3-FLUORO-N-METHOXY-N-METHYLBENZAMIDE
- Product Name
- 3-FLUORO-N-METHOXY-N-METHYLBENZAMIDE
- CAS No.
- 226260-01-1
- Chemical Name
- 3-FLUORO-N-METHOXY-N-METHYLBENZAMIDE
- Synonyms
- 3-FLUORO-N-METHOXY-N-METHYLBENZAMIDE;Benzamide, 3-fluoro-N-methoxy-N-methyl-
- CBNumber
- CB1151907
- Molecular Formula
- C9H10FNO2
- Formula Weight
- 183.18
- MOL File
- 226260-01-1.mol
3-FLUORO-N-METHOXY-N-METHYLBENZAMIDE Property
- Boiling point:
- 300.5±25.0 °C(Predicted)
- Density
- 1.179±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
Safety
- HS Code
- 2924297099
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 1381AB
- Product name
- 3-Fluoro-N-methoxy-N-methylbenzamide
- Packaging
- 25g
- Price
- $181
- Updated
- 2021/12/16
- Product number
- HCH0021914
- Product name
- 3-FLUORO-N-METHOXY-N-METHYLBENZAMIDE
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $1239.43
- Updated
- 2021/12/16
- Product number
- CM251490
- Product name
- 3-Fluoro-N-methoxy-N-methylbenzamide
- Purity
- 95%
- Packaging
- 10g
- Price
- $234
- Updated
- 2021/12/16
- Product number
- 226260011
- Product name
- 3-Fluoro-N-methoxy-N-methylbenzamide
- Packaging
- 10g
- Price
- $257.5
- Updated
- 2021/12/16
- Product number
- CM251490
- Product name
- 3-Fluoro-N-methoxy-N-methylbenzamide
- Purity
- 95%
- Packaging
- 25g
- Price
- $468
- Updated
- 2021/12/16
3-FLUORO-N-METHOXY-N-METHYLBENZAMIDE Chemical Properties,Usage,Production
Synthesis
6638-79-5
1711-07-5
226260-01-1
Triethylamine (Et3N, 383 g, 3.78 mol) was added to a solution of N,O-dimethylhydroxylamine hydrochloride (138 g, 1.42 mol) in dichloromethane (DCM, 1.5 L) at room temperature (RT). 3-Fluorobenzoyl chloride (150 g, 946 mmol) was added dropwise to the stirred mixture at 0 °C and protected by nitrogen (N2). The reaction solution was stirred at the same temperature for 1 hour, followed by slow warming to room temperature and continued stirring for 10 hours. The reaction mixture was poured into water (~1 L) and extracted with ethyl acetate (EtOAc, 2 x 500 mL). The organic phases were combined, dried over anhydrous sodium sulfate (Na2SO4), filtered and concentrated. The residue was purified by fast column chromatography (eluent: petroleum ether, PE) to afford N-methyl-N-methoxy-3-fluorobenzamide (1-2) as a white solid (150 g, yield: 86.5%).1H NMR (400 MHz, CDCl3): δ 7.49-7.43 (1H, m), 7.41-7.32 (2H, m), 7.18 -7.10 (1H, m), 3.54 (3H, s), 3.34 (3H, s).
References
[1] Bioorganic and Medicinal Chemistry Letters, 2010, vol. 20, # 4, p. 1415 - 1419
[2] Patent: WO2016/145103, 2016, A1. Location in patent: Paragraph 0165
[3] Patent: US6174874, 2001, B1
[4] Patent: US2008/249095, 2008, A1. Location in patent: Page/Page column 44
3-FLUORO-N-METHOXY-N-METHYLBENZAMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
3-FLUORO-N-METHOXY-N-METHYLBENZAMIDE Suppliers
- Tel
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- Fax
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- enquiry@leancare.co.uk
- Country
- United Kingdom
- ProdList
- 6446
- Advantage
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View Lastest Price from 3-FLUORO-N-METHOXY-N-METHYLBENZAMIDE manufacturers
- Product
- 3-FLUORO-N-METHOXY-N-METHYLBENZAMIDE 226260-01-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2020-01-08