PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH

Product Name: PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH
CAS No.: 217082-60-5
Chemical Name: PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH
Synonyms: Pyr-apelin-13;[PYR1]-APELIN-13;(Glp1)-Apelin-13;[pGlu1]-Apelin-13;{Glp}-RPRLSHKGPMPF;PYR-RPRLSHKGPMPF-OH;3-Dimethyluric acid;[PE]APELIN-13, HUMAN, BOVINE;(GLP1)-APELIN-13, HUMAN, BOVINE;(PYR1)-APELIN-13 (HUMAN, BOVINE)
CBNumber: CB1113712
Molecular Formula: C69H108N22O16S
Formula Weight: 1533.8
MOL File: 217082-60-5.mol

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PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH Property

Density: 1.51±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Store in freezer, under -20°C
pka: 3.56±0.10(Predicted)
form: Powder
color: White to off-white
Water Solubility: Soluble to 1 mg/ml in sterile water
Sequence: Pyr-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Alfa Aesar

Product number: J66114
Product name: [Glp1]-Apelin-13, human, bovine
Packaging: 0.5mg
Price: $69.7
Updated: 2021/12/16

Alfa Aesar

Product number: J66114
Product name: [Glp1]-Apelin-13, human, bovine
Packaging: 1mg
Price: $94.3
Updated: 2021/12/16

Cayman Chemical

Product number: 15590
Product name: (Glp1)-Apelin-13
Purity: ≥95%
Packaging: 1mg
Price: $109
Updated: 2021/12/16

Tocris

Product number: 2420
Product name: [Pyr1]-Apelin-13
Packaging: 1
Price: $192
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FP109298
Product name: (Pyr 1)-Apelin-13
Packaging: 2mg
Price: $273
Updated: 2021/12/16

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PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH Chemical Properties,Usage,Production

Uses

The apelin gene encodes a pre-proprotein that is processed to generate bioactive peptides consisting of 36, 17, or 13 amino acids: apelin-36 , apelin-17, and apelin-13 , respectively. Apelin-13 is an endogenous ligand of the APJ receptor, activating this G protein-coupled receptor with an EC50 value of 0.37 nM. (Glp1)-Apelin-13 is a pyroglutamylated form of apelin-13, in that the N-terminal glutamine residue is cyclized to pyroglutamic acid. Like apelin-13, this compound is a potent APJ receptor agonist (EC50 = 0.30 nM). (Glp1)-Apelin-13 is the major apelin isoform in the plasma of healthy human subjects. It can have vasoconstrictor and antipyretic effects in vitro and in vivo.

Definition

ChEBI: P-Glu-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe is a thirteen-membered polypeptide consisting of p-Glu, Arg, Pro, Arg, Leu, Ser, His, Lys, Gly, Pro, Met, Pro and Phe residues joined in sequence. It has a role as an apoptosis inhibitor, a neuroprotective agent and a human metabolite. It is a tautomer of a [Pyr1]apelin-13(2+).

storage

Store at -20°C

PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH Suppliers

China 106 France 1 Germany 1 Japan 2 The Netherlands 1 United Kingdom 2 United States 15 USA 1 Global 129

MedChemexpress LLC

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View Lastest Price from PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH manufacturers

Career Henan Chemical Co

Product: PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH 217082-60-5
Price: US $3.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100kg
Release date: 2019-07-11

217082-60-5, PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OHRelated Search:

Chromium picolinate H-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH

(GLP1)-APELIN-13, HUMAN, BOVINE

GLP-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE

(Glp1)-Apelin-13

5-Oxo-L-prolyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl-L-phenylalanine

Pyr-apelin-13

GLP-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE: GRPRLSHKGPMPF

[PE]APELIN-13, HUMAN, BOVINE

PYR-RPRLSHKGPMPF-OH

PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE

PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH

[PYR1]-APELIN-13

(PYR1)-APELIN-13 (HUMAN, BOVINE)

(PYR1)-APELIN-13 (HUMAN, BOVINE, MOUSE, RAT)

[PGLU1]APELIN (24-36), HUMAN, BOVINE

PGLU-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE

[Pyr1]-Apelin-13,XRPRLSHKGPMPF,[pGlu1]-Apelin-13, >98%

[pGlu1]-Apelin-13

L-Phenylalanine, 5-oxo-L-prolyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl-

PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH USP/EP/BP

3-Dimethyluric acid

(Pyr?)-Apelin-13 (human, bovine, mouse, rat) acetate salt

[Pyr1]-Apelin-13 trifluoroacetate salt

{Glp}-RPRLSHKGPMPF

[Pyr1]-Apelin 13, endogenous apelin receptor (APJ) agonist

217082-60-5

C69H108N22O16S

peptide