ChemicalBook > CAS DataBase List > GLY-ARG-GLY-ASP-SER-PRO-LYS
GLY-ARG-GLY-ASP-SER-PRO-LYS
- Product Name
- GLY-ARG-GLY-ASP-SER-PRO-LYS
- CAS No.
- 111119-28-9
- Chemical Name
- GLY-ARG-GLY-ASP-SER-PRO-LYS
- Synonyms
- GRGDSPK;EMD 56574;GRGDSPK (EMD 56574);GLY-ARG-GLY-ASP-SER-PRO-LYS;H-GLY-ARG-GLY-ASP-SER-PRO-LYS-OH;GLY-ARG-GLY-ASP-SER-PRO-LYS ACETATE;GRGDSPK, FIBRONECTIN ATTACHMENT PEPTIDE;Gly-Arg-Gly-Asp-Ser-Pro-Lys >=97% (HPLC);glycyl- arginyl-glycyl-aspartyl-seryl-prolyl-lysine;Glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl-L-prolyl-L-lysine
- CBNumber
- CB1123649
- Molecular Formula
- C28H49N11O11
- Formula Weight
- 715.76
- MOL File
- 111119-28-9.mol
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GLY-ARG-GLY-ASP-SER-PRO-LYS Property
- Density
- 1.59±0.1 g/cm3(Predicted)
- storage temp.
- -20°C
- form
- Solid
- pka
- 3.60±0.21(Predicted)
- color
- White to off-white
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Safety
- WGK Germany
- 3
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- G1269
- Product name
- Gly-Arg-Gly-Asp-Ser-Pro-Lys
- Purity
- ≥97% (HPLC)
- Packaging
- 1mg
- Price
- $312
- Updated
- 2024/03/01
American Custom Chemicals Corporation
- Product number
- PEP0001656
- Product name
- GRGDSPK
- Purity
- 95.00%
- Packaging
- 1MG
- Price
- $591.82
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- PEP0001656
- Product name
- GRGDSPK
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $762.3
- Updated
- 2021/12/16
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GLY-ARG-GLY-ASP-SER-PRO-LYS Chemical Properties,Usage,Production
Uses
Gly-Arg-Gly-Asp-Ser-Pro-Lys (RGD peptide) has been used-
- as a blocking peptide to inhibit integrin-fibronectin binding
- in adhesion assay performed on porcine trophectoderm to study the influence of TGFβ (transforming growth factor) on cell adhesion
- for incubation of MC3T3-E1 osteoblast cells to determine its effect on cell adhesion measured by AFM (atomic force microscopy)
- for the preparation of RGD.Flt23k.NR nanoparticles
- to determine the involvement of RGD-integrin bonding in cell adhesion process
General Description
Gly-Arg-Gly-Asp-Ser-Pro-Lys is a RGD peptide. Naturally occurring RGD peptides, present in the ECM (extracellalar matrix) proteins, are involved in facilitating integrin-mediated cell adhesion to matrix proteins. RGD peptide is present as repeats in cell-adhesion protein, such as fibronectin and vitronectin. This tripeptide is recognized by cells by specific integrins (e.g. β1 , β3 , and β5 subunits), present on the cell surface and associated with the actin filament via the FA (focal adhesion)-complex.
Biochem/physiol Actions
Fibronectin analog that binds to integrins.
GLY-ARG-GLY-ASP-SER-PRO-LYS Preparation Products And Raw materials
Raw materials
Preparation Products
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GLY-ARG-GLY-ASP-SER-PRO-LYS Suppliers
- Tel
- --
- Fax
- --
- neo@neomps.com
- Country
- France
- ProdList
- 2083
- Advantage
- 71
111119-28-9, GLY-ARG-GLY-ASP-SER-PRO-LYSRelated Search:
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acetyl-arginyl-glycyl-aspartyl-serinamide
H-ALA-ALA-PRO-ALA-OH
GLY-ARG-GLY-ASP-SER-PRO-LYS
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L-LYSINE ACETATE SALT