Bupranolol

Product Name: Bupranolol
CAS No.: 14556-46-8
Chemical Name: Bupranolol
Synonyms: Bupranol;Bupranolol;Ophtorenin;BRN 2272923;Bupranololum;KL 255Ophtorenin;B 1312; BRN 2272923; BUPRANOLOLUM; KL 255OPHTORENIN;1-(tert-Butylamino)-3-[(6-chloro-m-tolyl)oxy]-2-propanol;1-(tert-Butylamino)-3-(2-chloro-5-methylphenoxy)-2-propanol;(S)-1-(tert-Butylamino)-3-(2-chloro-5-methylphenoxy)-2-propanol
CBNumber: CB11118303
Molecular Formula: C14H22ClNO2
Formula Weight: 271.78
MOL File: 14556-46-8.mol

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Bupranolol Property

Melting point:: 71-74°C
Boiling point:: 396.3±42.0 °C(Predicted)
Density: 1.098±0.06 g/cm3(Predicted)
storage temp.: Hygroscopic, Refrigerator, Under Inert Atmosphere
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: 13.82±0.20(Predicted)
color: White to Off-White

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: B689650
Product name: Bupranolol
Packaging: 500mg
Price: $215
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: INB0000484
Product name: BUPRANOLOL
Purity: 95.00%
Packaging: 5MG
Price: $496.82
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 44129
Product name: Bupranolol
Packaging: 5G
Price: $2400
Updated: 2021/12/16

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Bupranolol Chemical Properties,Usage,Production

Originator

Betadrenol,Pharma-Schwarz,W. Germany,1969

Uses

Bupranolol is an antagonist at the cardiostimulatory low-affinity state of b(1)-adrenoceptors and is known to treat hypertension and tachycardia.

Definition

ChEBI: Bupranolol is an aromatic ether.

Manufacturing Process

A mixture of 16.3 g of (2-chloro-5-methylphenyl)glycidic ether (from epichlorohydrin and 2-chloro-5-methylphenol) and 6.2 g of t-butylamine in 50 ml of ethanol is heated at reflux for 6 hours. The solvent is removed, the residue is washed with water and then extracted with benzene. The dried extract is evaporated to give 1-t-butylamino-3-(2-chloro-5-methylphenoxy)-2- propanol. Treatment of the free base in benzene solution with dry hydrogen chloride yields the hydrochloride salt.

Therapeutic Function

Antiarrhythmic

Bupranolol Preparation Products And Raw materials

Raw materials

Preparation Products

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Bupranolol Suppliers

Canada 1 China 24 India 1 United Kingdom 1 United States 8 Global 35

Toronto Research Chemicals

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Email: info@trc-canada.com
Country: Canada
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14556-46-8, BupranololRelated Search:

AROTINOLOL Acebutolol Bupranolol 3-(2-chlorophenoxy)propan-1-amine toliprolol 3-(3-METHYLPHENOXY)PROPAN-1-AMINE HYDROCHLORIDE 4-chloro-3-methoxytoluene 3-(tert-butylamino)-1-[(6-chloro-m-tolyl)oxy]propan-2-ol hydrochloride [3-(2-CHLORO-PHENOXY)-PROPYL]-METHYL-AMINE 2-CHLORO-5-METHYLPHENOL S-Bupranolol

(2S)-1-(tert-Butylamino)-3-(2-chloro-5-methylphenoxy)-2-propanol

(S)-1-(tert-Butylamino)-3-(2-chloro-5-methylphenoxy)-2-propanol

1-(tert-Butylamino)-3-(2-chloro-5-methylphenoxy)-2-propanol

1-(tert-Butylamino)-3-[(6-chloro-m-tolyl)oxy]-2-propanol

1-[(2-Chloro-5-methylphenyl)oxy]-3-[(1,1-dimethylethyl)amino]propan-2-ol

Bupranolol

2-Propanol, 1-(2-chloro-5-methylphenoxy)-3-[(1,1-dimethylethyl)amino]-

2-Propanol, 1-(tert-butylamino)-3-[(6-chloro-m-tolyl)oxy]- (8CI)

Bupranol

Ophtorenin

B 1312; BRN 2272923; BUPRANOLOLUM; KL 255OPHTORENIN

BRN 2272923

Bupranololum

KL 255Ophtorenin

non-selective,competitive,Adrenergic Receptor,Bupranolol,Inhibitor,intrinsic,sympathomimetic,active,Beta Receptor,inhibit,orally

14556-46-8