1-BENZYLPIPERIDINE-4-CARBOXYLIC ACID
- Product Name
- 1-BENZYLPIPERIDINE-4-CARBOXYLIC ACID
- CAS No.
- 10315-07-8
- Chemical Name
- 1-BENZYLPIPERIDINE-4-CARBOXYLIC ACID
- Synonyms
- BUTTPARK 33\04-90;Bzl-isonipecotic acid;1-BENZYL-ISONIPECOTIC ACID;N-BENZYL-ISONIPECOTIC ACID;1-benzylpiperidin-4-carboxylic acid;1-BENZYLPIPERIDINE-4-CARBOXYLIC ACID;N-Benzylpiperidine-4-carboxylic acid;N-Benzyl-4-Piperidinecarboxylic acid;1-BENZYL-4-PIPERIDINE CARBOXYLIC ACID;1-N-Benzyl-pipeidine-4-carboxylic acid
- CBNumber
- CB1150793
- Molecular Formula
- C13H17NO2
- Formula Weight
- 219.28
- MOL File
- 10315-07-8.mol
1-BENZYLPIPERIDINE-4-CARBOXYLIC ACID Property
- Melting point:
- 169.0-170.5 °C
- Boiling point:
- 358.6±35.0 °C(Predicted)
- Density
- 1.165
- storage temp.
- 2-8°C
- form
- powder to crystal
- pka
- 4.02±0.20(Predicted)
- color
- White to Almost white
- CAS DataBase Reference
- 10315-07-8(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- B5826
- Product name
- 1-Benzylpiperidine-4-carboxylic Acid
- Packaging
- 1G
- Price
- $131
- Updated
- 2025/07/31
- Product number
- B5826
- Product name
- 1-Benzylpiperidine-4-carboxylic Acid
- Packaging
- 5G
- Price
- $436
- Updated
- 2025/07/31
- Product number
- B288993
- Product name
- 1-Benzylpiperidine-4-carboxylic Acid
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 4H56-1-6H
- Product name
- 1-Benzylpiperidine-4-carboxylic acid
- Purity
- 96%
- Packaging
- 1g
- Price
- $48
- Updated
- 2021/12/16
- Product number
- FB15438
- Product name
- 1-Benzyl-isonipecotic acid
- Packaging
- 1g
- Price
- $75
- Updated
- 2021/12/16
1-BENZYLPIPERIDINE-4-CARBOXYLIC ACID Chemical Properties,Usage,Production
Synthesis
24228-40-8
10315-07-8
(b) Synthesis of 1-benzyl-4-piperidinecarboxylic acid: 4N aqueous sodium hydroxide solution (35 mL) was added to a solution of ethyl 1-benzyl-4-piperidinecarboxylate (16.1 g, 65.1 mmol) in tetrahydrofuran (70 mL). The reaction mixture was stirred at room temperature and 1,4-dioxane (70 mL) was added and stirring was continued overnight. Upon completion of the reaction, the pH of the reaction solution was adjusted to 7 with 2 N hydrochloric acid. subsequently, the solvent was removed by distillation under reduced pressure. The obtained residue was suspended in ethanol and the solid was collected by filtration. Finally, the filtrate was concentrated under reduced pressure to afford 1-benzyl-4-piperidine carboxylic acid (13.6 g, 95% yield).
References
[1] Bioorganic and Medicinal Chemistry Letters, 2009, vol. 19, # 17, p. 4980 - 4983
[2] Patent: EP1500643, 2005, A1. Location in patent: Page 18
[3] Journal of Medicinal Chemistry, 2005, vol. 48, # 20, p. 6491 - 6503
[4] Helvetica Chimica Acta, 1997, vol. 80, # 5, p. 1528 - 1551
[5] Patent: US6020368, 2000, A
1-BENZYLPIPERIDINE-4-CARBOXYLIC ACID Preparation Products And Raw materials
Raw materials
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View Lastest Price from 1-BENZYLPIPERIDINE-4-CARBOXYLIC ACID manufacturers
- Product
- 1-BENZYLPIPERIDINE-4-CARBOXYLIC ACID 10315-07-8
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11
- Product
- 1-BENZYLPIPERIDINE-4-CARBOXYLIC ACID 10315-07-8
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1ton
- Release date
- 2018-08-08