PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH
- Product Name
- PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH
- CAS No.
- 217082-60-5
- Chemical Name
- PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH
- Synonyms
- Pyr-apelin-13;[PYR1]-APELIN-13;(Glp1)-Apelin-13;[pGlu1]-Apelin-13;{Glp}-RPRLSHKGPMPF;PYR-RPRLSHKGPMPF-OH;3-Dimethyluric acid;[PE]APELIN-13, HUMAN, BOVINE;(GLP1)-APELIN-13, HUMAN, BOVINE;(PYR1)-APELIN-13 (HUMAN, BOVINE)
- CBNumber
- CB1113712
- Molecular Formula
- C69H108N22O16S
- Formula Weight
- 1533.8
- MOL File
- 217082-60-5.mol
PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH Property
- Density
- 1.51±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Store in freezer, under -20°C
- pka
- 3.56±0.10(Predicted)
- form
- Powder
- color
- White to off-white
- Water Solubility
- Soluble to 1 mg/ml in sterile water
- Sequence
- Pyr-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- J66114
- Product name
- [Glp1]-Apelin-13, human, bovine
- Packaging
- 0.5mg
- Price
- $69.7
- Updated
- 2021/12/16
- Product number
- J66114
- Product name
- [Glp1]-Apelin-13, human, bovine
- Packaging
- 1mg
- Price
- $94.3
- Updated
- 2021/12/16
- Product number
- 15590
- Product name
- (Glp1)-Apelin-13
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $109
- Updated
- 2021/12/16
- Product number
- 2420
- Product name
- [Pyr1]-Apelin-13
- Packaging
- 1
- Price
- $192
- Updated
- 2021/12/16
- Product number
- FP109298
- Product name
- (Pyr 1)-Apelin-13
- Packaging
- 2mg
- Price
- $273
- Updated
- 2021/12/16
PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH Chemical Properties,Usage,Production
Uses
The apelin gene encodes a pre-proprotein that is processed to generate bioactive peptides consisting of 36, 17, or 13 amino acids: apelin-36 , apelin-17, and apelin-13 , respectively. Apelin-13 is an endogenous ligand of the APJ receptor, activating this G protein-coupled receptor with an EC50 value of 0.37 nM. (Glp1)-Apelin-13 is a pyroglutamylated form of apelin-13, in that the N-terminal glutamine residue is cyclized to pyroglutamic acid. Like apelin-13, this compound is a potent APJ receptor agonist (EC50 = 0.30 nM). (Glp1)-Apelin-13 is the major apelin isoform in the plasma of healthy human subjects. It can have vasoconstrictor and antipyretic effects in vitro and in vivo.
Definition
ChEBI: P-Glu-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe is a thirteen-membered polypeptide consisting of p-Glu, Arg, Pro, Arg, Leu, Ser, His, Lys, Gly, Pro, Met, Pro and Phe residues joined in sequence. It has a role as an apoptosis inhibitor, a neuroprotective agent and a human metabolite. It is a tautomer of a [Pyr1]apelin-13(2+).
storage
Store at -20°C
PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH Preparation Products And Raw materials
Raw materials
Preparation Products
PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH Suppliers
- Tel
- --
- Fax
- --
- sales@carbosynth.com
- Country
- United Kingdom
- ProdList
- 6005
- Advantage
- 58
- Tel
- --
- Fax
- --
- customerservice@tocris.co.uk
- Country
- United Kingdom
- ProdList
- 5726
- Advantage
- 77
View Lastest Price from PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH manufacturers
- Product
- PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH 217082-60-5
- Price
- US $3.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2019-07-11