Ethyl 4-piperidinecarboxylate
- Product Name
- Ethyl 4-piperidinecarboxylate
- CAS No.
- 1126-09-6
- Chemical Name
- Ethyl 4-piperidinecarboxylate
- Synonyms
- ETHYL PIPERIDINE-4-CARBOXYLATE;ETHYL ISONIPECOTATE;4-piperidinecarboxylate;PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER;H-Nip-OEt;H-DL-Inp-OEt;AKOS MSC-0737;RARECHEM AH CK 0180;TIMTEC-BB SBB004006;ETHYL ISONEPECOTATE
- CBNumber
- CB7231962
- Molecular Formula
- C8H15NO2
- Formula Weight
- 157.21
- MOL File
- 1126-09-6.mol
Ethyl 4-piperidinecarboxylate Property
- Boiling point:
- 204 °C(lit.)
- Density
- 1.02 g/mL at 25 °C(lit.)
- vapor pressure
- 39.4Pa at 25℃
- refractive index
- n20/D 1.459(lit.)
- Flash point:
- 176 °F
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- form
- Liquid
- pka
- 9.83±0.10(Predicted)
- color
- Clear colorless to slightly brown
- Water Solubility
- miscible
- BRN
- 118419
- LogP
- 1.15
- CAS DataBase Reference
- 1126-09-6(CAS DataBase Reference)
- NIST Chemistry Reference
- Ethyl piperidine-4-carboxylate(1126-09-6)
Safety
- Hazard Codes
- C,Xi
- Risk Statements
- 34-36/37/38
- Safety Statements
- 23-24/25-36-26
- RIDADR
- UN2735
- WGK Germany
- 3
- Hazard Note
- Irritant
- HS Code
- 29333999
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H227Combustible liquid
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P370+P378In case of fire: Use … for extinction.
P403+P235Store in a well-ventilated place. Keep cool.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- E33505
- Product name
- Ethyl isonipecotate
- Purity
- 98%
- Packaging
- 25g
- Price
- $51.3
- Updated
- 2024/03/01
- Product number
- E33505
- Product name
- Ethyl isonipecotate
- Purity
- 98%
- Packaging
- 100g
- Price
- $148
- Updated
- 2024/03/01
- Product number
- I0294
- Product name
- Ethyl 4-Piperidinecarboxylate
- Purity
- >98.0%(GC)
- Packaging
- 25mL
- Price
- $36
- Updated
- 2024/03/01
- Product number
- I0294
- Product name
- Ethyl 4-Piperidinecarboxylate
- Purity
- >98.0%(GC)
- Packaging
- 100mL
- Price
- $94
- Updated
- 2024/03/01
- Product number
- B20601
- Product name
- Ethyl isonipecotate, 98%
- Packaging
- 25g
- Price
- $40.65
- Updated
- 2024/03/01
Ethyl 4-piperidinecarboxylate Chemical Properties,Usage,Production
Chemical Properties
clear colorless to slightly brown liquid
Uses
Reactant for synthesis of:• ;SMN protein modulators1• ;β-aryl and β-amino-substituted aliphatic esters by rhodium catalyzed tandem double bond migration/conjugate addition2• ;Nitroethylenediamines by nucleophilic ring opening of nitroimidazolidinone3• ;RhoA inhibitors for cardiovascular disease therapy4• ;Saccharin derived Mannich bases as antimicrobials and antioxidants5Reactant for one-pot reductive amination and Suzuki-Miyaura cross coupling of formyl aryl and heteroaryl MIDA boronates6
Uses
Reactant for synthesis of SMN protein modulators and β-aryl and β-amino-substituted aliphatic esters by rhodium catalyzed tandem double bond migration/conjugate addition.
Uses
It is used as a reactant for synthesis of SMN protein modulators, β-aryl and β-amino-substituted aliphatic esters by rhodium catalyzed tandem double bond migration/conjugate addition, nitroethylenediamines by nucleophilic ring opening of nitroimidazolidinone. It is also involved in the reactions of RhoA inhibitors for cardiovascular disease therapy and saccharin derived Mannich bases as antimicrobials and antioxidants. It is employed as a reactant for one-pot reductive amination and Suzuki-Miyaura cross coupling of formyl aryl and heteroaryl MIDA boronates.
Synthesis Reference(s)
Tetrahedron Letters, 23, p. 193, 1982 DOI: 10.1016/S0040-4039(00)86783-0
Ethyl 4-piperidinecarboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Ethyl 4-piperidinecarboxylate manufacturers
- Product
- Ethyl 4-piperidinecarboxylate 1126-09-6
- Price
- US $8.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-03-29
- Product
- Ethyl piperidine-4-carboxylate 1126-09-6
- Price
- US $0.00/kg
- Min. Order
- 25kg
- Purity
- ≥98%
- Supply Ability
- Inquiry
- Release date
- 2022-10-28
- Product
- Ethyl piperidine-4-carboxylate 1126-09-6
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2023-12-21