3-Deschloro-4-Desfluoro-4-Chloro-3-Fluorogefitinib

Product Name: 3-Deschloro-4-Desfluoro-4-Chloro-3-Fluorogefitinib
CAS No.: 1603814-04-5
Chemical Name: 3-Deschloro-4-Desfluoro-4-Chloro-3-Fluorogefitinib
Synonyms: Desfluoro Gefitinib;Gefitinib Impurity 16;Gefitinib Impurity HCl;Gefitinib EP impurity B;GefitinibEPImpurityBDiHCl;Gefitinib Related Compound B;Gefitinib related substance B;3-Deschloro-4-Desfluoro-4-Chloro-3-Fluorogefitinib;Gefitinib EP Impurity B DiHCl (Gefitinib USP Related Compound B DiHCl);N-(4-Chloro-3-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine
CBNumber: CB62741701
Molecular Formula: C22H24ClFN4O3
Formula Weight: 446.9
MOL File: 1603814-04-5.mol

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3-Deschloro-4-Desfluoro-4-Chloro-3-Fluorogefitinib Property

Melting point:: 180-183oC
Boiling point:: 585.0±50.0 °C(Predicted)
Density: 1.322±0.06 g/cm3(Predicted)
storage temp.: Refrigerator
solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated)
form: Solid
pka: 7.00±0.10(Predicted)
color: Off-White to Light Brown
Major Application: pharmaceutical

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Safety

WGK Germany: WGK 3
Storage Class: 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications: Acute Tox. 4 Oral
Aquatic Chronic 2
Carc. 2
Eye Dam. 1
Repr. 1B
Skin Irrit. 2
STOT RE 2 Oral

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H351Suspected of causing cancer

H373May cause damage to organs through prolonged or repeated exposure

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

TRC

Product number: D289540
Product name: 3-Deschloro-4-desfluoro-4-chloro-3-fluoroGefitinib
Packaging: 1g
Price: $1455
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 45080
Product name: 3-Deschloro-4-desfluoro-4-chloro-3-fluoroGefitinib
Packaging: 1g
Price: $2200
Updated: 2021/12/16

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3-Deschloro-4-Desfluoro-4-Chloro-3-Fluorogefitinib Chemical Properties,Usage,Production

Uses

3-Deschloro-4-desfluoro-4-chloro-3-fluoro Gefitinib is an impurity of Gefitinib (G304000); a tyrosine kinase inhibitor that targets the epidermal growth factor receptor (EGFR).

3-Deschloro-4-Desfluoro-4-Chloro-3-Fluorogefitinib Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Deschloro-4-Desfluoro-4-Chloro-3-Fluorogefitinib Suppliers

China 37 India 5 United States 3 Global 45

Daicel Chiral Technologies (China)CO.,LTD

Tel: 021-50460086-9 15921403865
Fax: +86-21-50462321
Email: han_yajun@dctc.daicel.com
Country: China
ProdList: 7440
Advantage: 65

BOC Sciences

Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 12952
Advantage: 65

Shanghai Kewel Chemical Co., Ltd.

Tel: 021-64609169 18901607656
Fax: 021-64609160
Email: greensnown@163.com
Country: China
ProdList: 9906
Advantage: 50

Nanjing XiZe Biotechnology CO., Ltd.

Tel: 025-66023220 15250997978
Fax: 025-58362220
Email: 1511893459@qq.com
Country: China
ProdList: 4876
Advantage: 55

Jinan Kaixi Biotechnology Co., Ltd.

Tel: 13370511208; 15853141736
Fax: -
Email: 461667177@qq.com
Country: China
ProdList: 702
Advantage: 55

Roark Standards

Tel: 0755-83552066 15986688328
Fax: 0755-83552066
Email: service@roarkstandards.com
Country: China
ProdList: 1442
Advantage: 58

Hubei Yangxin Medical Technology Co., Ltd.

Tel: 15374522761
Fax: QQ:2853117752
Email: 3003392093@yongstandards.com
Country: China
ProdList: 9997
Advantage: 55

Aikon International Limited

Tel: 025-58851090 15955137747
Fax: (6)02557626880
Email: sales01@aikonchem.com
Country: China
ProdList: 15949
Advantage: 58

Cool Pharm, Ltd

Tel: 021-58581007 18019463053
Fax: 021-50966098
Email: sales@coolpharm.com
Country: China
ProdList: 10000
Advantage: 58

Shaanxi Jiandu Pharmaceutical Chemical Co. Ltd.

Tel: 029-88380327 17691182729
Fax: 029-88380327
Email: 1018@dideu.com
Country: China
ProdList: 2011
Advantage: 58

1603814-04-5, 3-Deschloro-4-Desfluoro-4-Chloro-3-FluorogefitinibRelated Search:

4-Defluoro-4-hydroxy Gefitinib 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one Gefitinib-d6 N-(3-chloro-4-fluorophenyl)-6 ,7-dimethoxyquinazolin-4-amine 3,4-Dihydro-7-methoxy-4-oxoquinazolin-6-yl acetate Gefitinib iMpurity Gefitinib 3-DesMorpholinyl-3-hydroxyethylaMino Gefitinib 4-Methoxy-5-(3-Morpholinopropoxy)-2-nitrobenzaMide 3,4-Dichloroaniline N-(3-chloro-4-fluorophenyl)-7 -methoxy-6-(3-morpholinopropoxy)-N-(3-morpholinopropyl)quinazolin-4-amine 2-aMino-4-Methoxy-5-(3-Morpholinopropoxy)benzaMide 6,7-Dimethoxy-3,4-dihydroquinazoline-4-one 4-(3-Chloropropyl)morpholine 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yl acetate O-Desmethyl Gefitinib Gefitinib 3,4-difluoro iMpurity Gefitinib 3,4-Difluoro Impurity HCl

3-Deschloro-4-Desfluoro-4-Chloro-3-Fluorogefitinib

Desfluoro Gefitinib

Gefitinib EP impurity B

N-(4-Chloro-3-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine

Gefitinib Impurity 16

Gefitinib Impurity HCl (3-Deschloro-4-Desfluoro-4-Chloro-3-Fluoro Gefitinib HCl)

4-Quinazolinamine, N-(4-chloro-3-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-

Gefitinib Impurity HCl

N-(4-Chloro-3-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine

Gefitinib related substance B

GefitinibEPImpurityBDiHCl

N-(4-Chloro-3-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine

Gefitinib Related Compound B

Gefitinib EP Impurity B DiHCl (Gefitinib USP Related Compound B DiHCl)

1603814-04-5

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