GLY-ARG-GLY-ASP-SER-PRO-LYS

ChemicalBook > CAS DataBase List > GLY-ARG-GLY-ASP-SER-PRO-LYS

GLY-ARG-GLY-ASP-SER-PRO-LYS

Product Name: GLY-ARG-GLY-ASP-SER-PRO-LYS
CAS No.: 111119-28-9
Chemical Name: GLY-ARG-GLY-ASP-SER-PRO-LYS
Synonyms: GRGDSPK;EMD 56574;GRGDSPK (EMD 56574);GLY-ARG-GLY-ASP-SER-PRO-LYS;H-GLY-ARG-GLY-ASP-SER-PRO-LYS-OH;GLY-ARG-GLY-ASP-SER-PRO-LYS ACETATE;GRGDSPK, FIBRONECTIN ATTACHMENT PEPTIDE;Gly-Arg-Gly-Asp-Ser-Pro-Lys >=97% (HPLC);glycyl- arginyl-glycyl-aspartyl-seryl-prolyl-lysine;Glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl-L-prolyl-L-lysine
CBNumber: CB1123649
Molecular Formula: C28H49N11O11
Formula Weight: 715.76
MOL File: 111119-28-9.mol

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GLY-ARG-GLY-ASP-SER-PRO-LYS Property

Density: 1.59±0.1 g/cm3(Predicted)
storage temp.: -20°C
form: Solid
pka: 3.60±0.21(Predicted)
color: White to off-white

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: G1269
Product name: Gly-Arg-Gly-Asp-Ser-Pro-Lys
Purity: ≥97% (HPLC)
Packaging: 1mg
Price: $312
Updated: 2024/03/01

American Custom Chemicals Corporation

Product number: PEP0001656
Product name: GRGDSPK
Purity: 95.00%
Packaging: 1MG
Price: $591.82
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: PEP0001656
Product name: GRGDSPK
Purity: 95.00%
Packaging: 5MG
Price: $762.3
Updated: 2021/12/16

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GLY-ARG-GLY-ASP-SER-PRO-LYS Chemical Properties,Usage,Production

Uses

Gly-Arg-Gly-Asp-Ser-Pro-Lys (RGD peptide) has been used-

as a blocking peptide to inhibit integrin-fibronectin binding
in adhesion assay performed on porcine trophectoderm to study the influence of TGFβ (transforming growth factor) on cell adhesion
for incubation of MC3T3-E1 osteoblast cells to determine its effect on cell adhesion measured by AFM (atomic force microscopy)
for the preparation of RGD.Flt23k.NR nanoparticles
to determine the involvement of RGD-integrin bonding in cell adhesion process

General Description

Gly-Arg-Gly-Asp-Ser-Pro-Lys is a RGD peptide. Naturally occurring RGD peptides, present in the ECM (extracellalar matrix) proteins, are involved in facilitating integrin-mediated cell adhesion to matrix proteins. RGD peptide is present as repeats in cell-adhesion protein, such as fibronectin and vitronectin. This tripeptide is recognized by cells by specific integrins (e.g. β1 , β3 , and β5 subunits), present on the cell surface and associated with the actin filament via the FA (focal adhesion)-complex.

Biochem/physiol Actions

Fibronectin analog that binds to integrins.

GLY-ARG-GLY-ASP-SER-PRO-LYS Preparation Products And Raw materials

Raw materials

Preparation Products

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GLY-ARG-GLY-ASP-SER-PRO-LYS Suppliers

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111119-28-9, GLY-ARG-GLY-ASP-SER-PRO-LYSRelated Search:

ARG-GLY-ASP-SER GLY-ARG-GLY-ASP-SER GLY-ARG-GLY-ASP ARG-GLY-ASP 1-ADAMANTANEACETYL-CYS-GLY-ARG-GLY-*ASP-SER-PRO-LYS GLY-ARG-ALA-ASP-SER-PRO-LYS acetyl-arginyl-glycyl-aspartyl-serinamide H-ALA-ALA-PRO-ALA-OH GLY-ARG-GLY-ASP-SER-PRO-LYS H-ALA-PRO-ALA-OH L-LYSINE ACETATE SALT

H-GLY-ARG-GLY-ASP-SER-PRO-LYS-OH

GRGDSPK

GRGDSPK, FIBRONECTIN ATTACHMENT PEPTIDE

GLY-ARG-GLY-ASP-SER-PRO-LYS

GLY-ARG-GLY-ASP-SER-PRO-LYS ACETATE

glycyl- arginyl-glycyl-aspartyl-seryl-prolyl-lysine

EMD 56574

L-Lysine, glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl-L-prolyl-

Gly-Arg-Gly-Asp-Ser-Pro-Lys >=97% (HPLC)

Glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl-L-prolyl-L-lysine

GRGDSPK (EMD 56574)

111119-28-9

C28H49N11O11

Extracellular Matrix

Extracellular Matrix Peptides and Proteins

Cytoskeleton and Extracellular Matrix

Cell Signaling and Neuroscience

BioChemical

Cell Biology

peptide