O-Desmorpholinopropyl Gefitinib

Product Name: O-Desmorpholinopropyl Gefitinib
CAS No.: 184475-71-6
Chemical Name: O-Desmorpholinopropyl Gefitinib
Synonyms: 4-(3-chloro-4-fluoroanilino)-7-methoxyquinazolin-6-ol;FAAH-IN-2;Des-Gefitinib;N-(3-Chloro-4-f;FAAH inhibitor 2;Gefitinib iMpurity C;Gefitinib Intermediate 1;Gefitinib interMediate VII;FAAH-IN-2 (Gefitinib Impurity);O-Desmorpholinopropyl Gefitinib
CBNumber: CB31176644
Molecular Formula: C15H11ClFN3O2
Formula Weight: 319.72
MOL File: 184475-71-6.mol

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O-Desmorpholinopropyl Gefitinib Property

Melting point:: >260°C (dec.)
Boiling point:: 478.8±45.0 °C(Predicted)
Density: 1.489±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility: DMSO (Slightly), Methanol (Very Slightly, Heated)
form: Solid
pka: 8.18±0.40(Predicted)
color: Pale Beige to Beige

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Safety

HS Code: 2933.59.8000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical

Product number: C3647
Product name: 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol
Packaging: 1G
Price: $64
Updated: 2024/03/01

TCI Chemical

Product number: C3647
Product name: 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol
Packaging: 5G
Price: $218
Updated: 2024/03/01

TRC

Product number: D296830
Product name: O-DesmorpholinopropylGefitinib
Packaging: 5g
Price: $225
Updated: 2021/12/16

Usbiological

Product number: 008737
Product name: O-Desmorpholinopropyl Gefitinib
Packaging: 100mg
Price: $418
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD21367
Product name: O-Desmorpholinopropyl gefitinib
Packaging: 5G
Price: $550
Updated: 2021/12/16

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O-Desmorpholinopropyl Gefitinib Chemical Properties,Usage,Production

Description

O-Desmorpholinopropyl Gefitinib is a metabolite of Gefitinib, a potent inhibitor of tyrosine phosporylation in EGFR. The chemical structure of O-Desmorpholinopropyl Gefitinib consists of a quinazoline-6-ol core with a phenylamino group attached to a chloro-fluoro-phenyl ring, enabling it to interact with multiple biological targets. It is involved in inhibiting enzymes such as cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS).

Chemical Properties

Tan Solid

Uses

A metabolite of Gefitinib.

Definition

ChEBI: O-Desmorpholinopropyl Gefitinib is a member of quinazolines.

O-Desmorpholinopropyl Gefitinib Preparation Products And Raw materials

Raw materials

Preparation Products

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O-Desmorpholinopropyl Gefitinib Suppliers

Americas 1 Canada 1 China 185 China Hong Kong 1 Europe 1 Germany 1 India 11 Japan 1 United Kingdom 1 United States 15 Global 218

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2922
Advantage: 55

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
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JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14103
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Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 19172
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42958
Advantage: 64

Chemsky（shanghai）International Co.,Ltd.

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Email: shchemsky@sina.com
Country: China
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XiaoGan ShenYuan ChemPharm co,ltd

Tel: 15527768850
Email: 1791901229@qq.com
Country: China
ProdList: 8843
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Jinan Trio PharmaTech Co., Ltd.

Tel: +86 (531) 88811783
Fax: +86 (531) 55696010 QQ 1762738062
Email: sales@trio-pharmatech.com (International market)
Country: China
ProdList: 1856
Advantage: 62

China Langchem Inc.

Tel: 0086-21-58956006
Fax: 0086-21-58956100
Country: China
ProdList: 7811
Advantage: 57

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View Lastest Price from O-Desmorpholinopropyl Gefitinib manufacturers

Nanjing Fred Technology Co., Ltd

Product: 4-(3-chloro-4-fluorophenylami-no)-7-methoxyquinazolin-6-ol 184475-71-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%(HPLC)
Supply Ability: 5000kg
Release date: 2023-12-13

Henan Fengda Chemical Co., Ltd

Product: 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol 184475-71-6
Price: US $5.00-0.10/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-03-27

Career Henan Chemical Co

Product: 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol 184475-71-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2018-07-26

184475-71-6, O-Desmorpholinopropyl GefitinibRelated Search:

Gefitinib Impurity 11 Gefitinib-d6 6-Hydroxy-7-methoxy-3,4-dihydroquinazolin-4-one 2-Amino-4-methoxy-5-(3-morpholinopropoxy)benzonitrile 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one 3,4-Dihydro-7-methoxy-4-oxoquinazolin-6-yl acetate 4-(3-Chloropropyl)morpholine 3-Chloro-4-fluoroaniline 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yl acetate (Trifluoromethoxy)benzene Sulfaquinoxaline 4-Methoxyphenol Anisole Quinoxaline Gefitinib Chloro Impurity Gefitinib Impurity 8 6,7-Dimethoxy-3,4-dihydroquinazoline-4-one Gefitinib 3,4-Difluoro Impurity HCl

FAAH-IN-2

4-(3-Chloro-4-fluorophenylamino)-6-hydroxy-7-methoxyquinazoline

4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinol

O-Desmorpholinopropyl Gefitinib

4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol

Gefitinib interMediate VII

4-(3-Chlor-4-fluorophenylamino)-7-methoxyquinazolin-6-ol

Gefitinib Intermediate 1

4-(3-Chloro-4-fluoroanilino)-6-hydroxy-7-methoxyquinazoline

N-(3-Chloro-4-f

FAAH-IN-2 (O-Desmorpholinopropyl Gefitinib)

6-Quinazolinol,4-[(3-chloro-4-fluorophenyl)aMino]-7-Methoxy-

Gefitinib iMpurity C

Gefitinib Impurity 12 (O-Desmorpholinopropyl Gefitinib)

FAAH inhibitor 2

Gefitinib O-Desmorpholinopropyl Impurity

4-(3-chloro-4-fluoroanilino)-7-methoxyquinazolin-6-ol

Des-Gefitinib

4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-ol (O-Desmorpholinopropylgefitinib)

FAAH-IN-2 (Gefitinib Impurity)

4- (3-Chloro-4-fluorophenylamino) -7-methoxyquinoline-6-alcohol

184475-71-6

C15H11ClFN3O2

Gefitinib

Various Metabolites and Impurities

Intermediates & Fine Chemicals

Metabolites & Impurities

Pharmaceuticals