2,3-Dihydro-1,4-dioxino[2,3-b]pyridine
- Product Name
- 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine
- CAS No.
- 129421-32-5
- Chemical Name
- 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine
- Synonyms
- 2,3-Dihydro-1,4-Dioxino[2,3-b];2H,3H-[1,4]dioxino[2,3-b]pyridine;2,3-Dihydro-1,4-dioxino[2,3-b]pyridine;1,4-Dioxino[2,3-b]pyridine, 2,3-dihydro;Benzoicacid,3-bromo-8-methoxy-,hydrazide;5-Benzofuransulfonylchloride,2,8-dihydro-;2,3-Dihydro-1,4-dioxino[2,3-b]pyridine?New;1,4-Dioxino[2,3-b]pyridine,2,3-dihydro-(9CI);2,3-Dihydro-1,4-dioxino[2,3-b]pyridine ISO 9001：2015 REACH
- CBNumber
- CB0854858
- Molecular Formula
- C7H7NO2
- Formula Weight
- 137.14
- MOL File
- 129421-32-5.mol
2,3-Dihydro-1,4-dioxino[2,3-b]pyridine Property
- Boiling point:
- 234°C
- Density
- 1.229
- Flash point:
- 84°C
- storage temp.
- Sealed in dry,Room Temperature
- form
- solid
- pka
- 4.93±0.20(Predicted)
- color
- Off-white
- InChI
- InChI=1S/C7H7NO2/c1-2-6-7(8-3-1)10-5-4-9-6/h1-3H,4-5H2
- InChIKey
- QWQZJEXJTYAPGE-UHFFFAOYSA-N
- SMILES
- C12OCCOC1=CC=CN=2
Safety
- HazardClass
- IRRITANT
- HS Code
- 2934999090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- ADE000017
- Product name
- 2,3-Dihydro-[1,4]dioxino[2,3-b]pyridine
- Purity
- Aldrich
- Packaging
- 1g
- Price
- $817
- Updated
- 2025/07/31
- Product number
- D453978
- Product name
- 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- D453978
- Product name
- 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine
- Packaging
- 100mg
- Price
- $240
- Updated
- 2021/12/16
- Product number
- FD106499
- Product name
- 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine
- Packaging
- 250mg
- Price
- $100
- Updated
- 2021/12/16
- Product number
- 4H56-1-0PT
- Product name
- 2,3-Dihydro[1,4]dioxino[2,3-b]pyridine
- Purity
- 97%
- Packaging
- 1g
- Price
- $144
- Updated
- 2021/12/16
2,3-Dihydro-1,4-dioxino[2,3-b]pyridine Chemical Properties,Usage,Production
Synthesis
16867-04-2
106-93-4
129421-32-5
a-1) Synthesis of 2,3-dihydro-[1,4]dioxohexa[2,3-b]pyridine 2,3-Dihydroxypyridine (2.22 g, 20.0 mmol) was dissolved in N,N-dimethylformamide (100 mL) and potassium carbonate (5.52 g, 40.0 mmol) was added at room temperature. After stirring for 5 min, 1,2-dibromoethane (2.6 mL, 30.0 mmol) was added slowly and dropwise at the same temperature. The reaction mixture was heated to 90 °C and the reaction was stirred overnight. Upon completion of the reaction, the mixture was cooled to room temperature and filtered to remove the insoluble salt. The filtrate was concentrated under reduced pressure to remove the solvent and the resulting residue was dissolved in ethyl acetate. The suspension was filtered, the filter cake was washed with ethyl acetate, the filtrates were combined and concentrated again under reduced pressure to give 2,3-dihydro-1,4-dioxo[2,3-b]pyridine (157 mg, 5.7% yield) as a colorless oil. 1H-NMR (CDCl3) δ: 4.26-4.28 (2H, m), 4.42-4.44 (2H, m), 6.94 (1H, dd, J = 5.6, 7.6 Hz), 7.28 (1H, dd, J = 1.2, 7.6 Hz), 7.69 (1H, dd, J = 1.2, 5.6 Hz).
References
[1] Patent: US2010/280013, 2010, A1. Location in patent: Page/Page column 49
[2] Patent: WO2015/42397, 2015, A1. Location in patent: Paragraph 000788
2,3-Dihydro-1,4-dioxino[2,3-b]pyridine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine manufacturers
- Product
- 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine 129421-32-5
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.0% min
- Supply Ability
- 100 tons min
- Release date
- 2021-05-13
- Product
- 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine 129421-32-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1000KGS
- Release date
- 2019-12-17