Tectorigenin
- Product Name
- Tectorigenin
- CAS No.
- 548-77-6
- Chemical Name
- Tectorigenin
- Synonyms
- Tectrigenin;Tectorigenine;4',5,7-Trihydroxy-6-methoxyisoflavone;5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-methoxychromone;5,7-Dihydroxy-3-(4-hydroxy-phenyl)-6-methoxy-chromen-4-one;5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one;6-Methoxy-5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one;5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one;4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-;Tectorigenin 5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one
- CBNumber
- CB11040716
- Molecular Formula
- C16H12O6
- Formula Weight
- 300.26
- MOL File
- 548-77-6.mol
Tectorigenin Property
- Melting point:
- 225-226°
- Boiling point:
- 361.5°C (rough estimate)
- Density
- 1.512
- refractive index
- 1.4600 (estimate)
- storage temp.
- Sealed in dry,2-8°C
- solubility
- DMSO : 150 mg/mL (499.57 mM; Need ultrasonic and warming)
- form
- powder to crystal
- pka
- 6.49±0.20(Predicted)
- color
- White to Orange to Green
- BRN
- 305601
- InChI
- InChI=1S/C16H12O6/c1-21-16-11(18)6-12-13(15(16)20)14(19)10(7-22-12)8-2-4-9(17)5-3-8/h2-7,17-18,20H,1H3
- InChIKey
- OBBCRPUNCUPUOS-UHFFFAOYSA-N
- SMILES
- C1OC2=CC(O)=C(OC)C(O)=C2C(=O)C=1C1=CC=C(O)C=C1
- CAS DataBase Reference
- 548-77-6
Safety
- WGK Germany
- 3
- RTECS
- NR2400000
- HS Code
- 2932.99.6100
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330Rinse mouth.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- T3729
- Product name
- Tectorigenin
- Packaging
- 10MG
- Price
- $138
- Updated
- 2024/03/01
- Product number
- T3729
- Product name
- Tectorigenin
- Packaging
- 50MG
- Price
- $412
- Updated
- 2024/03/01
- Product number
- FT73920
- Product name
- Tectorigenin
- Packaging
- 100mg
- Price
- $500
- Updated
- 2021/12/16
- Product number
- PXT0001061
- Product name
- 4',5,7-TRIHYDROXY-6-METHOXYISOFLAVONE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $504.63
- Updated
- 2021/12/16
- Product number
- 100270
- Product name
- 5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $742
- Updated
- 2021/12/16
Tectorigenin Chemical Properties,Usage,Production
Description
Tectorigenin is an isoflavone that exists in numerous plant resources, and it is especially abundant in Belamcandae Rhizoma and Puerariae flos, which both have the effects of clearing away heat, removing toxic substances, relieving sore throat, and reducing swelling. As one of the most important active ingredients, the pharmacological effects of tectorigenin have been demonstrated by an increasing number of investigators. Due to its extensive pharmacological activities, including anticancer, antioxidation, hepatoprotection, anti-inflammation, etc., tectorigenin has received a large amount of attention[1].
Occurrence
Tectorigenin, a methoxy isoflavone with three hydroxyl groups, is chemically noted as 5,7-dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one. As a bioactive compound, tectorigenin is found in several plant species, most notably in the rhizomes of Belamcanda chinensis (L.) DC., a traditional Chinese medicine (TCM) named Belamcandae Rhizoma. The Iris family is the major source of tectorigenin, and many Iridaceous plants, such as Iris spuria L. (Calizona), Iris tectorum Maxim, Iris japonica Thunb., Iris dichotoma Pall., Iris germanica L., Iris unguicularis Poiret, Iris loczyi Kan., Iris kashmiriana Baker, Iris crocea Jacq. ex R. C. Foster, Iris ensata Thunb., Iris germanica L., Iris hungarica Waldst. et Kit., Iris confusa Sealy, and Iris pseudacorus L. contain abundant tectorigenin, so tectorigenin is also known as iris flavone. Tectorigenin also exists in some leguminous plants, such as the flowers of Pueraria lobata (Willd.) Ohwi, Pueraria thomsonii Benth., and Pueraria thunbergiana Benth. are also TCM called Puerariae Flos. Tectorigenin was isolated from the leaves of Dalbergia odorifera T. Chen, the heartwood of Dalbergia parviflora Roxb., and the roots of Euchresta formosana (Hayata) Ohwi as well. Moreover, some plants in other families also contain tectorigenin, including Codonopsis pilosula (Franch.) Nannf. (Campanulaceae), Morus alba L. (Moraceae), Viola hondoensis W. Becker et H. Boissieu. (Violaceae), and Eleocharis dulcis (Burm. f.) Trin. ex Hensch. (Cyperaceae)[1].
Uses
Tectorigenin is identified as an α-glucosidase inhibitors. Potent lactate dehydrogenase (LDH) inhibitor.
Definition
ChEBI: A methoxyisoflavone that is isoflavone substituted by a methoxy group at position 6 and hydroxy groups at positions 5, 7 and 4' respectively.
Synthesis Reference(s)
Synthetic Communications, 38, p. 525, 2008 DOI: 10.1080/00397910701796725
References
[1] Juan Rong. “Tectorigenin: A Review of Its Sources, Pharmacology, Toxicity, and Pharmacokinetics.” Molecules 28 15 (2023).
Tectorigenin Preparation Products And Raw materials
Raw materials
Preparation Products
Tectorigenin Suppliers
- Tel
- --
- Fax
- --
- sales@carbosynth.com
- Country
- United Kingdom
- ProdList
- 6005
- Advantage
- 58
View Lastest Price from Tectorigenin manufacturers
- Product
- Tectorigenin 548-77-6
- Price
- US $220.00/g
- Min. Order
- 1g
- Purity
- 98% HPLC
- Supply Ability
- 50kg
- Release date
- 2024-08-07
- Product
- Tectorigenin 548-77-6
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2019-11-01
- Product
- Tectorigenin 548-77-6
- Price
- US $1.00/kg
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2018-12-24