3-BROMO-1H-PYRAZOLE

Product Name: 3-BROMO-1H-PYRAZOLE
CAS No.: 14521-80-3
Chemical Name: 3-BROMO-1H-PYRAZOLE
Synonyms: 3-Bromopyrazole 97%;MFCD13189492;3-BROMO-PYRAZOLE;3-BROMO-1H-PYRAZOLE;3-bromo-2H-pyrazole;1H-PYRAZOLE, 3-BROMO-;1H-Pyrazole,3-bromo-(9CI);3-Bromo-1H-Pyrazole(WX900043);3-Bromopyrazole/3-broMo-1H-pyrazole
CBNumber: CB1121665
Molecular Formula: C3H3BrN2
Formula Weight: 146.97
MOL File: 14521-80-3.mol

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3-BROMO-1H-PYRAZOLE Property

Melting point:: 60-65°C
Boiling point:: 70-72 °C(Press: 0.1 Torr)
Density: 1.904±0.06 g/cm3(Predicted)
storage temp.: -20°C
form: crystals
pka: 10.88±0.10(Predicted)
color: White-pale yellow
InChI: InChI=1S/C3H3BrN2/c4-3-1-2-5-6-3/h1-2H,(H,5,6)
InChIKey: XHZWFUVEKDDQPF-UHFFFAOYSA-N
SMILES: N1C=CC(Br)=N1
CAS DataBase Reference: 14521-80-3

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Safety

Hazard Codes: Xn
Risk Statements: 22-36/37/38
Safety Statements: 26-37/39
WGK Germany: 1
HS Code: 2933119000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 723924
Product name: 3-Bromopyrazole
Purity: 97%
Packaging: 1g
Price: $170
Updated: 2025/07/31

Sigma-Aldrich

Product number: 723924
Product name: 3-Bromopyrazole
Purity: 97%
Packaging: 500mg
Price: $123
Updated: 2023/06/20

TRC

Product number: B687345
Product name: 3-Bromopyrazole
Packaging: 1g
Price: $45
Updated: 2021/12/16

Matrix Scientific

Product number: 067227
Product name: 3-Bromopyrazole
Purity: 97%
Packaging: 1g
Price: $49
Updated: 2021/12/16

Frontier Specialty Chemicals

Product number: CAPOB13736
Product name: 3-Bromo-1H-pyrazole
Purity: 95%
Packaging: 1g
Price: $50
Updated: 2021/12/16

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3-BROMO-1H-PYRAZOLE Chemical Properties,Usage,Production

Uses

3-Bromopyrazole is a useful synthetic intermediate in the synthesis of Rynaxypyr (C325380); an insecticidal anthranilic diamide that acts as a potent and selective ryanodine receptor activator.

Synthesis

500011-84-7

14521-80-3

General procedure for the synthesis of 3-bromopyrazole from 1-(dimethylaminosulfonyl)-3-bromopyrazole: 3-bromo-N,N-dimethyl-1H-pyrazole-1-sulfonamide (5.83 g) obtained in step B was mixed with trifluoroacetic acid (9.0 mL) and the reaction was stirred for 2 hours at room temperature. Upon completion of the reaction, ethyl acetate was added to the mixture, followed by neutralization of the reaction solution with saturated aqueous sodium bicarbonate and washing with saturated aqueous sodium chloride. The organic layer was separated, dried with anhydrous sodium sulfate and concentrated under reduced pressure to remove the solvent. The resulting crude product was purified by silica gel column chromatography (eluent: ethyl acetate/hexane) to give the final target compound 3-bromopyrazole (2.92 g). The product was characterized by 1H NMR (400 MHz, CDCl3): δ 6.37 (1H, d, J=2.4 Hz), 7.57 (1H, d, J=2.4 Hz).

References

[1] Patent: WO2006/68669, 2006, A1. Location in patent: Page/Page column 19; 24
[2] Patent: WO2003/106427, 2003, A2. Location in patent: Page 18
[3] Patent: WO2004/11447, 2004, A2. Location in patent: Page 42-43
[4] Patent: EP2818473, 2014, A1. Location in patent: Paragraph 0583
[5] Patent: US9113630, 2015, B2. Location in patent: Page/Page column 41; 42

3-BROMO-1H-PYRAZOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-BROMO-1H-PYRAZOLE Suppliers

China 234 Europe 1 Germany 1 India 7 Switzerland 1 The Netherlands 1 United Kingdom 2 United States 26 Global 273

Specs

Tel: --
Fax: --
Email: info@specs.net
Country: The Netherlands
ProdList: 6833
Advantage: 70

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View Lastest Price from 3-BROMO-1H-PYRAZOLE manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 3-BROMO-1H-PYRAZOLE 14521-80-3
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-18

Shaanxi Dideu Medichem Co. Ltd

Product: 3-Bromo-1H-pyrazole 14521-80-3
Price: US $130.00-850.00/g
Min. Order: 1g
Purity: 99.2%
Supply Ability: 20tons
Release date: 2019-12-31

Hebei Zhanyao Biotechnology Co. Ltd

Product: 3-BROMO-1H-PYRAZOLE 14521-80-3
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 tons
Release date: 2021-10-19

14521-80-3, 3-BROMO-1H-PYRAZOLERelated Search:

3-Methyl-4-bromo-1H-pyrazole 3-bromoH-pyrazolo[1,5-a]pyridine-5-carboxylic acid 4-(4-Bromopyrazol-1-yl)piperidine-1-carboxylic acid tert-butyl ester ETHYL3-BROMO-1H-PYRAZOLE4-CARBOXYLATE 4-Bromo-3,5-dimethylpyrazole 3-AMINO-4-BROMO-2-METHYLPYRAZOLE 4-bromopyrazolo[3,4-d]pyrimidine 4-BROMO-1H-PYRAZOLE-3-CARBOXAMIDE 4-bromo-1H-pyrazole-5-carboxylic acid,4-BROMO-2H-PYRAZOLE-3-CARBOXYLIC ACID 4-bromo-1H-pyrazolo[3,4-b]pyridine 4-Bromopyrazole-1-carboxylic acid tert-butyl ester 3-(5-BROMO-2-HYDROXYPHENYL)PYRAZOLE 4-BROMO-1H-PYRAZOLE-3-CARBONITRILE 4-BROMO-1H-PYRAZOLE 3-BROMO-1H-PYRAZOLE-4-CARBOXYLICACID 3-bromoH-pyrazolo[1,5-a]pyridine-2-carboxylic acid 7-BROMO-PYRAZOLO[1,5-A]PYRIDINE 3-AMINO-4-BROMO-1-METHYLPYRAZOLE

3-BROMO-PYRAZOLE

3-BROMO-1H-PYRAZOLE

1H-PYRAZOLE, 3-BROMO-

1H-Pyrazole,3-bromo-(9CI)

3-Bromopyrazole 97%

3-bromo-2H-pyrazole

MFCD13189492

3-Bromo-1H-Pyrazole(WX900043)

3-Bromopyrazole/3-broMo-1H-pyrazole

14521-80-3

14521-80-4

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