Isonipecotic acid

Product Name: Isonipecotic acid
CAS No.: 498-94-2
Chemical Name: Isonipecotic acid
Synonyms: PIPERIDINE-4-CARBOXYLIC ACID;4-PIPERIDINECARBOXYLIC ACID;Inp-OH;H-INP-OH;H-PIC(4)-OH;h-dl-inp-oh;Isonipecotic aci;sonipecotic acid;ISONIPECOTIC ACID;AKOS BBS-00003783
CBNumber: CB7426775
Molecular Formula: C6H11NO2
Formula Weight: 129.16
MOL File: 498-94-2.mol

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Isonipecotic acid Property

Melting point:: >300 °C(lit.)
Boiling point:: 239.22°C (rough estimate)
Density: 1.1426 (rough estimate)
refractive index: 1.4587 (estimate)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: Water
form: Powder
pka: pK1:3.73(+1);pK2:10.72(0) (25°C)
color: White to faint pink-beige
Water Solubility: soluble
Merck: 14,5189
BRN: 112553
CAS DataBase Reference: 498-94-2(CAS DataBase Reference)
EPA Substance Registry System: 4-Piperidinecarboxylic acid (498-94-2)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-37/39
WGK Germany: 3
RTECS: NS5150000
TSCA: T
HazardClass: IRRITANT
HS Code: 29333999

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: I18008
Product name: Isonipecotic acid
Purity: 97%
Packaging: 25g
Price: $53.8
Updated: 2024/03/01

Sigma-Aldrich

Product number: I18008
Product name: Isonipecotic acid
Purity: 97%
Packaging: 100g
Price: $116
Updated: 2024/03/01

TCI Chemical

Product number: I0256
Product name: 4-Piperidinecarboxylic Acid
Purity: >98.0%(T)
Packaging: 25g
Price: $20
Updated: 2024/03/01

TCI Chemical

Product number: I0256
Product name: 4-Piperidinecarboxylic Acid
Purity: >98.0%(T)
Packaging: 100g
Price: $53
Updated: 2024/03/01

Alfa Aesar

Product number: A11795
Product name: Isonipecotic acid, 98%
Packaging: 25g
Price: $47.65
Updated: 2024/03/01

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Isonipecotic acid Chemical Properties,Usage,Production

Chemical Properties

white to faint pink-beige powder

Uses

A GABA-A receptor partial agonist

Synthesis Reference(s)

Synthesis, p. 623, 1984
Tetrahedron Letters, 35, p. 8783, 1994 DOI: 10.1016/S0040-4039(00)78497-8

Purification Methods

It crystallises from H2O or EtOH as needles. The hydrochloride recrystallises from H2O or aqueous HCl with m 293odec (also 298odec, 300odec). [Wibaut Recl Trav Chim Pays-Bas 63 141 1944, IR: Zacharius et al. J Am Chem Soc 76 2908 1954, Beilstein 22/1 V 244.]

Isonipecotic acid Preparation Products And Raw materials

Raw materials

Preparation Products

BENZYL 4-(BROMOMETHYL)TETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE N-BOC-ISONIPECOTIC ACID 4-PIPERIDINECARBOXYLIC ACID T-BUTYL ESTER HCL 1-METHYL-PIPERIDINE-4-CARBOXYLIC ACID 1-ACETYLISONIPECOTOYL CHLORIDE PHENYL(PIPERIDIN-4-YL)METHANONE 1-tert-Butoxycarbonyl-4-piperidinecarboxaldehyde 1-ACETYL-4-BENZOYLPIPERIDINE N-BOC-piperidine-4-carboxylic acid 4-(Boc-Aminomethyl)piperidine 6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole 1-Methylpiperidin-4-amine 1-(4-ACETYLPIPERIDINO)ETHAN-1-ONE 1-METHYLPIPERIDINE-4-CARBOXYLIC ACID HYDROCHLORIDE 1-Boc-4-(aminomethyl)piperidine 1-Acetyl-4-piperidinecarboxylic acid 4-Benzylpiperidine 4-N-BOC-Aminopiperidine 1-[(Benzyloxy)carbonyl]piperidine-4-carboxylic acid 4-Cyanopiperidine 1-Boc-4-cyanopiperidine 1-(PIPERIDIN-4-YLCARBONYL)PIPERIDINE

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Isonipecotic acid Suppliers

Americas 1 Belgium 2 Canada 4 China 403 Europe 4 France 2 Germany 13 India 65 Ireland 1 Italy 1 Japan 9 Singapore 1 Slovakia 1 South Korea 1 Switzerland 4 The Netherlands 1 Ukraine 2 United Kingdom 18 United States 63 Global 596

JIANGYIN RUISHIPHARM CO.,LIMITED

Tel: 0510-0510-66227179 18921203887
Fax: +86-0510-66227179 QQ:2200317867
Email: sales@ruishipharm.com
Country: China
ProdList: 751
Advantage: 58

Shanghai Taijilin Industrial Co., Ltd.

