Clanfenur
- Product Name
- Clanfenur
- CAS No.
- 51213-99-1
- Chemical Name
- Clanfenur
- Synonyms
- Clanfenur;Clanfenur, 10 mM in DMSO;3-(4-chlorophenyl)-1-[2-(dimethylamino)-6-fluorobenzoyl]urea;N-((4-Chlorophenyl)carbamoyl)-2-(dimethylamino)-6-fluorobenzamide;N-[[(4-chlorophenyl)amino]carbonyl]-2-(dimethylamino)-6-fluorobenzamide;Benzamide,N-[[(4-chlorophenyl)amino]carbonyl]-2-(dimethylamino)-6-fluoro-
- CBNumber
- CB11178316
- Molecular Formula
- C16H15ClFN3O2
- Formula Weight
- 335.76
- MOL File
- 51213-99-1.mol
Clanfenur Property
- Density
- 1.371±0.06 g/cm3(Predicted)
- solubility
- Acetonitrile: Slightly soluble: 0.1-1 mg/mL
DMSO: Sparingly soluble: 1-10 mg/mL - form
- Solid
- pka
- 9.37±0.46(Predicted)
- color
- White to off-white
N-Bromosuccinimide Price
- Product number
- API0011066
- Product name
- CLANFENUR
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $499.51
- Updated
- 2021/12/16
- Product number
- DC9868
- Product name
- Clanfenur
- Purity
- >98%
- Packaging
- 25mg
- Price
- $800
- Updated
- 2021/12/16
- Product number
- DC9868
- Product name
- Clanfenur
- Purity
- >98%
- Packaging
- 50mg
- Price
- $1600
- Updated
- 2021/12/16
- Product number
- DC9868
- Product name
- Clanfenur
- Purity
- >98%
- Packaging
- 10mg
- Price
- $450
- Updated
- 2021/12/16
Clanfenur Chemical Properties,Usage,Production
Uses
Clanfenur is a substituted benzoylphenylurea, an analogue of the pesticide fenfluramide, with potential antineoplastic activity. Clanfenur can bind to the colchicine-binding site on β-tubulin, inhibit microtubule polymerization, and thus prevent tumor cell replication[1].
References
[1] J D Jonkman-de Vries, et al. Pharmaceutical development of a parenteral formulation of the investigational anticancer drug clanfenur. PDA J Pharm Sci Technol. 1997 Mar-Apr;51(2):89-95. PMID:9146040
[2] H P HOFS J G M. Effects of benzoylphenyl ureas on growth of B16 melanoma cells in vitro and in vivo.[J]. Investigational New Drugs, 1991, 9 3: 227-232. DOI: 10.1007/bf00176975
[3] V K JENKINS. Effects of diflubenzuron and clanfenur on mouse bone marrow cells.[J]. Investigational New Drugs, 1993, 11 4: 279-289. DOI: 10.1007/bf00874426
Clanfenur Preparation Products And Raw materials
Raw materials
Preparation Products
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