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ALPHA-CGRP (8-37) (RAT)

Product Name
ALPHA-CGRP (8-37) (RAT)
CAS No.
129121-73-9
Chemical Name
ALPHA-CGRP (8-37) (RAT)
Synonyms
CGRP 8-37 (RAT);Rat CGRP-(8-37);PubChem ID: 90479762;RAT CGRP-(8-37)?, >98%;ALPHA-CGRP (8-37) (RAT);a-CGRP (8-37) (Mouse, rat);α-CGRP (8-37) (mouse, rat);Rat CGRP-(8-37) (TFA salt);Alpha-CGRP (8-37) (mouse, rat);VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF-NH2
CBNumber
CB1142835
Molecular Formula
C138H224N42O41
Formula Weight
3127.51
MOL File
129121-73-9.mol
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ALPHA-CGRP (8-37) (RAT) Property

Density 
1.47±0.1 g/cm3(Predicted)
storage temp. 
-20°C, protect from light
solubility 
H2O : 50 mg/mL (15.99 mM; Need ultrasonic)
form 
Solid
color 
White to off-white
Water Solubility 
Soluble to 1 mg/ml in water
Sequence
H-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asp-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Glu-Ala-Phe-OH
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
1169
Product name
CGRP8-37(rat)
Packaging
500U
Price
$342
Updated
2021/12/16
ChemScene
Product number
CS-7927
Product name
RatCGRP-(8-37)
Purity
98.54%
Packaging
1mg
Price
$348
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC109404
Product name
Alpha-CGRP (8-37) (mouse, rat) trifluoroacetate salt
Packaging
1mg
Price
$393
Updated
2021/12/16
ApexBio Technology
Product number
B5066
Product name
CGRP8-37(rat)
Packaging
500ug
Price
$497
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
BIO0000313
Product name
CALCITONIN GENE RELATED PEPTIDE (CGRP) (8-37)-RAT
Purity
95.00%
Packaging
0.5MG
Price
$650.27
Updated
2021/12/16
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ALPHA-CGRP (8-37) (RAT) Chemical Properties,Usage,Production

Uses

Rat CGRP-(8-37) (VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF) is a highly selective CGRP receptor antagonist.

in vivo

CGRP-(8-37) is effective in alleviating mechanical and thermal allodynia in a dose-dependent manner. The 50 nM dose is most efficacious for both forelimb and hindlimb responses. The period of efficacy is 10 min to onset for a duration of 20 min. Post-drug washout responses are not statistically significant compared to pre-drug responses[1]. Intrathecal administration of 5 nmol or 10 nmol of CGRP-(8-37), but not 1 nmol, induces a significant increase in hindpaw withdrawal latency. Intrathecal administration of CGRP-(8-37) not only reverses the SP-induced decrease in latency to both withdrawal responses but also mediates a significant increase in response latency compared to basal levels[2].

storage

Store at -20°C

References

[1] Bennett AD, et al. Alleviation of mechanical and thermal allodynia by CGRP(8-37) in a rodent model of chroniccentral pain. Pain. 2000 May;86(1-2):163-75. DOI:10.1016/s0304-3959(00)00242-6
[2] Yu LC, et al. The calcitonin gene-related peptide antagonist CGRP8-37 increases the latency to withdrawalresponses in rats. Brain Res. 1994 Aug 8;653(1-2):223-30. DOI:10.1016/0006-8993(94)90393-x

ALPHA-CGRP (8-37) (RAT) Preparation Products And Raw materials

Raw materials

Preparation Products

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ALPHA-CGRP (8-37) (RAT) Suppliers

China 83 France 1 Switzerland 1 United Kingdom 3 United States 14 USA 1 Global 103
NeoMPS SA
Tel
--
Fax
--
Email
neo@neomps.com
Country
France
ProdList
2083
Advantage
71
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View Lastest Price from ALPHA-CGRP (8-37) (RAT) manufacturers

Career Henan Chemical Co
Product
ALPHA-CGRP (8-37) (RAT) 129121-73-9
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2020-02-13

129121-73-9, ALPHA-CGRP (8-37) (RAT)Related Search:

H-LEU-LEU-HIS-ASP-LYS-GLY-LYS-SER-ILE-GLN-ASP-LEU-ARG-ARG-ARG-PHE-PHE-LEU-HIS-HIS-LEU-ILE-ALA-GLU-ILE-HIS-THR-ALA-NH2 11-Dideuterolinoleic acid Met-RANTES (human) IKKγ NBD Inhibitory Peptide GALANIN-(2-13)-GLU-HIS-(PRO)3-(ALA-LEU)2-ALA-AMIDE RAGE antagonist peptide VAL-GLY-SER-GLU [TYR22]-ALPHA-CGRP (22-37), RAT,TYR-ALPHA-CGRP (23-37) (RAT) [TYR0]-ALPHA-CGRP (28-37) (RAT),(TYR27)-ALPHA-CGRP (27-37) (RAT) ALPHA-CGRP (30-37) (RAT) ALPHA-CGRP (29-37) (RAT) ALPHA-CGRP (32-37) (RAT) ALPHA-CGRP (31-37) (RAT) ALPHA-CGRP (33-37) (RAT) ALPHA-CGRP (8-37) (RAT)