Tel: 021-021-50630626 18964684208
Fax: 021-50563898
Email: kate@tajilin.com
Country: China
ProdList: 1212
Advantage: 58

Terma Medicare India Pvt Ltd

Tel: 021-52530655 18930806002
Email: yuli@semsstar.com
Country: China
ProdList: 134
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006608290; 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40241
Advantage: 62

INTATRADE GmbH

Tel: +49 3493/605464
Fax: +49 3493/605470
Email: sales@intatrade.de
Country: Germany
ProdList: 3576
Advantage: 66

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15848
Advantage: 69

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30132
Advantage: 84

TAIYUAN RHF CO.,LTD.

Tel: +86 351 7031519
Fax: +86 351 7031519
Email: sales@RHFChem.com
Country: China
ProdList: 2341
Advantage: 56

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24539
Advantage: 81

498-94-2, Isonipecotic acidRelated Search:

2,2,6,6-Tetramethyl-4-piperidinol Citric acid Isonipecotic acid ethyl,ISONIPECOTIC ACID ETHYL ESTER Folic acid DROPERIDOL ISONIPECOTIC ACID, METHYL AND ETHYL ESTERS,Isonipecotic acid methyl Hyaluronic acid Triacetonediamine Haloperidol Ethyl 2-(Chlorosulfonyl)acetate Benzyl 4-hydroxy-1-piperidinecarboxylate Ascoric Acid Azido-PEG1-CH2CO2H 4-HYDROXY-3-METHYLBENZOIC ACID Hexahydroisonicotinamide 4-Pyrimidinecarboxylic acid 4,4-Piperidinediol hydrochloride PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER HYDROCHLORIDE

Isonipecotic acid, 4-Carboxypiperidine

4 - piperidine forMic acid

Isonipecotic aci

Isonipecotic acid, 99% 25GR

Piperidin-4-carboxylic acid

4-PIPERIDINECARBOXYLIC ACID FOR SYNTHESI

Piperidine-4-carboxylic acid or isonipecotic acid

AKOS BBS-00003783

DL-ISOPIPECOLINIC ACID

H-PIC(4)-OH

ISONIPECOTIC ACID

HEXAHYDROISONICOTINIC ACID

H-INP-OH

H-ISONICOT(H6)-OH

L-ISONIPECOTIC ACID

LABOTEST-BB LT00847733

4-hexahydroisonicotinicacid

acideisonipecotique

acidepiperidine-carboxylique-4

TIMTEC-BB SBB004231

4-CARBOXYPIPERIDINE

4-PIPERIDINECARBOXYLIC ACID

sonipecotic acid

DL-ISOPIPECOLINIC ACID / 4-PIPERIDINECARBOXYLIC ACID

Inp-OH

Isonipecotic acid≥ 99% (Titration)

4-Piperidinecarboxylic acid for synthesis

IsonipecoticAcid98%

4-PiperidinecarboxylicAcid/IsonipecoticAcid

(n)-piperidine-4-carboxylic acid

h-dl-inp-oh

Piperidine-4-carboxylic acid 98%

4-PIPERIDINECARBOXLIC ACID

PIPERIDINE-4-CARBOXYLIC ACID , ISONIPECOTIC ACID

PIPERIDIN-4-YLCARBOXYLIC ACID

ISONIPECOTIC ACID PIPERIDINE-4-CARBOXYLIC ACID

4-[(1-oxopropyl)phenylamino]-1-(phenylmethyl)-

4-Piperidinecarboxylic acid, Hexahydroisonicotinic acid

4-Piperidinecarboxylic acid ,98%

Piperidine-4-carbonic acid

Isonipecotic acid,99%

Isonipecotic acid , 97+%

4-acid piperidine

Isonipecotic acid, 99% 100GR

RARECHEM AH CK 0178

PIPERIDINE-4-CARBOXYLIC ACID

4-Piperidinecaboxylic Acid

DL-Isonipecotic acid

H-DL-Inp-OH~(+/-)-Piperidine-4-carboxylic acid

Hexahydroisonicotine acid

4-PiperidinecarboxylicAcid&gt

Isonipecotic acid ISO 9001：2015 REACH

4-Piperidinecarboxylic acid (9CI, ACI)

Avatrombopag Impurity 67

4-piperidinic acid

498-94-2

198-94-2

C23H28N2O3C2H2O4