1-Amino-4-methylpiperazine

Product Name: 1-Amino-4-methylpiperazine
CAS No.: 6928-85-4
Chemical Name: 1-Amino-4-methylpiperazine
Synonyms: AMPRZ;1A4MP;1-Amino-4-Methyl;TIMTEC-BB SBB004299;AMINOMETHYLPIPERAZINE;LABOTEST-BB LT00005082;1-piperazinylmethanamine;1-METHYL-4-AMINOPIERAZINE;1-AMINO-4-METHYLPIERAZINE;4-Methyl-1-piperazinamine
CBNumber: CB1177970
Molecular Formula: C5H13N3
Formula Weight: 115.18
MOL File: 6928-85-4.mol

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1-Amino-4-methylpiperazine Property

Boiling point:: 172-175 °C (lit.)
Density: 0.957 g/mL at 25 °C (lit.)
vapor pressure: 1.29hPa at 25℃
refractive index: 1.4835-1.4855
Flash point:: 62 °C
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: water: soluble
form: Viscous Solution
pka: 7?+-.0.42(Predicted)
color: Clear
Water Solubility: miscible
Sensitive: Air & Light Sensitive
BRN: 103334
InChI: 1S/C5H13N3/c1-7-2-4-8(6)5-3-7/h2-6H2,1H3
InChIKey: RJWLLQWLBMJCFD-UHFFFAOYSA-N
SMILES: CN1CCN(N)CC1
LogP: -1.61 at 25℃
CAS DataBase Reference: 6928-85-4(CAS DataBase Reference)
NIST Chemistry Reference: 1-Amino-4-methylpiperazine(6928-85-4)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-20/21/22
Safety Statements: 24/25-36-26
RIDADR: 2733
WGK Germany: 3
HazardClass: 3
PackingGroup: III
HS Code: 29335995
Storage Class: 10 - Combustible liquids
Hazard Classifications: Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 255688
Product name: 1-Amino-4-methylpiperazine
Purity: 97%
Packaging: 25g
Price: $63.27
Updated: 2025/07/31

TCI Chemical

Product number: A1192
Product name: 1-Amino-4-methylpiperazine
Purity: >98.0%(GC)(T)
Packaging: 25mL
Price: $77
Updated: 2025/07/31

TCI Chemical

Product number: A1192
Product name: 1-Amino-4-methylpiperazine
Purity: >98.0%(GC)(T)
Packaging: 500mL
Price: $1141
Updated: 2025/07/31

TRC

Product number: A613435
Product name: 1-Amino-4-methylpiperazine(>90%)
Packaging: 100g
Price: $110
Updated: 2021/12/16

Frontier Specialty Chemicals

Product number: JK200248
Product name: 1-Amino-4-methylpiperazine
Purity: 98%
Packaging: 5g
Price: $13
Updated: 2021/12/16

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1-Amino-4-methylpiperazine Chemical Properties,Usage,Production

Chemical Properties

clear colorless to light yellow liquid

Uses

1-Amino-4-methylpiperazine has been used:
in synthesis of pyrazolo-pyrazine, -pyridine derivatives and 2-[(4-methylpiperazin-1-yl)iminomethyl]phenol
as a solvating and stabilizing agent in the preparation of uniform Ag nanoparticles (<10nm)
synthesis of N-(4-Fluorobenzylidene)-4-methylpiperazin1-amine
synthesis of 4-Methyl-N-(3,4,5-trimethoxybenzylidene) piperazin-1-amine
synthesis of N-(3,4-Dichlorobenzylidene)-4- methylpiperazin-1-amine
synthesis of N-(4-(Diethylamino)benzylidene)-4- methylpiperazin-1-amine
synthesis of N-(2,5-Dimethoxybenzylidene)-4- methylpiperazin-1-amine
synthesis of 4-Methyl-N-((5-nitrofuran-2- yl)methylene)piperazin-1-amine

Application

1-Amino-4-methylpiperazine, a derivative of piperazine, is used widely as an intermediate in the synthesis of pharmaceutical agents. It is an important intermediate for Rifampicin. Rifampicin , known as rifampin, is an antibiotic used to treat a several kinds of bacterial infections such as tuberculosis, leprosy and Legionnare's disease.

