ChemicalBook > CAS DataBase List > 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one

7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one

Product Name
7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one
CAS No.
199327-61-2
Chemical Name
7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one
Synonyms
Gefitinib-8;quinazolin-4(3H);Gefitinib iMpurity F;Gefitinib Impurity 14;Gefitinib Impurity 17;Gefintinib Impurity 5;Getitinib interMediate;Gefitinib impurities132;Gefitinib impurities135;InterMediate of Gefitinib
CBNumber
CB21477111
Molecular Formula
C16H21N3O4
Formula Weight
319.36
MOL File
199327-61-2.mol
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7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one Property

Melting point:
233-236 °C
Boiling point:
519.5±60.0 °C(Predicted)
Density 
1.32±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
7.10±0.10(Predicted)
color 
White to Off-White
CAS DataBase Reference
199327-61-2(CAS DataBase Reference)
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Safety

HS Code 
2933599590
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

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N-Bromosuccinimide Price

TRC
Product number
M264670
Product name
7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one
Packaging
100mg
Price
$95
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0167548
Product name
7-METHOXY-6-(3-MORPHOLIN-4-YL-PROPOXY)-3H-QUINAZOLIN-4-ONE
Purity
95.00%
Packaging
1G
Price
$918.23
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0167548
Product name
7-METHOXY-6-(3-MORPHOLIN-4-YL-PROPOXY)-3H-QUINAZOLIN-4-ONE
Purity
95.00%
Packaging
10G
Price
$4030.95
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0167548
Product name
7-METHOXY-6-(3-MORPHOLIN-4-YL-PROPOXY)-3H-QUINAZOLIN-4-ONE
Purity
95.00%
Packaging
100G
Price
$12647.25
Updated
2021/12/16
AK Scientific
Product number
X2633
Product name
7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one
Packaging
1g
Price
$94
Updated
2021/12/16
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7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one Chemical Properties,Usage,Production

Description

7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one is a pharmaceutical intermediate used in the preparation of gefitinib, an orally active selective inhibitor of the epidermal growth factor receptor tyrosine kinase, an enzyme that regulates intracellular signalling pathways that associated with the proliferation and survival of cancer cells.

Chemical Properties

White Solid

Uses

Gefitinib intermediate.

7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one Preparation Products And Raw materials

Raw materials

Preparation Products

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7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one Suppliers

Canada 2 China 232 India 25 United States 10 Global 269
Biocompounds Pharmaceutical Inc.
Tel
21-57687675
Fax
+86-21-57687169
Email
yanjie@biocompounds.com
Country
China
ProdList
55
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62
Shanghai xiao nai medical technology co., LTD
Tel
15800465632
Fax
QQ:37837302
Email
jiagaolong@126.com
Country
China
ProdList
47
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94838
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
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61
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9984
Advantage
60
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel
+86-21-54098501
Fax
+86-21-54096319
Email
sales@sinch.com.cn
Country
China
ProdList
11605
Advantage
64
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
zhangsn@titansci.com
Country
China
ProdList
14113
Advantage
59
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696;
Email
info@hanhongsci.com
Country
China
ProdList
42982
Advantage
64
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
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View Lastest Price from 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one manufacturers

Nanjing Fred Technology Co., Ltd
Product
7-methoxy-6-(3-morpholin-4-yl-propoxy）quinazolin-4(3H)-one 199327-61-2
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%(HPLC)
Supply Ability
2tons
Release date
2023-12-13
Hebei shuoxi biotechnology co. LTD
Product
7-methoxy-6-(3-morpholin-4-ylpropoxy)-1H-quinazolin-4-one 199327-61-2
Price
US $50.00/g
Min. Order
10g
Purity
99.8%
Supply Ability
10tons
Release date
2020-04-17
Career Henan Chemical Co
Product
7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one 199327-61-2
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
500kg
Release date
2018-08-16

199327-61-2, 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-oneRelated Search:

Methoxydiethylborane m-Anisyl alcohol p-Anisidine POLY(ETHYLENE GLYCOL) METHYL ETHER ACRYLATE 4-Methoxybenzoic acid p-Anisaldehyde Anisole Methoxyacetic acid (Trifluoromethoxy)benzene Gefitinib-d6 Gefitinib 6-Hydroxy-7-methoxy-3,4-dihydroquinazolin-4-one 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol 2-Amino-4-methoxy-5-(3-morpholinopropoxy)benzonitrile 3,4-Dihydro-7-methoxy-4-oxoquinazolin-6-yl acetate 4-(3-Chloropropyl)morpholine Gefitinib Impurity 11 6,7-Dimethoxy-3,4-dihydroquinazoline-4-one

  • 7-Methoxy-6-(3-Morpholin-4-ylpropoxy) Quinazolin- 4-(3H)-One Gefitinib HCL InterMediates G5
  • Getitinib interMediate
  • Gefitinib iMpurity F
  • 7-METHOXY-6-(3-MORPHOLINOPROPOXY)QUINAZOLIN-4(3H)-ONE
  • 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one
  • 7-Methoxy-6-(3-morpholinopropoxy)-3,4-dihydroquinazolin-4-one
  • 7-Methoxy-6-[3-(4-morpholinyl)propoxy]-4(3H)-quinazolinone
  • Gefitinib Impurity 14
  • 7-methoxy-6-(3-morpholin-4-ylpropoxy)-1H-quinazolin-4-one
  • 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quainazolin-4(3H)-one
  • 6-(3-morpholinopropoxy)-7-methoxyquinazolin-4(3H)-one
  • 7-Methoxy-6-(3-morpholinopropoxy)
  • quinazolin-4(3H)
  • 7-Methoxy-6-(3-morpholin-4-yl-propoxy)-3H-quinazolin-4-one
  • 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin
  • 7-Methoxy-6-[3-(Morpholin-4-yl)propoxy]-3,4-dihydroquinazolin-4-one
  • Gefitinib Impurity 17
  • InterMediate of Gefitinib
  • 7-Methoxy-6-(3-Morpholin-4-yl-propoxy) -4-(3H)-quinazolinone
  • Gefintinib Impurity 5
  • Gefitinib-8
  • 4(3H)-Quinazolinone, 7-methoxy-6-[3-(4-morpholinyl)propoxy]-
  • 7-METHOXY-6-(MORPHOLIN-4-YL PROPY L)QUINAZOLIN-4-(3H)-ONE
  • Gefitinib impurities132
  • Gefitinib impurities135
  • TIANFU-CHEM - 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one
  • 7-Methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4(1H)-one
  • 7-methoxy-6- (3-morpholine-4-ylpropyloxy) quinazoline-4 (3H) - one
  • 7-Methoxy-6-(3-morpholinopropoxy)quizolin-4(3H)-one
  • 7-methoxy-6-(4-morpholinobutyl) quinazolin-4(3H)-one
  • 199327-61-2
  • 31936
  • Gefitinib INTERMEDIATES
  • Heterocycles
  • Intermediates
  • Intermediates & Fine Chemicals
  • Pharmaceuticals