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1-N-Boc-cis-1,4-cyclohexyldiamine

Product Name
1-N-Boc-cis-1,4-cyclohexyldiamine
CAS No.
247570-24-7
Chemical Name
1-N-Boc-cis-1,4-cyclohexyldiamine
Synonyms
1-N-Boc-cis-1,4-cycL;1-N-Boc-cis-1,4-Cyclohexyldiam;N-Boc-cis-1,4-cyclohexyldiaMine;N1-BOC-CIS-1,4-CYCLOHEXYLDIAMINE;cis-N-Boc-1,4-cyclohexanediaMine;N-Boc-cis-1,4-cyclohexanediamine;1-N-BOC-CIS-1,4-CYCLOHEXYLDIAMINE;Cis-N-Boc-cyclohexane-1,4-diamine;Cis-1N-Boc-cyclohexane-1,4-diaMine;cis-4-(Boc-amino)cyclohexylamine,97%
CBNumber
CB1123856
Molecular Formula
C11H22N2O2
Formula Weight
214.3
MOL File
247570-24-7.mol
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1-N-Boc-cis-1,4-cyclohexyldiamine Property

Boiling point:
322.1±31.0 °C(Predicted)
Density 
1.02±0.1 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
form 
powder
pka
12.44±0.40(Predicted)
color 
Off-white
Water Solubility 
Soluble in methanol, ethyl acetate and Slightly soluble in water.
InChI
InChI=1S/C11H22N2O2/c1-11(2,3)15-10(14)13-9-6-4-8(12)5-7-9/h8-9H,4-7,12H2,1-3H3,(H,13,14)/t8-,9+
InChIKey
FEYLUKDSKVSMSZ-DTORHVGOSA-N
SMILES
C(OC(C)(C)C)(=O)N[C@@H]1CC[C@H](N)CC1
CAS DataBase Reference
247570-24-7
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Safety

Hazard Codes 
Xi
HazardClass 
IRRITANT
HS Code 
2921309990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Usbiological
Product number
228891
Product name
1-N-Boc-cis-1,4-cyclohexyldiamine 98+%
Packaging
1g
Price
$196
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB56957
Product name
1-N-Boc-cis-1,4-cyclohexyldiamine
Packaging
1g
Price
$70
Updated
2021/12/16
SynQuest Laboratories
Product number
4H56-1-TW
Product name
cis-Cyclohexane-1,4-diamine, N-Boc protected
Purity
98%
Packaging
1g
Price
$90
Updated
2021/12/16
Matrix Scientific
Product number
032285
Product name
cis-tert-Butyl 4-aminocyclohexylcarbamate
Purity
95%
Packaging
5g
Price
$112
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB56957
Product name
1-N-Boc-cis-1,4-cyclohexyldiamine
Packaging
2g
Price
$112
Updated
2021/12/16
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1-N-Boc-cis-1,4-cyclohexyldiamine Chemical Properties,Usage,Production

Uses

cis-4-(Boc-amino)cyclohexylamine can be used in agrochemical, pharmaceutical and dyestuff field.

Synthesis

247568-84-9

247570-24-7

Step 4: To a solution of tert-butyl (cis-4-azido-cyclohexyl)-carbamate (6.3 g, 26 mmol) in methanol (100 mL) was added 5% Pd/C (Degussa type, 0.63 g) under argon protection. The reaction flask was sealed, evacuated and backfilled with hydrogen, and the process was repeated three times. The reaction mixture was stirred for 2 h at room temperature under an atmosphere of hydrogen at 1 atm. Upon completion of the reaction, the catalyst was removed by filtration through a diatomaceous earth pad and the filtrate was concentrated under reduced pressure. The residue was partitioned between ether (Et2O) and 1N hydrochloric acid (HCl) solution. The aqueous phase was separated and alkalized with sodium hydroxide solution to pH > 10, followed by extraction with ethyl acetate (EtOAc, 2 × 100 mL). The organic phases were combined, washed with saturated sodium chloride solution (brine), dried over anhydrous sodium sulfate (Na2SO4), filtered and concentrated under reduced pressure to afford the white solid product (tert-butyl cis-4-amino-cyclohexyl)-carbamate (3.6 g, 64% yield). Mass spectrometry (MS) analysis showed (M+H)+ = 215.6.

