ChemicalBook > CAS DataBase List > 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one
7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one
- Product Name
- 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one
- CAS No.
- 199327-61-2
- Chemical Name
- 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one
- Synonyms
- Gefitinib-8;quinazolin-4(3H);Gefitinib iMpurity F;Gefitinib Impurity 14;Gefitinib Impurity 17;Gefintinib Impurity 5;Getitinib interMediate;Gefitinib impurities132;Gefitinib impurities135;InterMediate of Gefitinib
- CBNumber
- CB21477111
- Molecular Formula
- C16H21N3O4
- Formula Weight
- 319.36
- MOL File
- 199327-61-2.mol
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7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one Property
- Melting point:
- 233-236 °C
- Boiling point:
- 519.5±60.0 °C(Predicted)
- Density
- 1.32±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 7.10±0.10(Predicted)
- color
- White to Off-White
- CAS DataBase Reference
- 199327-61-2(CAS DataBase Reference)
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Safety
- HS Code
- 2933599590
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
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N-Bromosuccinimide Price
TRC
- Product number
- M264670
- Product name
- 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one
- Packaging
- 100mg
- Price
- $95
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- CHM0167548
- Product name
- 7-METHOXY-6-(3-MORPHOLIN-4-YL-PROPOXY)-3H-QUINAZOLIN-4-ONE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $918.23
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- CHM0167548
- Product name
- 7-METHOXY-6-(3-MORPHOLIN-4-YL-PROPOXY)-3H-QUINAZOLIN-4-ONE
- Purity
- 95.00%
- Packaging
- 10G
- Price
- $4030.95
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- CHM0167548
- Product name
- 7-METHOXY-6-(3-MORPHOLIN-4-YL-PROPOXY)-3H-QUINAZOLIN-4-ONE
- Purity
- 95.00%
- Packaging
- 100G
- Price
- $12647.25
- Updated
- 2021/12/16
AK Scientific
- Product number
- X2633
- Product name
- 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one
- Packaging
- 1g
- Price
- $94
- Updated
- 2021/12/16
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7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one Chemical Properties,Usage,Production
Description
7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one is a pharmaceutical intermediate used in the preparation of gefitinib, an orally active selective inhibitor of the epidermal growth factor receptor tyrosine kinase, an enzyme that regulates intracellular signalling pathways that associated with the proliferation and survival of cancer cells.
Chemical Properties
White Solid
Uses
Gefitinib intermediate.
7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one Preparation Products And Raw materials
Raw materials
Preparation Products
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7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one Suppliers
- Tel
- --
- Fax
- --
- info@trc-canada.com
- Country
- Canada
- ProdList
- 6038
- Advantage
- 71
- Tel
- --
- Fax
- --
- chemist@dalton.com
- Country
- Canada
- ProdList
- 965
- Advantage
- 78
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View Lastest Price from 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one manufacturers
Nanjing Fred Technology Co., Ltd
- Product
- 7-methoxy-6-(3-morpholin-4-yl-propoxy)quinazolin-4(3H)-one 199327-61-2
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 99%(HPLC)
- Supply Ability
- 2tons
- Release date
- 2023-12-13
Zibo Hangyu Biotechnology Development Co., Ltd
- Product
- 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one 199327-61-2
- Price
- US $110.00-560.00/g
- Min. Order
- 5g
- Purity
- 99%
- Supply Ability
- 50
- Release date
- 2024-07-12
Hebei shuoxi biotechnology co. LTD
- Product
- 7-methoxy-6-(3-morpholin-4-ylpropoxy)-1H-quinazolin-4-one 199327-61-2
- Price
- US $50.00/g
- Min. Order
- 10g
- Purity
- 99.8%
- Supply Ability
- 10tons
- Release date
- 2020-04-17
199327-61-2, 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-oneRelated Search:
Methoxydiethylborane
m-Anisyl alcohol
p-Anisidine
POLY(ETHYLENE GLYCOL) METHYL ETHER ACRYLATE
4-Methoxybenzoic acid
p-Anisaldehyde
Anisole
Methoxyacetic acid
(Trifluoromethoxy)benzene
Gefitinib-d6
Gefitinib
6-Hydroxy-7-methoxy-3,4-dihydroquinazolin-4-one
4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol
2-Amino-4-methoxy-5-(3-morpholinopropoxy)benzonitrile
3,4-Dihydro-7-methoxy-4-oxoquinazolin-6-yl acetate
4-(3-Chloropropyl)morpholine
Gefitinib Impurity 11
6,7-Dimethoxy-3,4-dihydroquinazoline-4-one