ChemicalBook > CAS DataBase List > 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine

2,3-Dihydro-1,4-dioxino[2,3-b]pyridine

Product Name: 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine
CAS No.: 129421-32-5
Chemical Name: 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine
Synonyms: 2,3-Dihydro-1,4-Dioxino[2,3-b];2H,3H-[1,4]dioxino[2,3-b]pyridine;2,3-Dihydro-1,4-dioxino[2,3-b]pyridine;1,4-Dioxino[2,3-b]pyridine, 2,3-dihydro;Benzoicacid,3-bromo-8-methoxy-,hydrazide;5-Benzofuransulfonylchloride,2,8-dihydro-;2,3-Dihydro-1,4-dioxino[2,3-b]pyridine?New;1,4-Dioxino[2,3-b]pyridine,2,3-dihydro-(9CI);2,3-Dihydro-1,4-dioxino[2,3-b]pyridine ISO 9001：2015 REACH
CBNumber: CB0854858
Molecular Formula: C7H7NO2
Formula Weight: 137.14
MOL File: 129421-32-5.mol

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2,3-Dihydro-1,4-dioxino[2,3-b]pyridine Property

Boiling point:: 234°C
Density: 1.229
Flash point:: 84°C
storage temp.: Sealed in dry,Room Temperature
form: solid
pka: 4.93±0.20(Predicted)
color: Off-white
InChI: InChI=1S/C7H7NO2/c1-2-6-7(8-3-1)10-5-4-9-6/h1-3H,4-5H2
InChIKey: QWQZJEXJTYAPGE-UHFFFAOYSA-N
SMILES: C12OCCOC1=CC=CN=2

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Safety

HazardClass: IRRITANT
HS Code: 2934999090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: ADE000017
Product name: 2,3-Dihydro-[1,4]dioxino[2,3-b]pyridine
Purity: Aldrich
Packaging: 1g
Price: $817
Updated: 2025/07/31

TRC

Product number: D453978
Product name: 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine
Packaging: 10mg
Price: $45
Updated: 2021/12/16

TRC

Product number: D453978
Product name: 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine
Packaging: 100mg
Price: $240
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD106499
Product name: 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine
Packaging: 1g
Price: $250
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD106499
Product name: 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine
Packaging: 250mg
Price: $100
Updated: 2021/12/16

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2,3-Dihydro-1,4-dioxino[2,3-b]pyridine Chemical Properties,Usage,Production

Synthesis

16867-04-2

106-93-4

129421-32-5

a-1) Synthesis of 2,3-dihydro-[1,4]dioxohexa[2,3-b]pyridine 2,3-Dihydroxypyridine (2.22 g, 20.0 mmol) was dissolved in N,N-dimethylformamide (100 mL) and potassium carbonate (5.52 g, 40.0 mmol) was added at room temperature. After stirring for 5 min, 1,2-dibromoethane (2.6 mL, 30.0 mmol) was added slowly and dropwise at the same temperature. The reaction mixture was heated to 90 °C and the reaction was stirred overnight. Upon completion of the reaction, the mixture was cooled to room temperature and filtered to remove the insoluble salt. The filtrate was concentrated under reduced pressure to remove the solvent and the resulting residue was dissolved in ethyl acetate. The suspension was filtered, the filter cake was washed with ethyl acetate, the filtrates were combined and concentrated again under reduced pressure to give 2,3-dihydro-1,4-dioxo[2,3-b]pyridine (157 mg, 5.7% yield) as a colorless oil. 1H-NMR (CDCl3) δ: 4.26-4.28 (2H, m), 4.42-4.44 (2H, m), 6.94 (1H, dd, J = 5.6, 7.6 Hz), 7.28 (1H, dd, J = 1.2, 7.6 Hz), 7.69 (1H, dd, J = 1.2, 5.6 Hz).

References

[1] Patent: US2010/280013, 2010, A1. Location in patent: Page/Page column 49
[2] Patent: WO2015/42397, 2015, A1. Location in patent: Paragraph 000788

2,3-Dihydro-1,4-dioxino[2,3-b]pyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine 129421-32-5
Price: US $1.10/g
Min. Order: 1g
Purity: 99.0% min
Supply Ability: 100 tons min
Release date: 2021-05-13

Career Henan Chemical Co

Product: 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine 129421-32-5
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1000KGS
Release date: 2019-12-17

129421-32-5, 2,3-Dihydro-1,4-dioxino[2,3-b]pyridineRelated Search:

Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate Sodium phosphate monobasic DIPIPERIDINOMETHANE Pyridine 4,5,6,7-Tetrahydrothieno[3,2-c]pyridine 2,6-Lutidine Piperidine 2,3-Dihydroxypyridine 2,3-Dimethoxypyridine 3-Cyano-4,6-dimethyl-2-hydroxypyridine 2,3-dihydro-[1,4]dioxino[2,3-b]pyridine-6-carbaldehyde 2,3-DIHYDRO[1,4]DIOXINO[2,3-C]PYRIDINE-7-CARBALDEHYDE 2,3-dihydro-[1,4]dioxino[2,3-b]pyridine-7-carbaldehyde 3-Pyridinol,2-ethoxy-(9CI) 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine

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1,4-Dioxino[2,3-b]pyridine,2,3-dihydro-(9CI)

2H,3H-[1,4]dioxino[2,3-b]pyridine

2,3-Dihydro-1,4-dioxino[2,3-b]pyridine ISO 9001：2015 REACH

Benzoicacid,3-bromo-8-methoxy-,hydrazide

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2,3-Dihydro-1,4-dioxino[2,3-b]pyridine?New

129421-32-5

PYRIDINE

Heterocycle-Pyridine series