O-Desmorpholinopropyl Gefitinib

Product Name: O-Desmorpholinopropyl Gefitinib
CAS No.: 184475-71-6
Chemical Name: O-Desmorpholinopropyl Gefitinib
Synonyms: 4-(3-chloro-4-fluoroanilino)-7-methoxyquinazolin-6-ol;FAAH-IN-2;Des-Gefitinib;N-(3-Chloro-4-f;FAAH inhibitor 2;Gefitinib iMpurity C;Gefitinib Intermediate 1;Gefitinib interMediate VII;FAAH-IN-2 (Gefitinib Impurity);O-Desmorpholinopropyl Gefitinib
CBNumber: CB31176644
Molecular Formula: C15H11ClFN3O2
Formula Weight: 319.72
MOL File: 184475-71-6.mol

More

Less

O-Desmorpholinopropyl Gefitinib Property

Melting point:: >260°C (dec.)
Boiling point:: 478.8±45.0 °C(Predicted)
Density: 1.489±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility: DMSO (Slightly), Methanol (Very Slightly, Heated)
form: Solid
pka: 8.18±0.40(Predicted)
color: Pale Beige to Beige

More

Less

Safety

HS Code: 2933.59.8000

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

TCI Chemical

Product number: C3647
Product name: 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol
Packaging: 1G
Price: $64
Updated: 2024/03/01

TCI Chemical

Product number: C3647
Product name: 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol
Packaging: 5G
Price: $218
Updated: 2024/03/01

TRC

Product number: D296830
Product name: O-DesmorpholinopropylGefitinib
Packaging: 5g
Price: $225
Updated: 2021/12/16

Usbiological

Product number: 008737
Product name: O-Desmorpholinopropyl Gefitinib
Packaging: 100mg
Price: $418
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD21367
Product name: O-Desmorpholinopropyl gefitinib
Packaging: 5G
Price: $550
Updated: 2021/12/16

More

Less

O-Desmorpholinopropyl Gefitinib Chemical Properties,Usage,Production

Description

O-Desmorpholinopropyl Gefitinib is a metabolite of Gefitinib, a potent inhibitor of tyrosine phosporylation in EGFR. The chemical structure of O-Desmorpholinopropyl Gefitinib consists of a quinazoline-6-ol core with a phenylamino group attached to a chloro-fluoro-phenyl ring, enabling it to interact with multiple biological targets. It is involved in inhibiting enzymes such as cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS).

Chemical Properties

Tan Solid

Uses

A metabolite of Gefitinib.

Definition

ChEBI: O-Desmorpholinopropyl Gefitinib is a member of quinazolines.

O-Desmorpholinopropyl Gefitinib Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

O-Desmorpholinopropyl Gefitinib Suppliers

Americas 1 Canada 1 China 176 China Hong Kong 1 Europe 1 Germany 1 India 11 Japan 1 United Kingdom 1 United States 15 Global 209

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2923
Advantage: 55

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9984
Advantage: 60

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: zhangsn@titansci.com
Country: China
ProdList: 14113
Advantage: 59

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 17938
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696;
Email: info@hanhongsci.com
Country: China
ProdList: 42982
Advantage: 64

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32344
Advantage: 50

XiaoGan ShenYuan ChemPharm co,ltd

Tel: 0712-0712-2580635 15527768850
Email: 1791901229@qq.com
Country: China
ProdList: 8849
Advantage: 52

Jinan Trio PharmaTech Co., Ltd.

Tel: +86 (531) 88811783
Fax: +86 (531) 55696010 QQ 1762738062
Email: sales@trio-pharmatech.com (International market)
Country: China
ProdList: 1856
Advantage: 62

China Langchem Inc.

Tel: 0086-21-58956006
Fax: 0086-21-58956100
Country: China
ProdList: 7815
Advantage: 57

More

Less

View Lastest Price from O-Desmorpholinopropyl Gefitinib manufacturers

Henan Fengda Chemical Co., Ltd

Product: 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol 184475-71-6
Price: US $5.00-0.10/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-03-27

Nanjing Fred Technology Co., Ltd

Product: 4-(3-chloro-4-fluorophenylami-no)-7-methoxyquinazolin-6-ol 184475-71-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%(HPLC)
Supply Ability: 5000kg
Release date: 2023-12-13

Career Henan Chemical Co

Product: 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol 184475-71-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2018-07-26

184475-71-6, O-Desmorpholinopropyl GefitinibRelated Search:

Gefitinib Impurity 11 Gefitinib-d6 6-Hydroxy-7-methoxy-3,4-dihydroquinazolin-4-one 2-Amino-4-methoxy-5-(3-morpholinopropoxy)benzonitrile 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one 3,4-Dihydro-7-methoxy-4-oxoquinazolin-6-yl acetate 4-(3-Chloropropyl)morpholine 3-Chloro-4-fluoroaniline 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yl acetate (Trifluoromethoxy)benzene Sulfaquinoxaline 4-Methoxyphenol Anisole Quinoxaline Gefitinib Chloro Impurity Gefitinib Impurity 8 6,7-Dimethoxy-3,4-dihydroquinazoline-4-one Gefitinib 3,4-Difluoro Impurity HCl

FAAH-IN-2

4-(3-Chloro-4-fluorophenylamino)-6-hydroxy-7-methoxyquinazoline

4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinol

O-Desmorpholinopropyl Gefitinib

4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol

Gefitinib interMediate VII

4-(3-Chlor-4-fluorophenylamino)-7-methoxyquinazolin-6-ol

Gefitinib Intermediate 1

4-(3-Chloro-4-fluoroanilino)-6-hydroxy-7-methoxyquinazoline

N-(3-Chloro-4-f

FAAH-IN-2 (O-Desmorpholinopropyl Gefitinib)

6-Quinazolinol,4-[(3-chloro-4-fluorophenyl)aMino]-7-Methoxy-

Gefitinib iMpurity C

Gefitinib Impurity 12 (O-Desmorpholinopropyl Gefitinib)

FAAH inhibitor 2

Gefitinib O-Desmorpholinopropyl Impurity

4-(3-chloro-4-fluoroanilino)-7-methoxyquinazolin-6-ol

Des-Gefitinib

4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-ol (O-Desmorpholinopropylgefitinib)

FAAH-IN-2 (Gefitinib Impurity)

4- (3-Chloro-4-fluorophenylamino) -7-methoxyquinoline-6-alcohol

184475-71-6

C15H11ClFN3O2

Gefitinib

Various Metabolites and Impurities

Intermediates & Fine Chemicals

Metabolites & Impurities

Pharmaceuticals