(2-AMINO-5-BROMOPHENYL)METHANOL
Uses- Product Name
- (2-AMINO-5-BROMOPHENYL)METHANOL
- CAS No.
- 20712-12-3
- Chemical Name
- (2-AMINO-5-BROMOPHENYL)METHANOL
- Synonyms
- Ambroxol Impurity 50;2-Amino-5-bromobenzyl alcohol;(2-Amino-5-Bromophenyl)methonal;2-Amino-5-bromo-benzenemethanol;(2-AMINO-5-BROMOPHENYL)METHANOL;Benzenemethanol, 2-amino-5-bromo-;(2-AMINO-5-BROMOPHENYL)METHANOL（WS200466）
- CBNumber
- CB1179510
- Molecular Formula
- C7H8BrNO
- Formula Weight
- 202.05
- MOL File
- 20712-12-3.mol
(2-AMINO-5-BROMOPHENYL)METHANOL Property
- Melting point:
- 112 - 114°C
- Boiling point:
- 329.6±27.0 °C(Predicted)
- Density
- 1.660±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 14.13±0.10(Predicted)
- color
- Off-White to Pale Red
Safety
- RIDADR
- UN2811
- HS Code
- 2922190090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A602138
- Product name
- (2-Amino-5-bromophenyl)methanol
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- CS-W005467
- Product name
- (2-Amino-5-bromophenyl)methanol
- Purity
- 99.57%
- Packaging
- 1g
- Price
- $28
- Updated
- 2021/12/16
- Product number
- FA142908
- Product name
- (2-Amino-5-bromophenyl)methanol
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- 4656-9-08
- Product name
- (2-Amino-5-bromophenyl)methanol
- Packaging
- 1g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- CS-W005467
- Product name
- (2-Amino-5-bromophenyl)methanol
- Purity
- 99.57%
- Packaging
- 5g
- Price
- $80
- Updated
- 2021/12/16
(2-AMINO-5-BROMOPHENYL)METHANOL Chemical Properties,Usage,Production
Uses
2-Amino-5-bromobenzyl alcohol is an alcohol derivative that can be used as an organic reagent in organic synthesis and other chemical processes.
Synthesis
5794-88-7
20712-12-3
General procedure for the synthesis of 2-amino-5-bromobenzenemethanol from 2-amino-5-bromobenzoic acid: 2-amino-5-bromobenzoic acid (10 g, 46.3 mmol) was added to a 500 mL reaction vial, dissolved in anhydrous tetrahydrofuran (THF) (100 mL), and the reaction was carried out under nitrogen protection. Borane tetrahydrofuran solution (1 M, 231 mL, 231 mmol) was added slowly and dropwise under ice bath cooling conditions. After the dropwise addition, the reaction mixture was gradually warmed to room temperature and stirred overnight. Upon completion of the reaction, water (150 mL) was added slowly under cooling in an ice bath to quench the reaction. The resulting mixture was extracted with ethyl acetate, the organic layer was washed sequentially with water and sodium hydride solution, and then dried with anhydrous sodium sulfate. Finally, the solvent was removed by evaporation under reduced pressure to afford the target product 2-amino-5-bromobenzenemethanol (9.7 g, 100% yield) as a white solid.
References
[1] ACS Catalysis, 2013, vol. 3, # 4, p. 622 - 624
[2] Chemical Communications, 2017, vol. 53, # 1, p. 216 - 219
[3] Organic Letters, 2017, vol. 19, # 12, p. 3219 - 3222
[4] Patent: CN107304201, 2017, A. Location in patent: Paragraph 0061; 0064
[5] Tetrahedron Letters, 2017, vol. 58, # 40, p. 3795 - 3799
(2-AMINO-5-BROMOPHENYL)METHANOL Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from (2-AMINO-5-BROMOPHENYL)METHANOL manufacturers
- Product
- (2-AMINO-5-BROMOPHENYL)METHANOL 20712-12-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2019-07-12