ChemicalBook > CAS DataBase List > Indisulam

Indisulam

Product Name
Indisulam
CAS No.
165668-41-7
Chemical Name
Indisulam
Synonyms
D04522;E-7070;ER-35744;INDISULAM;IndisulaM (E7070);INDISULAM iMpurity;E7070;ER-35744;D04522;Indisulam >=98% (HPLC);IndisulaM (E7070) (ER-35744);N-(3-Chloro-1H-indol-7-yl)-1,4-benzenedisulfonamide
CBNumber
CB11011305
Molecular Formula
C14H12ClN3O4S2
Formula Weight
385.85
MOL File
165668-41-7.mol
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Indisulam Property

Melting point:
242-243 °C (decomp)(Solv: ethanol (64-17-5); water (7732-18-5))
Boiling point:
668.9±65.0 °C(Predicted)
Density 
1.663±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
DMSO : 100 mg/mL (259.17 mM; Need ultrasonic)
form 
powder
pka
8.14±0.30(Predicted)
color 
white to beige
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML1225
Product name
Indisulam
Purity
≥98% (HPLC)
Packaging
5MG
Price
$142
Updated
2023/06/20
Sigma-Aldrich
Product number
SML1225
Product name
Indisulam
Purity
≥98% (HPLC)
Packaging
25MG
Price
$564
Updated
2023/06/20
Cayman Chemical
Product number
22759
Product name
Indisulam
Purity
≥98%
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
22759
Product name
Indisulam
Purity
≥98%
Packaging
5mg
Price
$116
Updated
2024/03/01
Cayman Chemical
Product number
22759
Product name
Indisulam
Purity
≥98%
Packaging
10mg
Price
$214
Updated
2024/03/01
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Indisulam Chemical Properties,Usage,Production

Definition

ChEBI: Indisulam is a chloroindole that is 3-chloro-1H-indole substituted by a [(4-sulfamoylphenyl)sulfonyl]nitrilo group at position 7. It is a carbonic anhydrase inhibitor and a potential anti-cancer agent currently in clinical development. It has a role as an EC 4.2.1.1 (carbonic anhydrase) inhibitor and an antineoplastic agent. It is a chloroindole, a sulfonamide and an organochlorine compound.

Biochem/physiol Actions

Indisulam is a carbonic anhydrase inibitor and Antitumor CDK inhibitor. Indisulam targets the G1 phase of the cell cycle by depleting cyclin E. inducing p53 and p21, and inhibiting CDK2, causing a blockade in the G1/S transition.

storage

Store at -20°C

Indisulam Preparation Products And Raw materials

Raw materials

Preparation Products

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Indisulam Suppliers

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View Lastest Price from Indisulam manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
Indisulam 165668-41-7
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1Ton
Release date
2022-10-13
Career Henan Chemical Co
Product
Indisulam 165668-41-7
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
200kg
Release date
2020-01-13

165668-41-7, IndisulamRelated Search:

Chlorantraniliprole Benzenesulfonamide Sulfanilamide Amlodipine Besylate (S)-Amlodipine Phenylacetyl chloride Diphenyl chlorophosphate Hydrochlorothiazide 2-CHLOROINDOLE 3-CHLORO-1H-INDOL-7-AMINE 7-Aminoindole Indisulam Difluorochloromethane

  • INDISULAM
  • 1,4-Benzenedisulfonamide, N-(3-chloro-1H-indol-7-yl)-
  • N-(3-Chloro-1H-indol-7-yl)-1,4-benzenedisulfonamide
  • E-7070
  • ER-35744
  • IndisulaM (E7070)
  • IndisulaM (E7070) (ER-35744)
  • N1-(3-Chloro-1H-indol-7-yl)benzene-1,4-disulfonamide
  • D04522
  • E7070;ER-35744;D04522
  • 1,4-Benzenedisulfonamide, N1-(3-chloro-1H-indol-7-yl)-
  • Indisulam >=98% (HPLC)
  • N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonamide
  • E-7070,Indisulam,Carbonic Anhydrase,Inhibitor,Carbonate dehydratase,E7070,inhibit
  • INDISULAM iMpurity
  • 165668-41-7
  • C14H12ClN3O4S2