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GLY-ARG-GLY-ASP-SER-PRO-LYS

Product Name
GLY-ARG-GLY-ASP-SER-PRO-LYS
CAS No.
111119-28-9
Chemical Name
GLY-ARG-GLY-ASP-SER-PRO-LYS
Synonyms
GRGDSPK;EMD 56574;GRGDSPK (EMD 56574);GLY-ARG-GLY-ASP-SER-PRO-LYS;H-GLY-ARG-GLY-ASP-SER-PRO-LYS-OH;GLY-ARG-GLY-ASP-SER-PRO-LYS ACETATE;GRGDSPK, FIBRONECTIN ATTACHMENT PEPTIDE;Gly-Arg-Gly-Asp-Ser-Pro-Lys >=97% (HPLC);glycyl- arginyl-glycyl-aspartyl-seryl-prolyl-lysine;Glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl-L-prolyl-L-lysine
CBNumber
CB1123649
Molecular Formula
C28H49N11O11
Formula Weight
715.76
MOL File
111119-28-9.mol
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GLY-ARG-GLY-ASP-SER-PRO-LYS Property

Density 
1.59±0.1 g/cm3(Predicted)
storage temp. 
-20°C
form 
Solid
pka
3.60±0.21(Predicted)
color 
White to off-white
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
G1269
Product name
Gly-Arg-Gly-Asp-Ser-Pro-Lys
Purity
≥97% (HPLC)
Packaging
1mg
Price
$312
Updated
2024/03/01
American Custom Chemicals Corporation
Product number
PEP0001656
Product name
GRGDSPK
Purity
95.00%
Packaging
1MG
Price
$591.82
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PEP0001656
Product name
GRGDSPK
Purity
95.00%
Packaging
5MG
Price
$762.3
Updated
2021/12/16
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GLY-ARG-GLY-ASP-SER-PRO-LYS Chemical Properties,Usage,Production

Uses

Gly-Arg-Gly-Asp-Ser-Pro-Lys (RGD peptide) has been used-

  • as a blocking peptide to inhibit integrin-fibronectin binding
  • in adhesion assay performed on porcine trophectoderm to study the influence of TGFβ (transforming growth factor) on cell adhesion
  • for incubation of MC3T3-E1 osteoblast cells to determine its effect on cell adhesion measured by AFM (atomic force microscopy)
  • for the preparation of RGD.Flt23k.NR nanoparticles
  • to determine the involvement of RGD-integrin bonding in cell adhesion process

General Description

Gly-Arg-Gly-Asp-Ser-Pro-Lys is a RGD peptide. Naturally occurring RGD peptides, present in the ECM (extracellalar matrix) proteins, are involved in facilitating integrin-mediated cell adhesion to matrix proteins. RGD peptide is present as repeats in cell-adhesion protein, such as fibronectin and vitronectin. This tripeptide is recognized by cells by specific integrins (e.g. β1 , β3 , and β5 subunits), present on the cell surface and associated with the actin filament via the FA (focal adhesion)-complex.

Biochem/physiol Actions

Fibronectin analog that binds to integrins.

GLY-ARG-GLY-ASP-SER-PRO-LYS Preparation Products And Raw materials

Raw materials

Preparation Products

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GLY-ARG-GLY-ASP-SER-PRO-LYS Suppliers

PolyPeptide Laboratories GmbH
Tel
--
Fax
--
Email
info@polypeptide.de
Country
Germany
ProdList
408
Advantage
66

111119-28-9, GLY-ARG-GLY-ASP-SER-PRO-LYSRelated Search:


  • H-GLY-ARG-GLY-ASP-SER-PRO-LYS-OH
  • GRGDSPK
  • GRGDSPK, FIBRONECTIN ATTACHMENT PEPTIDE
  • GLY-ARG-GLY-ASP-SER-PRO-LYS
  • GLY-ARG-GLY-ASP-SER-PRO-LYS ACETATE
  • glycyl- arginyl-glycyl-aspartyl-seryl-prolyl-lysine
  • EMD 56574
  • L-Lysine, glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl-L-prolyl-
  • Gly-Arg-Gly-Asp-Ser-Pro-Lys >=97% (HPLC)
  • Glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl-L-prolyl-L-lysine
  • GRGDSPK (EMD 56574)
  • 111119-28-9
  • C28H49N11O11
  • Extracellular Matrix
  • Extracellular Matrix Peptides and Proteins
  • Cytoskeleton and Extracellular Matrix
  • Cell Signaling and Neuroscience
  • BioChemical
  • Cell Biology
  • peptide