ChemicalBook > CAS DataBase List > trans-Methyl4-hydroxycyclohexanecarboxylate
trans-Methyl4-hydroxycyclohexanecarboxylate
- Product Name
- trans-Methyl4-hydroxycyclohexanecarboxylate
- CAS No.
- 6125-57-1
- Chemical Name
- trans-Methyl4-hydroxycyclohexanecarboxylate
- Synonyms
- Methyl trans-4-hydroxycyclohexane formate;trans-Methyl4-hydroxycyclohexanecarboxylate;Methyl rans-4-Hydroxycyclohexanecarboxylate;Methyl trans-4-Hydroxycyclohexanecarboxylate;Methyltrans-4-Hydroxycyclohexanecarboxylate>Methyl trans-4-hydroxycyclohexane-1-carboxylate;Methyl (1s,4s)-4-hydroxycyclohexane-1-carboxylate;Methyl trans-4-Hydroxycyclohexanecarboxylate;trans-4-Hydroxycyclohexanecarboxylic Acid Methyl Ester;Trans-Methyl 4-Hydroxycyclohexanecarboxylate(WXC01475)
- CBNumber
- CB11235206
- Molecular Formula
- C8H14O3
- Formula Weight
- 158.2
- MOL File
- 6125-57-1.mol
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trans-Methyl4-hydroxycyclohexanecarboxylate Property
- Boiling point:
- 125°C/0.3mmHg(lit.)
- Density
- 1.103
- refractive index
- 1.4693 (589.3 nm 23℃)
- storage temp.
- Sealed in dry,Room Temperature
- form
- clear liquid
- pka
- 14.96±0.40(Predicted)
- color
- Colorless to Almost colorless
- InChI
- InChI=1S/C8H14O3/c1-11-8(10)6-2-4-7(9)5-3-6/h6-7,9H,2-5H2,1H3/t6-,7-
- InChIKey
- HYDYVXROZHFTGB-LJGSYFOKSA-N
- SMILES
- [C@@H]1(C(OC)=O)CC[C@@H](O)CC1
- CAS DataBase Reference
- 6125-57-1
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Safety
- HS Code
- 2918199890
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
TCI Chemical
- Product number
- M1991
- Product name
- Methyl trans-4-Hydroxycyclohexanecarboxylate
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $43
- Updated
- 2025/07/31
TCI Chemical
- Product number
- M1991
- Product name
- Methyl trans-4-Hydroxycyclohexanecarboxylate
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $214
- Updated
- 2025/07/31
TRC
- Product number
- M323865
- Product name
- Methylrans-4-Hydroxycyclohexanecarboxylate
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
AK Scientific
- Product number
- 8254AL
- Product name
- Methyl trans-4-Hydroxycyclohexanecarboxylate
- Packaging
- 1g
- Price
- $91
- Updated
- 2021/12/16
AK Scientific
- Product number
- 8254AL
- Product name
- Methyl trans-4-Hydroxycyclohexanecarboxylate
- Packaging
- 5g
- Price
- $157
- Updated
- 2021/12/16
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trans-Methyl4-hydroxycyclohexanecarboxylate Chemical Properties,Usage,Production
Synthesis
99-76-3
3618-03-9
Example 1: To a Parr autoclave reactor was added 150 mL of methanol followed by 25 g of methyl 4-hydroxybenzoate (nipagin methyl ester). After displacing the air in the reactor with nitrogen, 2.5 g of 5% rhodium/alumina catalyst was added. The reaction mixture was pressurized to 3.74 MPa under hydrogen atmosphere and reacted for 18 hours under continuous shaking. Upon completion of the reaction, the hydrogen was again replaced with nitrogen and the reaction mixture was filtered through a diatomaceous earth pad to separate the catalyst. The diatomaceous earth pad was washed with methanol, taking care to avoid drying the catalyst. All filtrates were combined and methanol was removed by distillation under reduced pressure at about 40 °C. The residue was dissolved in 200 mL of ether and 3 g of anhydrous potassium carbonate was added. The precipitated alumina and potassium carbonate were removed by diatomaceous earth filtration and washed with ether. After combining the filtrates, the solvent was removed by distillation under reduced pressure to give the crude product. The crude product was purified by a Kugelrohr short-range distillation apparatus at 80-100 °C/1 mmHg to give 25.0 g (98% yield) of the colorless oily liquid methyl 4-hydroxycyclohexanecarboxylate. The product was characterized by 1H NMR (CDCl3, 60 MHz): δ 3.85 (s, 1H), 3.65 (s, 3H), 2.50-1.20 (m, 10H).
References
[1] Canadian Journal of Chemistry, 1982, vol. 60, p. 1996 - 2001
[2] Journal of Organic Chemistry, 1991, vol. 56, # 5, p. 1758 - 1763
[3] Bioorganic and Medicinal Chemistry, 2005, vol. 13, # 23, p. 6309 - 6323
[4] Bulletin de la Societe Chimique de France, 1970, p. 556 - 562
[5] Bulletin de la Societe Chimique de France, 1969, p. 781 - 787
trans-Methyl4-hydroxycyclohexanecarboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from trans-Methyl4-hydroxycyclohexanecarboxylate manufacturers
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
- Product
- Methyl 4-hydroxycyclohexanecarboxylate 6125-57-1
- Price
- US $3.00-9.00/KG
- Min. Order
- 0.1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2025-06-24
Pharmahands (Taizhou) Co., Ltd.
- Product
- trans-Methyl4-hydroxycyclohexanecarboxylate 6125-57-1
- Price
- US $0.00-0.00/Kg/Bag
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 100kg/month
- Release date
- 2020-10-30
Career Henan Chemical Co
- Product
- trans-Methyl4-hydroxycyclohexanecarboxylate 6125-57-1
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- JD 755
- Release date
- 2019-09-01
6125-57-1, trans-Methyl4-hydroxycyclohexanecarboxylateRelated Search:
4-METHOXY-3-BUTEN-2-ONE
trans-4-Methycyclohexyl isocyanate
p-Coumaric acid
TRANS-4-HYDROXYCYCLOHEXANECARBOXYLIC ACID
trans-4-Methylcyclohexyl amine
trans-4-MethoxycyclohexanaMine HCl
trans-4-Methylcyclohexylamine hydrochloride
METHYL 4-HYDROXYCYCLOHEXANECARBOXYLATE