Fmoc-Orn(Boc)-OH

Product Name: Fmoc-Orn(Boc)-OH
CAS No.: 109425-55-0
Chemical Name: Fmoc-Orn(Boc)-OH
Synonyms: FMOC-ORN(BOC)-OH;FMOC-ORN(BOC);FMOC-L-ORN(BOC);FMOC-L-ORN(BOC)-OH;(S)-2-((((9H-fluoren-9-yl)Methoxy)carbonyl)aMino)-5-((tert-butoxycarbonyl)aMino)pentanoic acid;Ndelta L;CAS:109425-55-0;FMOC-ORN(BOT)-OH;RARECHEM EM WB 0176;FMOC-L-ORN(TBOC)-OH
CBNumber: CB2489395
Molecular Formula: C25H30N2O6
Formula Weight: 454.52
MOL File: 109425-55-0.mol

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Fmoc-Orn(Boc)-OH Property

Melting point:: 111-115℃
Boiling point:: 679.0±55.0 °C(Predicted)
Density: 1.226±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: soluble in Methanol
form: powder to crystal
pka: 3.85±0.21(Predicted)
color: White to Almost white
optical activity: Consistent with structure
BRN: 4772025
InChIKey: JOOIZTMAHNLNHE-NRFANRHFSA-N
SMILES: C(O)(=O)[C@H](CCCNC(OC(C)(C)C)=O)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
CAS DataBase Reference: 109425-55-0(CAS DataBase Reference)

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Safety

Safety Statements: 22-24/25
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29242990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 8.52015
Product name: Fmoc-Orn(Boc)-OH
Purity: Novabiochem?
Packaging: 5G
Price: $110
Updated: 2025/07/31

Sigma-Aldrich

Product number: 8.52015
Product name: Fmoc-Orn(Boc)-OH
Purity: Novabiochem?
Packaging: 25G
Price: $418
Updated: 2025/07/31

Sigma-Aldrich

Product number: 47560
Product name: Fmoc-Orn(Boc)-OH
Purity: ≥96.0% (HPLC)
Packaging: 5G
Price: $215
Updated: 2025/07/31

TCI Chemical

Product number: B4184
Product name: Nδ-(tert-Butoxycarbonyl)-Nα-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-ornithine
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $97
Updated: 2025/07/31

Cayman Chemical

Product number: 30471
Product name: Fmoc-Orn(Boc)-OH
Packaging: 500mg
Price: $37
Updated: 2024/03/01

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Fmoc-Orn(Boc)-OH Chemical Properties,Usage,Production

Description

Fmoc-Orn(Boc)-OH is an ornithine-containing amino acid building block. It has been used to conjugate ornithine to GFP-labeled peptides, enhancing cell permeability when compared to unconjugated GFP-labeled peptides. This compound is useful in preparing cyclic peptides and special arginine derivates.

Chemical Properties

White powder

Uses

Fmoc-Orn(Boc)-OH is a biochemical reagent. It can be used as a biomaterial or organic compound in life science-related research.

Preparation

2 mmol L-Orn was weighted and dissolved in 15 ml of acetonitrile; 16 mmol Boc2O was dissolved in acetonitrile and added dropwise to an acetonitrile solution of ornithine, to react and generate a complex; 10 ml 20% sodium bicarbonate aqueous solution was added, and 2 g of anhydrous sodium carbonate and an appropriate amount of 8-hydroxyquinoline were added in batches; the mixture was stirred and reacted at room temperature for 4 hours to remove copper ions in the complex; then 2 mmol Fmoc-OSu was added to the aforesaid solution, followed by stirring at room temperature for 2 hours; the resultant was recrystallized with an ethyl acetate/petroleum ether mixed solvent, to obtain a peptide head intermediate Fmoc-Orn(Boc)-OH.

reaction suitability

Reaction type: Fmoc solid-phase peptide synthesis

Solubility in organics

DMF: 20 mg/ml, DMF:PBS (pH 7.2) (1:5): 0.16 mg/ml, DMSO: 10 mg/ml, Ethanol: 10 mg/ml

References

[1] PAUL A. WENDER. Oligocarbamate Molecular Transporters: Design, Synthesis, and Biological Evaluation of a New Class of Transporters for Drug Delivery[J]. Journal of the American Chemical Society, 2002, 124 45: 13382-13383. DOI: 10.1021/ja0275109
[2] AJAY KUMAR . Enhanced gene transfection efficiency by polyamidoamine (PAMAM) dendrimers modified with ornithine residues[J]. International Journal of Pharmaceutics, 2010, 392 1: Pages 294-303. DOI: 10.1016/j.ijpharm.2010.03.054

Fmoc-Orn(Boc)-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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Fmoc-Orn(Boc)-OH Suppliers

Americas 1 Australia 1 Belgium 2 Canada 1 China 245 Europe 4 France 3 Germany 9 India 11 Japan 7 Latvia 1 Poland 1 South Korea 1 Switzerland 6 The Netherlands 1 United Kingdom 12 United States 55 Global 361

Nextpeptide Inc

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View Lastest Price from Fmoc-Orn(Boc)-OH manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd

