1-(1,8-dihydroxy-3-methyl-naphthalen-2-yl)ethanone
- Product Name
- 1-(1,8-dihydroxy-3-methyl-naphthalen-2-yl)ethanone
- CAS No.
- 3785-24-8
- Chemical Name
- 1-(1,8-dihydroxy-3-methyl-naphthalen-2-yl)ethanone
- Synonyms
- Nepodin;Musizin;Musizine;NSC 365795;NEPODIN (MUSIZIN);Nepodin, 10 mM in DMSO;2-Acetyl-3-methyl-1,8-naphthalenediol;Ethanone,1-(1,8-dihydroxy-3-methyl-2-naphthalenyl)-;1-(1,8-dihydroxy-3-methyl-naphthalen-2-yl)ethanone USP/EP/BP;Inhibitor,AMP-activated protein kinase,Musizin,Parasite,AMPK,Nepodin,inhibit
- CBNumber
- CB11458887
- Molecular Formula
- C13H12O3
- Formula Weight
- 216.23
- MOL File
- 3785-24-8.mol
1-(1,8-dihydroxy-3-methyl-naphthalen-2-yl)ethanone Property
- Melting point:
- 165-166℃ (methanol )
- Boiling point:
- 357.9±22.0 °C(Predicted)
- Density
- 1.285±0.06 g/cm3 (20 ºC 760 Torr)
- storage temp.
- 4°C, protect from light
- solubility
- Methanol: soluble
- form
- A solid
- pka
- 5.13±0.50(Predicted)
- color
- White to yellow
- InChI
- InChI=1S/C13H12O3/c1-7-6-9-4-3-5-10(15)12(9)13(16)11(7)8(2)14/h3-6,15-16H,1-2H3
- InChIKey
- DMLHPCALHMPJHS-UHFFFAOYSA-N
- SMILES
- C(=O)(C1=C(C)C=C2C(=C1O)C(O)=CC=C2)C
Safety
- WGK Germany
- WGK 3
- Storage Class
- 11 - Combustible Solids
- Hazard Classifications
- Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 27611
- Product name
- Nepodin
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $43
- Updated
- 2026/04/30
- Product number
- 27611
- Product name
- Nepodin
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $191
- Updated
- 2026/04/30
- Product number
- 27611
- Product name
- Nepodin
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $316
- Updated
- 2026/04/30
- Product number
- 27611
- Product name
- Nepodin
- Packaging
- 1mg
- Price
- $39
- Updated
- 2024/03/01
- Product number
- 27611
- Product name
- Nepodin
- Packaging
- 10mg
- Price
- $287
- Updated
- 2024/03/01
1-(1,8-dihydroxy-3-methyl-naphthalen-2-yl)ethanone Chemical Properties,Usage,Production
Chemical Properties
Pale yellow crystals, soluble in methanol, ethanol, ethyl acetate, insoluble in water, derived from the root of the Polygonaceae plant Rhizoma Cibotii or Rhizoma Nepalensis.
Uses
1-(1,8-Dihydroxy-3-methyl-naphthalen-2-yl)-ethanone is a naphthalene for proteomics research.
Definition
ChEBI: Nepodin is a member of naphthols.
in vivo
Nepodin (Musizin) (orally administration; 2-10 mg/kg; 4 weeks) improves the impaired glucose tolerance of db/db mice, also decreases an increase in plasma insulin concentration of db/db mice in a dose-dependent manner[2].
| Animal Model: | C57BL/KsJ-db/db mice[2] |
| Dosage: | 2 mg/kg; 10 mg/kg |
| Administration: | Orally administration; 2-10 mg/kg; 4 weeks |
| Result: | Had antihyperglycemic potential and improved insulin resistance. |
IC 50
Plasmodium
1-(1,8-dihydroxy-3-methyl-naphthalen-2-yl)ethanone Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1-(1,8-dihydroxy-3-methyl-naphthalen-2-yl)ethanone manufacturers
- Product
- Musizin 3785-24-8
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 10%
- Supply Ability
- 1000 kg
- Release date
- 2024-04-15
- Product
- 1-(1,8-dihydroxy-3-methyl-naphthalen-2-yl)ethanone 3785-24-8
- Price
- US $3.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1kg,5kg,50kg
- Release date
- 2020-01-18