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2,3-Dihydro-1,4-dioxino[2,3-b]pyridine

Product Name
2,3-Dihydro-1,4-dioxino[2,3-b]pyridine
CAS No.
129421-32-5
Chemical Name
2,3-Dihydro-1,4-dioxino[2,3-b]pyridine
Synonyms
2,3-Dihydro-1,4-Dioxino[2,3-b];2H,3H-[1,4]dioxino[2,3-b]pyridine;2,3-Dihydro-1,4-dioxino[2,3-b]pyridine;1,4-Dioxino[2,3-b]pyridine, 2,3-dihydro;Benzoicacid,3-bromo-8-methoxy-,hydrazide;5-Benzofuransulfonylchloride,2,8-dihydro-;2,3-Dihydro-1,4-dioxino[2,3-b]pyridine?New;1,4-Dioxino[2,3-b]pyridine,2,3-dihydro-(9CI);2,3-Dihydro-1,4-dioxino[2,3-b]pyridine ISO 9001：2015 REACH
CBNumber
CB0854858
Molecular Formula
C7H7NO2
Formula Weight
137.14
MOL File
129421-32-5.mol
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2,3-Dihydro-1,4-dioxino[2,3-b]pyridine Property

Boiling point:
234°C
Density 
1.229
Flash point:
84°C
storage temp. 
Sealed in dry,Room Temperature
form 
solid
pka
4.93±0.20(Predicted)
color 
Off-white
InChI
InChI=1S/C7H7NO2/c1-2-6-7(8-3-1)10-5-4-9-6/h1-3H,4-5H2
InChIKey
QWQZJEXJTYAPGE-UHFFFAOYSA-N
SMILES
C12OCCOC1=CC=CN=2
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Safety

HazardClass 
IRRITANT
HS Code 
2934999090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
ADE000017
Product name
2,3-Dihydro-[1,4]dioxino[2,3-b]pyridine
Purity
Aldrich
Packaging
1g
Price
$817
Updated
2025/07/31
TRC
Product number
D453978
Product name
2,3-Dihydro-1,4-dioxino[2,3-b]pyridine
Packaging
10mg
Price
$45
Updated
2021/12/16
TRC
Product number
D453978
Product name
2,3-Dihydro-1,4-dioxino[2,3-b]pyridine
Packaging
100mg
Price
$240
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD106499
Product name
2,3-Dihydro-1,4-dioxino[2,3-b]pyridine
Packaging
1g
Price
$250
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD106499
Product name
2,3-Dihydro-1,4-dioxino[2,3-b]pyridine
Packaging
250mg
Price
$100
Updated
2021/12/16
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2,3-Dihydro-1,4-dioxino[2,3-b]pyridine Chemical Properties,Usage,Production

Synthesis

16867-04-2

106-93-4

129421-32-5

a-1) Synthesis of 2,3-dihydro-[1,4]dioxohexa[2,3-b]pyridine 2,3-Dihydroxypyridine (2.22 g, 20.0 mmol) was dissolved in N,N-dimethylformamide (100 mL) and potassium carbonate (5.52 g, 40.0 mmol) was added at room temperature. After stirring for 5 min, 1,2-dibromoethane (2.6 mL, 30.0 mmol) was added slowly and dropwise at the same temperature. The reaction mixture was heated to 90 °C and the reaction was stirred overnight. Upon completion of the reaction, the mixture was cooled to room temperature and filtered to remove the insoluble salt. The filtrate was concentrated under reduced pressure to remove the solvent and the resulting residue was dissolved in ethyl acetate. The suspension was filtered, the filter cake was washed with ethyl acetate, the filtrates were combined and concentrated again under reduced pressure to give 2,3-dihydro-1,4-dioxo[2,3-b]pyridine (157 mg, 5.7% yield) as a colorless oil. 1H-NMR (CDCl3) δ: 4.26-4.28 (2H, m), 4.42-4.44 (2H, m), 6.94 (1H, dd, J = 5.6, 7.6 Hz), 7.28 (1H, dd, J = 1.2, 7.6 Hz), 7.69 (1H, dd, J = 1.2, 5.6 Hz).

References

[1] Patent: US2010/280013, 2010, A1. Location in patent: Page/Page column 49
[2] Patent: WO2015/42397, 2015, A1. Location in patent: Paragraph 000788

2,3-Dihydro-1,4-dioxino[2,3-b]pyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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2,3-Dihydro-1,4-dioxino[2,3-b]pyridine Suppliers

China 96 Europe 1 Germany 2 India 1 United Kingdom 2 United States 11 Global 113
NovoChemy Ltd.
Tel
021-31261262/ 49 (0)17662837245
Fax
(0)21-33250524
Email
sales@novochemy.com
Country
Germany
ProdList
6328
Advantage
58
Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71
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View Lastest Price from 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
2,3-Dihydro-1,4-dioxino[2,3-b]pyridine 129421-32-5
Price
US $1.10/g
Min. Order
1g
Purity
99.0% min
Supply Ability
100 tons min
Release date
2021-05-13
Career Henan Chemical Co
Product
2,3-Dihydro-1,4-dioxino[2,3-b]pyridine 129421-32-5
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000KGS
Release date
2019-12-17

129421-32-5, 2,3-Dihydro-1,4-dioxino[2,3-b]pyridineRelated Search:

Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate Sodium phosphate monobasic DIPIPERIDINOMETHANE Pyridine 4,5,6,7-Tetrahydrothieno[3,2-c]pyridine 2,6-Lutidine Piperidine 2,3-Dihydroxypyridine 2,3-Dimethoxypyridine 3-Cyano-4,6-dimethyl-2-hydroxypyridine 2,3-dihydro-[1,4]dioxino[2,3-b]pyridine-6-carbaldehyde 2,3-DIHYDRO[1,4]DIOXINO[2,3-C]PYRIDINE-7-CARBALDEHYDE 2,3-dihydro-[1,4]dioxino[2,3-b]pyridine-7-carbaldehyde 3-Pyridinol,2-ethoxy-(9CI) 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine

  • 1,4-Dioxino[2,3-b]pyridine, 2,3-dihydro
  • 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine
  • 2,3-Dihydro-1,4-Dioxino[2,3-b]
  • 1,4-Dioxino[2,3-b]pyridine,2,3-dihydro-(9CI)
  • 2H,3H-[1,4]dioxino[2,3-b]pyridine
  • 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine ISO 9001：2015 REACH
  • Benzoicacid,3-bromo-8-methoxy-,hydrazide
  • 5-Benzofuransulfonylchloride,2,8-dihydro-
  • 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine?New
  • 129421-32-5
  • PYRIDINE
  • Heterocycle-Pyridine series