ChemicalBook > CAS DataBase List > Bupranolol
Bupranolol
- Product Name
- Bupranolol
- CAS No.
- 14556-46-8
- Chemical Name
- Bupranolol
- Synonyms
- Bupranol;Bupranolol;Ophtorenin;BRN 2272923;Bupranololum;KL 255Ophtorenin;B 1312; BRN 2272923; BUPRANOLOLUM; KL 255OPHTORENIN;1-(tert-Butylamino)-3-[(6-chloro-m-tolyl)oxy]-2-propanol;1-(tert-Butylamino)-3-(2-chloro-5-methylphenoxy)-2-propanol;(S)-1-(tert-Butylamino)-3-(2-chloro-5-methylphenoxy)-2-propanol
- CBNumber
- CB11118303
- Molecular Formula
- C14H22ClNO2
- Formula Weight
- 271.78
- MOL File
- 14556-46-8.mol
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Bupranolol Property
- Melting point:
- 71-74°C
- Boiling point:
- 396.3±42.0 °C(Predicted)
- Density
- 1.098±0.06 g/cm3(Predicted)
- storage temp.
- Hygroscopic, Refrigerator, Under Inert Atmosphere
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 13.82±0.20(Predicted)
- color
- White to Off-White
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N-Bromosuccinimide Price
TRC
- Product number
- B689650
- Product name
- Bupranolol
- Packaging
- 500mg
- Price
- $215
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- INB0000484
- Product name
- BUPRANOLOL
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $496.82
- Updated
- 2021/12/16
Medical Isotopes, Inc.
- Product number
- 44129
- Product name
- Bupranolol
- Packaging
- 5G
- Price
- $2400
- Updated
- 2021/12/16
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Bupranolol Chemical Properties,Usage,Production
Originator
Betadrenol,Pharma-Schwarz,W. Germany,1969
Uses
Bupranolol is an antagonist at the cardiostimulatory low-affinity state of b(1)-adrenoceptors and is known to treat hypertension and tachycardia.
Definition
ChEBI: Bupranolol is an aromatic ether.
Manufacturing Process
A mixture of 16.3 g of (2-chloro-5-methylphenyl)glycidic ether (from epichlorohydrin and 2-chloro-5-methylphenol) and 6.2 g of t-butylamine in 50 ml of ethanol is heated at reflux for 6 hours. The solvent is removed, the residue is washed with water and then extracted with benzene. The dried extract is evaporated to give 1-t-butylamino-3-(2-chloro-5-methylphenoxy)-2- propanol. Treatment of the free base in benzene solution with dry hydrogen chloride yields the hydrochloride salt.
Therapeutic Function
Antiarrhythmic
Bupranolol Preparation Products And Raw materials
Raw materials
Preparation Products
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14556-46-8, BupranololRelated Search:
AROTINOLOL
Acebutolol
Bupranolol
3-(2-chlorophenoxy)propan-1-amine
toliprolol
3-(3-METHYLPHENOXY)PROPAN-1-AMINE HYDROCHLORIDE
4-chloro-3-methoxytoluene
3-(tert-butylamino)-1-[(6-chloro-m-tolyl)oxy]propan-2-ol hydrochloride
[3-(2-CHLORO-PHENOXY)-PROPYL]-METHYL-AMINE
2-CHLORO-5-METHYLPHENOL
S-Bupranolol