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ISOPIMPINELLIN

Product Name
ISOPIMPINELLIN
CAS No.
482-27-9
Chemical Name
ISOPIMPINELLIN
Synonyms
NSC 217988;NSC 401288;AKOS 243-24;Isoimpinellin;ISOPIMPINELLIN;DIMETHYLPSORALEN;ISOPIMPINELLIN(P);Isopimpinellin>Isopimpinellin-RM;Isopimpinellin (6CI)
CBNumber
CB6207988
Molecular Formula
C13H10O5
Formula Weight
246.22
MOL File
482-27-9.mol
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ISOPIMPINELLIN Property

Melting point:
150-151°C
Boiling point:
448.7±45.0 °C(Predicted)
Density 
1.352±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,2-8°C
solubility 
Soluble in acetone and chloroform;
form 
powder to crystal
color 
Light yellow to Yellow to Green
Water Solubility 
practically insoluble in water
λmax
268nm(MeOH)(lit.)
BRN 
262337
InChI
InChI=1S/C13H10O5/c1-15-10-7-3-4-9(14)18-12(7)13(16-2)11-8(10)5-6-17-11/h3-6H,1-2H3
InChIKey
DFMAXQKDIGCMTL-UHFFFAOYSA-N
SMILES
C1(=O)OC2=C(OC)C3OC=CC=3C(OC)=C2C=C1
LogP
1.407 (est)
CAS DataBase Reference
482-27-9(CAS DataBase Reference)
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Safety

Hazard Codes 
T+
Risk Statements 
20/21/22-28
Safety Statements 
22-36/37/39-45-36/37-28
RIDADR 
UN 2811 6.1 / PGII
WGK Germany 
3
RTECS 
LV1049200
HS Code 
2932202000
Hazardous Substances Data
482-27-9(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P262Do not get in eyes, on skin, or on clothing.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
61419
Product name
Isopimpinellin
Purity
analytical standard
Packaging
10mg
Price
$298
Updated
2022/05/15
TCI Chemical
Product number
I0861
Product name
Isopimpinellin
Purity
>98.0%(GC)
Packaging
10mg
Price
$247
Updated
2025/07/31
Usbiological
Product number
300493
Product name
Isopimpinellin
Packaging
20mg
Price
$490
Updated
2021/12/16
Usbiological
Product number
280356
Product name
Isopimpinellin
Packaging
50mg
Price
$1140
Updated
2021/12/16
TRC
Product number
I821950
Product name
Isopimpinellin
Packaging
250mg
Price
$1485
Updated
2021/12/16
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ISOPIMPINELLIN Chemical Properties,Usage,Production

Description

Psoralens are natural photoactivable compounds in plants and can cause phototoxic contact dermatitis. For example, Cachrys libanotis contains 5,8-dimethoxypsoralen.

Chemical Properties

Pale Yellow Solid

Uses

Antiviral, anti HIV

Uses

antineoplastic, antifungal, insect antifeedant

Definition

ChEBI: Isopimpinellin is a member of psoralens.

Hazard

A poison by ingestion.

Contact allergens

Psoralens are natural photoactivable compounds in plants and can cause phototoxic contact dermatitis. For example, Cachrys libanotis L., Apiaceae-Umbelliferae family, contains 5,8-dimethoxypsoralen.

Synthesis

14348-23-3

74-88-4

482-27-9

General procedure for the synthesis of 4,9-dimethoxyfuro[3,2-g]benzopyran-7-one (Isopimpinellin, 29) from the compound (CAS:14348-23-3) and iodomethane: To a solution of 200 mg (0.9 mmol) of compound 25 in anhydrous DMF (30 mL) was added K2CO3 (286 mg. 2.07 mmol) and CH3I (167 μL, 3.6 mmol). The reaction mixture was heated to reflux under argon protection; after 1 h of reaction, the mixture was poured into cold water (100 mL) and acidified with 1 M aqueous HCl. The product was extracted with ethyl acetate (3 x 50 mL), the organic layers were combined, and the solvent was removed by concentration under reduced pressure to give the crude product. The crude product was purified by column chromatography (eluent: ethyl acetate/hexane, 1:1). The fraction containing the target compound was collected, concentrated and dried to give 29 as a pale yellow powder (182 mg, 82% yield).

References

[1] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 2, p. 784 - 788

ISOPIMPINELLIN Preparation Products And Raw materials

Raw materials

Preparation Products

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ISOPIMPINELLIN Suppliers

Huzhou ZhanShu Biotechnology Co.,Ltd
Tel
0572-8889530 18167260939
Email
zsubio@163.com
Country
China
ProdList
392
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chembest Research Laboratories Limited
Tel
+86-21-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6003
Advantage
61
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18729
Advantage
57
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11705
Advantage
57
Aktin Chemicals, Inc.
Tel
86-28-85159085
Fax
86-28-85152372
Email
info@aktinchem.com
Country
China
ProdList
297
Advantage
62
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
sales@meilune.com
Country
China
ProdList
4747
Advantage
58
BioBioPha Co., Ltd.
Tel
0871-65217109 13211707573;
Fax
0871-65215563
Email
y.liu@mail.biobiopha.com
Country
China
ProdList
5653
Advantage
65
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View Lastest Price from ISOPIMPINELLIN manufacturers

Shanghai Standard Technology Co., Ltd.
Product
Isopimpinellin 482-27-9
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2019-10-29
Zhuozhou Wenxi import and Export Co., Ltd
Product
isopimpinellin 482-27-9
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-26
Career Henan Chemical Co
Product
ISOPIMPINELLIN 482-27-9
Price
US $2.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
10000kg
Release date
2018-08-10

482-27-9, ISOPIMPINELLINRelated Search:


  • 4,9-Dimethoxy-7H-furo[3,2-g]chromen-7-one
  • 4,9-Dimethoxy-furo[3,2-g]chromen-7-one
  • 5,8-Dimethoxy-6,7-furanocoumarin
  • 5,8-Dimethoxypsoralen
  • 5,8-Dimethoxypsoralene
  • 7H-Furo[3,2-g][1]benzopyran-7-one, 4,9-dimethoxy-
  • 7H-Furo[3,2-g][1]benzopyran-7-one,4,9-dimethoxy-
  • ISOPIMPINELLIN
  • DIMETHYLPSORALEN
  • 4,9-DIMETHOXYPSORALEN
  • 5,9-DIMETHOXYPSORALEN
  • AKOS 243-24
  • Isopimpinellin - Angelica archangelica (angelica)
  • 4,9-Dimethoxy-7H-furo[3,2-g][1]benzopyran-7-one
  • DIMETHYLPSORALEN hplc
  • ISOPIMPINELLIN WITH HPLC
  • 4,9-Dimethoxy-7H-furo[3,2-γ],[1]benzopyran-7-one
  • 4,9-Dimethoxy-furo[3,2-γ],chromen-7-one
  • Isoimpinellin
  • NSC 217988
  • NSC 401288
  • ISOPIMPINELLIN(P)
  • Isopimpinellin&gt
  • 4,9-Dimethoxyfuro[3,2-g]benzopyran-7-one
  • ISOPIMPINELLIN ISO 9001:2015 REACH
  • Isopimpinellin (6CI)
  • Isopimpinellin-RM
  • ISOPIMPINELLIN, 10 mM in DMSO
  • 482-27-9
  • Heterocyclic Compounds
  • Heterocycles
  • Coumarins