References

[1] Patent: US2005/54626, 2005, A1. Location in patent: Page/Page column 48
[2] Patent: EP1683795, 2006, A1. Location in patent: Page/Page column 14; 15
[3] Patent: US2005/20639, 2005, A1. Location in patent: Page 14 - 15

1-N-Boc-cis-1,4-cyclohexyldiamine Preparation Products And Raw materials

Raw materials

Preparation Products

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1-N-Boc-cis-1,4-cyclohexyldiamine Suppliers

China 124 Europe 1 India 3 United Kingdom 5 United States 20 Global 153
Alfa Aesar
Tel
--
Fax
--
Email
tech@alfa.com
Country
India
ProdList
6905
Advantage
58
A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
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View Lastest Price from 1-N-Boc-cis-1,4-cyclohexyldiamine manufacturers

Career Henan Chemical Co
Product
1-N-Boc-cis-1,4-cyclohexyldiamine 247570-24-7
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2019-12-30

247570-24-7, 1-N-Boc-cis-1,4-cyclohexyldiamineRelated Search:

Nylon 6/6 trans-1,4-Diaminocyclohexane Cyclohexa-1,4-diene 1,2-Diaminocyclohexane (+/-)-trans-1,2-Diaminocyclohexane 1,4-Cyclohexanedione Hexamethylenediamine N-Boc-1,4-cyclohexanediamine CIS-1,4-CYCLOHEXANEDIAMINE 2-(1-amino-4-(tert-butoxycarbonylamino)cyclohexyl)acetic acid 1-N-Boc-cis-1,2-cyclohexyldiamine 4-(N-T-BUTOXYCARBONYLAMINO)CYCLOHEXYLISOCYANIDE 1-N-Boc-cis-1,4-cyclohexyldiamine 1, 1-ACCH(4-AMINO-BOC)-OME BOC-(4-CIS/TRANS)-1, 1-ACCH(4-AMINO-FMOC) BOC-CIS-1,4-AMINO-1-CYCLOHEXYL ACETIC ACID FMOC-1, 1-ACCH(4-AMINO-BOC) BOC-CIS-1,4-AMINO-1-CYCLOHEXANE CARBOXYLIC ACID

  • 1-N-BOC-CIS-1,4-CYCLOHEXYLDIAMINE
  • CIS-(4-AMINO-CYCLOHEXYL)-CARBAMIC ACID TERT-BUTYL ESTER
  • Carbamic acid, (cis-4-aminocyclohexyl)-, 1,1-dimethylethyl ester (9CI)
  • 1-N-Boc-cis-1,4-Cyclohexyldiam
  • cis tert-Butyl 4-aminocyclohexylcarbamate
  • Cis-(4-Amino-cyclohexyl)-carbamic acid
  • cis-Cyclohexane-1,4-diamine, N-BOC protected
  • tert-Butyl (cis-4-aminocyclohex-1-yl)carbamate, cis-1,4-Diaminocyclohexane, N-BOC protected
  • (4-{[(tert-butoxy)carbonyl]aMino}cyclohexyl)azanylidene
  • cis-N-tert-Butoxycarbonyl-1,4-cyclohexanediaMine
  • N-Boc-cis-1,4-cyclohexyldiaMine
  • TERT-BUTYL CIS-4-AMINOCYCLOHEXYLCARBAMATE
  • N1-BOC-CIS-1,4-CYCLOHEXYLDIAMINE
  • CarbaMic acid, N-(cis-4-aMinocyclohexyl)-, 1,1-diMethylethyl ester
  • cis-4-(Boc-aMino)cyclohexylaMine, 97%
  • cis-Cyclohexane-1,4-diamine, 1-BOC protected
  • tert-Butyl (cis-4-aminocyclohex-1-yl)carbamate, cis-1,4-Diaminocyclohexane, 1-BOC protected
  • cis-N-Boc-1,4-cyclohexanediaMine
  • Cis-1N-Boc-cyclohexane-1,4-diaMine
  • (E)-tert-butyl hydrogen ((1s,4s)-4-aminocyclohexyl)carbonimidate
  • Cis-N-Boc-cyclohexane-1,4-diamine
  • N-tert-Butoxycarbonyl-1,4-cyclohexanediamine
  • 1-N-Boc-Cis-1,4-Cyclohexyldiamine 98%
  • Carbamic acid, (cis-4-aminocyclohexyl)-, 1,1-dimethylethyl ester
  • N-(4-aminocyclohexyl)carbamic acid tert-butyl ester
  • 1-N-Boc-cis-1,4-cycL
  • cis-4-(Boc-amino)cyclohexylamine,97%
  • N-Boc-cis-1,4-cyclohexanediamine
  • 247570-24-7
  • N-BOC