Preparation

1-Amino-4-methylpiperazine is obtained from piperazine hexahydrate through the steps of methylation, hydrolysis, nitrosation and reduction.
1-Amino-4-methylpiperazine is synthesized by chlorination of methyl(diethanol)amine (I) and subsequent cyclization of the di(chloroethyl)amine (II) obtained in aqueous hydrazine.

Flammability and Explosibility

Not classified

1-Amino-4-methylpiperazine Preparation Products And Raw materials

Raw materials

ZINC PIPERAZINE HEXAHYDRATE 1-Methylpiperazine Water 1-Piperazinecarbaldehyde

Preparation Products

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1-Amino-4-methylpiperazine Suppliers

Americas 1 Belgium 1 Canada 1 China 262 Europe 3 France 2 Germany 6 India 12 Japan 5 Singapore 1 Slovakia 1 South Korea 1 Switzerland 1 The Netherlands 1 Ukraine 2 United Kingdom 12 United States 31 Global 343

Shanghai Qiao Chemical Science Co., Ltd

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View Lastest Price from 1-Amino-4-methylpiperazine manufacturers

HANGZHOU HAILAN CHEMICAL CO.,LTD.

Product: 1-Amino-4-methylpiperazine 6928-85-4
Price: US $1.90/drum
Min. Order: 1drum
Purity: 99
Supply Ability: 200tons
Release date: 2025-08-13

Henan Aochuang Chemical Co.,Ltd.

Product: 1-Amino-4-methylpiperazine 6928-85-4
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2022-09-29

Shaanxi Dideu New Materials Co. Ltd

Product: 1-Amino-4-methylpiperazine 6928-85-4
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-02-18

6928-85-4, 1-Amino-4-methylpiperazineRelated Search:

BUTYLAMINE HYDROCHLORIDE 1-AMINOHEPTADECANE 1-AMINONONADECANE Rifampicin 4-[(2-METHOXYETHYL)AMINO]-1-METHYLPIPERAZINE 1-AMINO-4-METHYLPIPERAZINE DIHYDROCHLORIDE MONOHYDRATE

LABOTEST-BB LT00005082

1-METHYL-4-AMINOPIERAZINE

1-METHYL-4-AMINOPIPERAZINE

1-AMINO-4-METHYLPIERAZINE

1-AMINO-4-METHYLPIPERAZINE

4-AMINO-1-METHYLPIPERAZINE

4-methylpiperazin-1-ylamine

AMPRZ

TIMTEC-BB SBB004299

N-METHYL-N-AMINOPIPERAZINE

1-Piperazinamine, 4-methyl-

1-AMino-4-Methylpiperazine, 99% 25GR

1-Amino-4-methylpiperazine 97%

Amino methyl piperazine Alias

4-Methyl-1-piperazinamine

4-methylpiperazin-1-amine

AMINOMETHYLPIPERAZINE

1-Amino-4-Methyl

1-Amino-4-methylpiperazine ,98%

1-Methylpiperazine-4-amine

4-Methyl-1-aminopiperazine

1-Amino-4-methylpiperazine,99%

1-METHYL-4-AMINOPIPERAZINE(1-AMINO-4-METHYLPIPERAZINE)

1-piperazinylmethanamine

1-Amino-4-methylpiperazine &gt

1-Amino-4-methylpiperazine ISO 9001：2015 REACH

1-Amino-4-methylpiperazine (>90%)

6928-85-4 1-Amino-4-methylpiperazine

1-Amino 4-Methyl Piperazine (AMP)

1A4MP

6928-85-4

6298-85-4

C5H13N3

C5H13N2

Piperazines

Heterocyclic Building Blocks

Building Blocks

Heterocyclic Building Blocks

Piperazines

Piperaizine

Piperazine derivates