ChemicalBook > CAS DataBase List > O-Desmethyl Gefitinib

O-Desmethyl Gefitinib

Product Name: O-Desmethyl Gefitinib
CAS No.: 847949-49-9
Chemical Name: O-Desmethyl Gefitinib
Synonyms: M523595;Gefitinib-7;Gefitinib impurity H;O-Demethyl-Gefitinib;O-Desmethyl Gefitinib;Gefitinib Impurity 13;Gefitinib impurities133;D8-O-Desmethyl Gefitinib;Gefitinib impurity 11 HCl;O-Desmethyl Gefitinib, 1 mg
CBNumber: CB11176640
Molecular Formula: C21H22ClFN4O3
Formula Weight: 432.88
MOL File: 847949-49-9.mol

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O-Desmethyl Gefitinib Property

Melting point:: 117-120?C
storage temp.: -20°C Freezer
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
color: Yellow
biological source: synthetic
Stability:: Hygroscopic

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Safety

Safety Statements: 24/25
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 22365
Product name: O-Desmethyl Gefitinib
Purity: ≥98%
Packaging: 500μg
Price: $29
Updated: 2024/03/01

Cayman Chemical

Product number: 22365
Product name: O-Desmethyl Gefitinib
Purity: ≥98%
Packaging: 1mg
Price: $49
Updated: 2024/03/01

Cayman Chemical

Product number: 22365
Product name: O-Desmethyl Gefitinib
Purity: ≥98%
Packaging: 5mg
Price: $160
Updated: 2024/03/01

TRC

Product number: G304015
Product name: GefitinibImpurity13
Packaging: 50mg
Price: $210
Updated: 2021/12/16

Usbiological

Product number: 008578
Product name: O-Desmethyl Gefitinib
Packaging: 1mg
Price: $403
Updated: 2021/12/16

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O-Desmethyl Gefitinib Chemical Properties,Usage,Production

Chemical Properties

Yellow Solid

Uses

O-Desmethyl Gefitinib-d8 is the isotope labelled analog of O-Desmethyl Gefitinib (D291680); a major metabolite of Gefitinib (G304000) which is an antineoplastic.

Definition

ChEBI: O-desmethyl Gefitinib is a member of quinazolines.

Biological Activity

O-Desmethyl gefitinib is generated by the removal of a methyl group from gefitinib during the bodyμs metabolic processing of this compound within the body.

O-Desmethyl Gefitinib Preparation Products And Raw materials

Raw materials

Preparation Products

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O-Desmethyl Gefitinib Suppliers

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847949-49-9, O-Desmethyl GefitinibRelated Search:

4-methoxy-3-(3-morpholinopropoxy)-2-nitrobenzonitrile 4-Defluoro-4-hydroxy Gefitinib 6,7-Dimethoxy-3,4-dihydroquinazoline-4-one Gefitinib iMpurity N-(3-chloro-4-fluorophenyl)-6 ,7-dimethoxyquinazolin-4-amine Gefitinib N-Oxide 3-Deschloro-4-Desfluoro-4-Chloro-3-Fluorogefitinib 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yl acetate 2-aMino-4-Methoxy-5-(3-Morpholinopropoxy)benzaMide N-(3-chloro-4-fluorophenyl)-7 -methoxy-6-(3-morpholinopropoxy)-N-(3-morpholinopropyl)quinazolin-4-amine 3-(3-morpholinylpropoxy)-4-methoxybenzonitrile 4-Methoxy-5-(3-Morpholinopropoxy)-2-nitrobenzaMide Gefitinib-d6 4,4'-(propane-1,3-diyl)bismorpholine 1-[2-amino-1-(4-hydroxyphenyl)ethyl]cyclohexanol 7-DeMethyl Ivabradine O-DesMethyl Venlafaxine Cyclic IMpurity Benzaldehyde, 2-amino-4-methoxy-5-[3-(4-morpholinyl)propoxy]-

M523595

4-[(3-Chloro-4-fluorophenyl)amino]-6-[3-(4-morpholinyl)propoxy]-7-quinazolinol

O-Desmethyl Gefitinib

Gefitinib O-Desmethyl Impurity

Gefitinib Impurity 13

O-DesmethylGefitinibmetabolite

Gefitinib impurity H

7-Quinazolinol, 4-[(3-chloro-4-fluorophenyl)aMino]-6-[3-(4-Morpholinyl)propoxy]-

4-((3-chloro-4-fluorophenyl)amino)-6-(3-morpholinopropoxy)quinazolin-7-ol

Gefitinib impurity 6/O-Desmethyl Gefitinib/4-((3-chloro-4-fluorophenyl)amino)-6-(3-morpholinopropoxy)quinazolin-7-ol

4-(3-chloro-4-fluoroanilino)-6-(3-morpholin-4-ylpropoxy)-1H-quinazolin-7-one

O-Demethyl-Gefitinib

Gefitinib-7

Gefitinib impurity 11 HCl

N-(3-chloro-4-fluorophenyl)-6-methoxy-7-(3-morpholinopropoxy)quinazolin-4-amine

Gefitinib impurities133

4-(3-chloro-4-fluoro-anilino)-6-(3-morpholinopropoxy)quinazolin-7-ol

human,Gefitinib,O-Desmethyl gefitinib,ODesmethyl gefitinib,plasma,inhibit,HER1,EGFR,CYP2D6,Epidermal growth factor receptor,O Desmethyl gefitinib,ErbB-1,Inhibitor

4-[(3-Chloro-4-fluorophenyl)amino]-6-[3-(morpholin-4-yl)propoxy]quinazolin-7-ol (O-Demethylgefitinib)

O-Desmethyl gefitinib, 10 mM in DMSO

<i>O</i>-Desmethyl gefitinib

Gefitinib Impurity (O-Desmethyl Gefitinib): 4-[(3-Chloro-4-fluorophenyl)amino]-6-[3-(4-morpholinyl)propoxy]-7-quinazolinol

D8-O-Desmethyl Gefitinib

O-Desmethyl Gefitinib, 1 mg

847949-49-9

C21H22ClFN4O3

Intermediates & Fine Chemicals

Metabolites & Impurities

Pharmaceuticals

Various Metabolites and Impurities