Product: Fmoc-L-Orn(Boc)-OH 109425-55-0
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1T+
Release date: 2023-09-27

Career Henan Chemical Co

Product: Nalpha-Fmoc-Ndelta-Boc-L-ornithine 109425-55-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20kg
Release date: 2018-08-15

109425-55-0, Fmoc-Orn(Boc)-OHRelated Search:

Nalpha-Fmoc-Ndelta-trityl-L-glutamine Fmoc-Lys(Boc)-OH N-(tert-Butoxycarbonyl)-L-alanine 9-Fluorenylmethyl chloroformate Fmoc-O-trityl-L-serine Boc-Aib-OH L-Fmoc-Aspartic acid alpha-tert-butyl ester L(+)-Ornithine hydrochloride L-Ornithine Fmoc-Asp(OtBu)-OH Fmoc-Phe-OH N-Boc-N'-nitro-L-arginine 1,1'-Carbonyldiimidazole Fmoc-OrnMe(Alloc)-OH FMOC-ORN(ALOC)-OH Fmoc-OSu FMOC-ORN(BOC)-OPFP Fmoc

N(α)-fmoc-N(delta)-boc-L-ornithine

N-DELTA-BOC-N-ALPHA-FMOC-L-ORNITHINE

RARECHEM EM WB 0176

N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-GAMMA-T-BUTYL-OXYCARBONYL-L-ORNITHINE

N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-DELTA-TERT-BUTYLOXYCARBONYL-L-ORNITHINE

N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-N-DELTA-T-BUTOXYCARBONYL-L-ORNITHINE

N-ALPHA-FMOC-N-DELTA-BOC-L-ORNITHINE

N-ALPHA-FMOC-N-DELTA-T-BOC-L-ORNITHINE

N-ALPHA-FMOC-N-DELTA-T-BUTYLOXYCARBONYL-L-ORNITHINE

N-ALPHA-FMOC-N-DELTA-TERT-BOC-L-ORNITHINE

(2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-5-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoic acid

FMOC-L-ORN(BOC)-OH

FMOC-L-ORN(TBOC)-OH

FMOC-L-ORN(BOC)

FMOC-(N-DELTA-BOC)-L-ORNITHINE

FMOC-N-BOC-L-ORNITHINE

FMOC-ORN(BOC)-OH

FMOC-ORNITHINE(BOC)-OH

N-tert-Butoxycarbonyl-N-9-fluorenylmethoxycarbonyl-L-ornithine

N-α-Boc-N-δ-Boc-L-ornithine

FMOC-ORN(BOC)-OH 98+%

nα-fmoc-nδ-boc-l-ornithine

FMOC-ORN(BOC)

FMOC-ORN(BOT)-OH

Fmoc-Orn(Boc)-OH [109425-55-0]

(2S)-5-{[(tert-butoxy)carbonyl]amino}-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pentanoic acid

NEPSILON-tert-Butoxycarbonyl-NALPHA-9-fluorenylmethoxycarbonyl-L-ornithine

L-ORNITHINE, N5-[(1,1-DIMETHYLETHOXY)CARBONYL]-N2-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-

FMoc-Orn(Boc)-OH N-α-Boc-N-δ-Boc-L-ornithine

Nδ-Boc-Nα-Fmoc-L-ornithine, Nα-Fmoc-Nδ-Boc-L-ornithine

N-ALPHA-FMOC-N-GAMMA-BOC-L-ORNITHINE

Nalpha-Fmoc-Ndelta-B

N-DELTA-Boc-N-ALFA-Fmoc-L-ornithine

Na-Fmoc-Nγ-Boc-L-ornithine ,98%

n-delta-boc-n--fmoc-l-ornithine

Fmoc-(Nd-Boc)-L-ornithine

(S)-2-((((9H-fluoren-9-yl)Methoxy)carbonyl)aMino)-5-((tert-butoxycarbonyl)aMino)pentanoic acid

N^d-Boc-N^a-FMoc-L-ornithine, 96%

FMoc-Ornithine(Boc)

Ndelta-(tert-Butoxycarbonyl)-Nalpha-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-ornithine

Fmoc-Orn(Boc)-OH >=96.0% (HPLC)

Nδ-(tert-Butoxycarbonyl)-Nα-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-ornithine

Nα-Fmoc-Nδ-Boc-L-ornithine≥ 99.5% (HPLC, Chiral purity)

(9H-Fluoren-9-yl)MethOxy]Carbonyl Orn(Boc)-OH

Nδ-(tert-Butoxycarbonyl)-Nα-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-ornithine &gt

Ndelta L

(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-5-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoicaci

Nalpha-Fmoc-Ndelta-Boc-L-ornithine USP/EP/BP

N5-Boc-N2-Fmoc-L-ornithine

Fmoc-Orn(Boc)-OH,96%

CAS:109425-55-0

FMOC-ORN(BOC)-OH 98%

Nα-Fmoc-Nδ-tbutyloxycarbonyl -L-ornithine

109425-55-0

Ornithine

Peptide Synthesis

Specialty Synthesis

Unnatural Amino Acid Derivatives