  • H-VAL-THR-HIS-ARG-LEU-ALA-GLY-LEU-LEU-SER-ARG-SER-GLY-GLY-VAL-VAL-LYS-ASP-ASN-PHE-VAL-PRO-THR-ASN-VAL-GLY-SER-GLU-ALA-PHE-NH2
  • CALCITONIN GENE RELATED PEPTIDE (8-37) RAT
  • ALPHA-CALCITONIN GENE-RELATED PEPTIDE (8-37) (RAT)
  • ALPHA-CGRP (8-37) (RAT)
  • VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF-NH2
  • VAL-THR-HIS-ARG-LEU-ALA-GLY-LEU-LEU-SER-ARG-SER-GLY-GLY-VAL-VAL-LYS-ASP-ASN-PHE-VAL-PRO-THR-ASN-VAL-GLY-SER-GLU-ALA-PHE-NH2
  • ALA-CYS-ASP-THR-ALA-THR-CYS-VAL-THR-HIS-ARG-LEU-ALA-GLY-LEU-LEU-SER-ARG-SER-GLY-GLY-VAL-VAL-LYS-ASN-ASN-PHE-VAL-PRO-THR-ASN-VAL-GLY-SER-LYS-ALA-PHE-NH2: ACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAF-NH2DISULFIDE BRIDGE CYS2-CYS7
  • α-CGRP (8-37) (mouse, rat)
  • α-CGRP (8-37) (canine, Mouse, rat) Calcitonin Gene-Related Peptide I (8-37) (canine, Mouse, rat), CGRP-I (8-37) (canine, Mouse, rat)
  • a-CGRP (8-37) (Mouse, rat)
  • Calcitonin Gene-Related Peptide I (8-37) (canine, Mouse, rat), CGRP-I (8-37) (canine, Mouse, rat), Calcitonin Gene-Related Peptide I (8-37) (Mouse, rat), CGRP-I (8-37) (Mouse, rat)
  • Rat CGRP-(8-37),VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF, >98%
  • RAT CGRP-(8-37)?, >98%
  • PubChem ID: 90479762
  • Alpha-CGRP (8-37) (mouse, rat)
  • α-CGRP (8-37) (mouse, rat),Calcitonin Gene-Related Peptide I (8-37) (mouse, rat), CGRP-I (8-37) (mouse, rat)
  • α-CGRP (8-37) (mouse, rat)|Calcitonin Gene Related Peptide (8-37),rat
  • CGRP 8-37 (RAT)
  • Rat CGRP-(8-37)
  • Calcitonin Gene Related Peptide (CGRP) (8-37), rat
  • Biotinyl-Ala-Cys-Asp-Thr-Ala-Thr-Cys-Val-Thr-His-Arg-Leu-Ala-GlyLeu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asn-Asn-Phe-Val-Pro-ThrAsn-Val-Gly-Ser-Lys-Ala-Phe-NH2trifluoroacetatesalt(Disulfidebond)
  • Alpha-CGRP (8-37) (mouse, rat) trifluoroacetate salt
  • Rat CGRP-(8-37)，VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF
  • α-CGRP (8-37) (canine, Mouse, rat) Calcitonin Gene-Related Peptide I (8-37) (canine, Mouse, rat), CGRP-I (8-37) (canine, Mouse, rat)
  • α-CGRP (8-37) (mouse, rat) trifluoroacetate salt
  • 8-37-α-Calcitonin gene-related peptide (human reduced), 25-L-aspartic acid-35-L-glutamic acid-
  • Rat CGRP-(8-37) (TFA salt)
  • ALA-CYS-ASP-THR-ALA-THR-CYS-VAL-THR-HIS-ARG-LEU-ALA-GLY-LEU-LEU-SER-ARG-SER-GLY-GLY-VAL-VAL-LYS-ASN-ASN-PHE-VAL-PRO-THR-ASN-VAL-
  • Calcitonin Gene Related Peptide (8-37), rat、Rat CGRP-(8-37)
  • (S)-4-((S)-2-(2-((S)-2-((S)-2-((2S,3R)-2-((S)-1-(L-Valyl-L-threonyl-L-histidyl-L-arginyl-L-leucyl-L-alanylglycyl-L-leucyl-L-leucyl-L-seryl-L-arginyl-L-serylglycylglycyl-L-valyl-L-valyl-L-lysyl-L-aspartyl-L-asparaginyl-L-phenylalanyl-L-valyl)pyrrolidine-2-carboxamido)-3-hydroxybutanamido)-4-amino-4-oxobutanamido)-3-methylbutanamido)acetamido)-3-hydroxypropanamido)-5-(((S)-1-(((S)-1-amino-1-oxo-3-phenylpropan-2-yl)amino)-1-oxopropan-2-yl)amino)-5-oxopentanoic acid
  • VAL-THR-HIS-ARG-LEU-ALA-GLY-LEU-LEU-SER-ARG-SER-GLY-GLY-VAL-VAL-LYS-ASP-ASN-PHE-VAL-PRO-THR-ASN-VAL-GLY-SER-GLU-ALA-PHE-NH2
  • 129121-73-9
  • C138H224N42O41
  • Peptide
  • Calcitonin and CGRP receptor