4-(3-Chloropropyl)morpholine
- Product Name
- 4-(3-Chloropropyl)morpholine
- CAS No.
- 7357-67-7
- Chemical Name
- 4-(3-Chloropropyl)morpholine
- Synonyms
- 4-(3-ChL;NSC 38889;NSC 28831;)-morphoL;N-(3-Chloropropyl)M;IFLAB-BB F2108-0002;Gefitinib iMpurity A;Gefitinib IMpurity VI;Gefitinib Impurity 81;3-morpholinopropylchloride
- CBNumber
- CB0240217
- Molecular Formula
- C7H14ClNO
- Formula Weight
- 163.65
- MOL File
- 7357-67-7.mol
4-(3-Chloropropyl)morpholine Property
- Melting point:
- NA
- Boiling point:
- 115°C/25mmHg(lit.)
- Density
- 1.0409 g/cm3
- RTECS
- QE0488000
- refractive index
- 1.4720-1.4760
- Flash point:
- 91 °C
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Oil
- pka
- 7.03±0.10(Predicted)
- Specific Gravity
- 1.08
- color
- Colourless to Yellow
- InChI
- InChI=1S/C7H14ClNO/c8-2-1-3-9-4-6-10-7-5-9/h1-7H2
- InChIKey
- PQECODMSWJOUAT-UHFFFAOYSA-N
- SMILES
- N1(CCCCl)CCOCC1
- CAS DataBase Reference
- 7357-67-7(CAS DataBase Reference)
Safety
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36/37/39
- HazardClass
- IRRITANT
- HS Code
- 2934999090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- C2602
- Product name
- 4-(3-Chloropropyl)morpholine
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $29
- Updated
- 2024/03/01
- Product number
- C2602
- Product name
- 4-(3-Chloropropyl)morpholine
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $92
- Updated
- 2024/03/01
- Product number
- H35222
- Product name
- 4-(3-Chloropropyl)morpholine, 95%
- Packaging
- 10g
- Price
- $57.65
- Updated
- 2024/03/01
- Product number
- H35222
- Product name
- 4-(3-Chloropropyl)morpholine, 95%
- Packaging
- 50g
- Price
- $185.65
- Updated
- 2024/03/01
- Product number
- C379750
- Product name
- 4-(3-Chloropropyl)morpholine
- Packaging
- 1g
- Price
- $80
- Updated
- 2021/12/16
4-(3-Chloropropyl)morpholine Chemical Properties,Usage,Production
Description
4-(3-Chloropropyl)morpholine is a hydrochloride salt of the potent inhibitor 4-(3-chloropropyl)morpholine. It has an inhibitory effect on cancer, and is used in chromatographic science to separate amines from aliphatic hydrocarbons. 4-(3-Chloropropyl)morpholine inhibits epidermal growth factor (EGF) and has been shown to have a potent inhibitory effect on EGF receptor tyrosine kinase activity. It also inhibits the proliferation of cells by inhibiting DNA synthesis. This compound causes cell death through the inhibition of protein synthesis, which may be due to its ability to inhibit nucleophilic reactions that are involved in protein synthesis. 4-(3-Chloropropyl)morpholine can also fluoresce under UV light, which makes it useful for research purposes.
Chemical Properties
Pale Yellow Oil
Uses
Gefitinib intermediate.
Application
4-(3-Chloropropyl)morpholine is an organic synthetic reagent or pharmaceutical intermediate used in the synthesis of gefitinib. It has cancer-inhibiting properties and inhibits epidermal growth factor (EGF). It also inhibits cell proliferation by inhibiting DNA synthesis.
4-(3-Chloropropyl)morpholine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-(3-Chloropropyl)morpholine manufacturers
- Product
- 4-(3-Chloropropyl)morpholine 7357-67-7
- Price
- US $8.00-0.60/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-01-14
- Product
- 4-(3-Chloropropyl)morpholine 7357-67-7
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- ton
- Release date
- 2023-11-14
- Product
- N-(3-Chloropropyl)morpholine 7357-67-7
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98.0%min
- Supply Ability
- 100kg
- Release date
- 2023-03-11