ChemicalBook > CAS DataBase List > Z-ORN(BOC)-OH

Z-ORN(BOC)-OH

Product Name
Z-ORN(BOC)-OH
CAS No.
7733-29-1
Chemical Name
Z-ORN(BOC)-OH
Synonyms
NSC 336232;Z-ORN(BOC)-OH;CBZ-ORN(BOC)-OH;Z-L-ORN(BOC)-OH;Z-ORNITHINE(BOC)-OH;Z-N-S-BOC-L-ORNITHINE;Z-Orn(Boc)-Oh7733-29-1;Z-ORN(BOC)-OH USP/EP/BP;Z-N-DELTA-BOC-L-ORNITHINE;N-α-Z-N-δ-Boc-L-ornithine
CBNumber
CB1142941
Molecular Formula
C18H26N2O6
Formula Weight
366.41
MOL File
7733-29-1.mol
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Z-ORN(BOC)-OH Property

Melting point:
97-103℃
Boiling point:
579.1±50.0 °C(Predicted)
Density 
1.193±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
3.94±0.21(Predicted)
form 
Solid
Appearance
White to off-white Solid
CAS DataBase Reference
7733-29-1
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene
Product number
CS-WAA0071
Product name
NSC336232
Purity
99.91%
Packaging
100g
Price
$454
Updated
2021/12/16
Iris Biotech GmbH
Product number
ZAA1166
Product name
Z-L-Orn(Boc)-OH
Packaging
25g
Price
$459
Updated
2021/12/16
Activate Scientific
Product number
AS102907
Product name
N5-Boc-N2-Cbz-L-ornithine
Purity
95% ee
Packaging
100g
Price
$1028
Updated
2021/12/16
ChemScene
Product number
CS-WAA0071
Product name
NSC336232
Purity
99.91%
Packaging
5g
Price
$50
Updated
2021/12/16
ChemScene
Product number
CS-WAA0071
Product name
NSC336232
Purity
99.91%
Packaging
10g
Price
$80
Updated
2021/12/16
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Z-ORN(BOC)-OH Chemical Properties,Usage,Production

Synthesis

13650-49-2

501-53-1

7733-29-1

To a stirred solution of δ-Boc-L-ornithine (0.5 g, 2.15 mmol, 1 eq.) dissolved in 5% aqueous NaHCO3 (30 mL) was slowly added benzyl chloroformate (0.4 mL, 2.80 mmol, 1.3 eq.) at room temperature. The reaction mixture was stirred continuously for 12 hours at room temperature. Upon completion of the reaction, extraction was performed by adding ether (20 mL) to remove unreacted benzyl chloroformate. The aqueous phase was adjusted to pH 1 with aqueous 6N hydrochloric acid and subsequently extracted with dichloromethane (50 mL x 3). The organic phases were combined, dried with anhydrous MgSO4, filtered and concentrated under reduced pressure to afford the target compound N-benzyloxycarbonyl-N'-tert-butoxycarbonyl-L-ornithine (Compound 13) as a colorless solid (0.71 g) in 90% yield.

References

[1] European Journal of Medicinal Chemistry, 2018, vol. 149, p. 122 - 128
[2] Helvetica chimica acta, 1966, vol. 49, # 3, p. 1013 - 1022
[3] Patent: US2004/6062, 2004, A1. Location in patent: Page/Page column 42
[4] FEBS Journal, 2013, vol. 280, # 8, p. 1807 - 1817

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Raw materials

Preparation Products

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View Lastest Price from Z-ORN(BOC)-OH manufacturers

Career Henan Chemical Co
Product
Z-ORN(BOC)-OH 7733-29-1
Price
US $1.00/KG
Min. Order
1KG
Purity
98% HPLC
Supply Ability
10 tons
Release date
2020-03-04

7733-29-1, Z-ORN(BOC)-OHRelated Search:


  • CBZ-ORN(BOC)-OH
  • N-ALPHA-BENZYLOXYCARBONYL-N-DELTA-BOC-L-ORNITHINE
  • N-ALPHA-BENZYLOXYCARBONYL-N-DELTA-T-BUTYLOXYCARBONYL-L-ORNITHINE
  • N-ALPHA-BENZYLOXYCARBONYL-N-DELTA-TERT-BUTYLOXYCARBONYL-L-ORNITHINE
  • N-ALPHA-CARBOBENZOXY,N-DELTA-T-BUTOXYCARBONYL-L-ORNITHINE
  • N-ALPHA-CBZ-N-DELTA-T-BOC-L-ORNITHINE
  • Z-N-S-BOC-L-ORNITHINE
  • Z-N-DELTA-BOC-L-ORNITHINE
  • Z-ORN(BOC)-OH
  • Z-ORNITHINE(BOC)-OH
  • Z-L-ORN(BOC)-OH
  • N-α-Z-N-δ-Boc-L-ornithine
  • Z-Orn(Boc)-Oh7733-29-1
  • Nα-Cbz-Nδ-Boc-L-ornithine
  • N2-Benzyloxycarbonyl-N5-tert-butoxycarbonyl-L -ornithine
  • N-.ALPHA.-CBZ-N-.DELTA.-BOC-L-ORNITHINE
  • (S)-12,12-dimethyl-3,10-dioxo-1-phenyl-2,11-dioxa-4,9-diazatridecane-5-carboxylic acid
  • L-Ornithine, N5-[(1,1-diMethylethoxy)carbonyl]-N2-[(phenylMethoxy)carbonyl]-
  • (S)-2-(((Benzyloxy)carbonyl)aMino)-5-((tert-butoxycarbonyl)aMino)pentanoic acid
  • Cbz-Orn(Boc)-OH, Nα-Cbz-Nδ-Boc-L-ornithine
  • N-Benzyloxycarbonyl-N'-(tert-butoxycarbonyl)-L-ornithine
  • 5-[(2-methylpropan-2-yl)oxycarbonylamino]-2-(phenylmethoxycarbonylamino)pentanoic acid
  • NSC 336232
  • N5-Boc-N2-Cbz-L-ornithine
  • -cyclypropyl-DL-phenylglycinamide
  • -isopropyl-DL-phenylglycinamide
  • -propyl-DL-phenylglycinamide
  • -tert-Butyl-DL-phenylglycinamide
  • -Cyclypentyl-DL-phenylglycinamide
  • (2S)-2-{[(benzyloxy)carbonyl]amino}-5-{[(tert-butoxy)carbonyl]amino}pentanoic acid
  • 5-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]-2-(phenylmethoxycarbonylamino)pentanoic acid
  • 5-[(2-methylpropan-2-yl)oxycarbonylamino]-2-(phenylmethoxycarbonylamino)pentanoicaci
  • Z-ORN(BOC)-OH USP/EP/BP
  • 7733-29-1
  • Ornithine [Org]
  • Amino Acid Derivatives