Bupranolol

Product Name: Bupranolol
CAS No.: 14556-46-8
Chemical Name: Bupranolol
Synonyms: Bupranol;Bupranolol;Ophtorenin;BRN 2272923;Bupranololum;KL 255Ophtorenin;Bupranolol, 10 mM in DMSO;Bupranolol, beta adrenoceptor antagonist;B 1312; BRN 2272923; BUPRANOLOLUM; KL 255OPHTORENIN;1-(tert-Butylamino)-3-[(6-chloro-m-tolyl)oxy]-2-propanol
CBNumber: CB11118303
Molecular Formula: C14H22ClNO2
Formula Weight: 271.78
MOL File: 14556-46-8.mol

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Bupranolol Property

Melting point:: 71-74°C
Boiling point:: 396.3±42.0 °C(Predicted)
Density: 1.098±0.06 g/cm3(Predicted)
storage temp.: Hygroscopic, Refrigerator, Under Inert Atmosphere
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: 13.82±0.20(Predicted)
color: White to Off-White

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: B689650
Product name: Bupranolol
Packaging: 500mg
Price: $215
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: INB0000484
Product name: BUPRANOLOL
Purity: 95.00%
Packaging: 5MG
Price: $496.82
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 44129
Product name: Bupranolol
Packaging: 5G
Price: $2400
Updated: 2021/12/16

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Bupranolol Chemical Properties,Usage,Production

Originator

Betadrenol,Pharma-Schwarz,W. Germany,1969

Uses

Bupranolol is an antagonist at the cardiostimulatory low-affinity state of b(1)-adrenoceptors and is known to treat hypertension and tachycardia.

Definition

ChEBI: Bupranolol is an aromatic ether.

Manufacturing Process

A mixture of 16.3 g of (2-chloro-5-methylphenyl)glycidic ether (from epichlorohydrin and 2-chloro-5-methylphenol) and 6.2 g of t-butylamine in 50 ml of ethanol is heated at reflux for 6 hours. The solvent is removed, the residue is washed with water and then extracted with benzene. The dried extract is evaporated to give 1-t-butylamino-3-(2-chloro-5-methylphenoxy)-2- propanol. Treatment of the free base in benzene solution with dry hydrogen chloride yields the hydrochloride salt.

Therapeutic Function

Antiarrhythmic

Bupranolol Preparation Products And Raw materials

Raw materials

Preparation Products

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Bupranolol Suppliers

Canada 1 China 33 India 1 United Kingdom 1 United States 10 Global 46

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
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Chemsky（shanghai）International Co.,Ltd.

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Email: shchemsky@sina.com
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BOC Sciences

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Country: United States
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Hangzhou Sage Chemical Co., Ltd.

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Fax: Pls mail us for more information!
Email: info@sagechem.com
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AdooQ BioScience, LLC

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Fax: +1 (866) 333-9607
Email: info@adooq.com
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Chengdu Kamel Pharmaceutical Co., Ltd

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Shanghai EFE Biological Technology Co., Ltd.

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Shanghai YuanYe Biotechnology Co., Ltd.

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Tianjin Kailiqi Biotechnology Co., Ltd.

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Shenzhen Polymeri Biochemical Technology Co., Ltd.

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14556-46-8, BupranololRelated Search:

AROTINOLOL Acebutolol Bupranolol 3-(2-chlorophenoxy)propan-1-amine toliprolol 3-(3-METHYLPHENOXY)PROPAN-1-AMINE HYDROCHLORIDE 4-chloro-3-methoxytoluene 3-(tert-butylamino)-1-[(6-chloro-m-tolyl)oxy]propan-2-ol hydrochloride [3-(2-CHLORO-PHENOXY)-PROPYL]-METHYL-AMINE 2-CHLORO-5-METHYLPHENOL S-Bupranolol

(2S)-1-(tert-Butylamino)-3-(2-chloro-5-methylphenoxy)-2-propanol

(S)-1-(tert-Butylamino)-3-(2-chloro-5-methylphenoxy)-2-propanol

1-(tert-Butylamino)-3-(2-chloro-5-methylphenoxy)-2-propanol

1-(tert-Butylamino)-3-[(6-chloro-m-tolyl)oxy]-2-propanol

1-[(2-Chloro-5-methylphenyl)oxy]-3-[(1,1-dimethylethyl)amino]propan-2-ol

Bupranolol

2-Propanol, 1-(2-chloro-5-methylphenoxy)-3-[(1,1-dimethylethyl)amino]-

2-Propanol, 1-(tert-butylamino)-3-[(6-chloro-m-tolyl)oxy]- (8CI)

Bupranol

Ophtorenin

B 1312; BRN 2272923; BUPRANOLOLUM; KL 255OPHTORENIN

BRN 2272923

Bupranololum

KL 255Ophtorenin

non-selective,competitive,Adrenergic Receptor,Bupranolol,Inhibitor,intrinsic,sympathomimetic,active,Beta Receptor,inhibit,orally

Bupranolol, beta adrenoceptor antagonist

Bupranolol, 10 mM in DMSO

1-(tert-Butylamino)-3-(2-chloro-5-methylphenoxy)propan-2-ol

14556-46-8