(4-phenoxyphenyl)-1H-pyrazol-5-amine)

IbrutinibIntermediate4

Zanubrutinib impurity-20

Zanubrutinib impurity-8 (3-Amino-4-cyano-5-(4-phenoxyphenyl)pyrazole

330792-70-6

330790-70-6

330792-70-6