5-METHYLINDOLE-3-CARBOXYLIC ACID METHYL ESTER
- Product Name
- 5-METHYLINDOLE-3-CARBOXYLIC ACID METHYL ESTER
- CAS No.
- 227960-12-5
- Chemical Name
- 5-METHYLINDOLE-3-CARBOXYLIC ACID METHYL ESTER
- Synonyms
- RARECHEM AL BF 0707;Methyl 5-methylindole-3-carboxylate;METHYL 5-METHYL-1H-INDOLE-3-CARBOXYLATE;5-METHYLINDOLE-3-CARBOXYLIC ACID METHYL ESTER;5-Methylindole-3-Carbocylic acid methyl ester;1H-Indole-3-carboxylicacid,5-Methyl-,Methylester;5-METHYL-1H-INDOLE-3-CARBOXYLIC ACID METHYL ESTER
- CBNumber
- CB1196308
- Molecular Formula
- C11H11NO2
- Formula Weight
- 189.21
- MOL File
- 227960-12-5.mol
5-METHYLINDOLE-3-CARBOXYLIC ACID METHYL ESTER Property
- Boiling point:
- 345.1±22.0 °C(Predicted)
- Density
- 1.212±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 15.59±0.30(Predicted)
- Appearance
- Off-white to light yellow Solid
- CAS DataBase Reference
- 227960-12-5(CAS DataBase Reference)
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M313740
- Product name
- 5-Methylindole-3-carboxylicacidmethylester
- Packaging
- 100mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- OR912748
- Product name
- 5-Methylindole-3-carboxylicacidmethylester
- Purity
- 95%
- Packaging
- 1g
- Price
- $170
- Updated
- 2021/12/16
- Product number
- Z3602
- Product name
- 5-Methylindole-3-carboxylicacidmethylester
- Packaging
- 5g
- Price
- $632
- Updated
- 2021/12/16
- Product number
- CHM0027377
- Product name
- 5-METHYLINDOLE-3-CARBOXYLIC ACID METHYL ESTER
- Purity
- 95.00%
- Packaging
- 250MG
- Price
- $642.76
- Updated
- 2021/12/16
- Product number
- OR912748
- Product name
- 5-Methylindole-3-carboxylicacidmethylester
- Purity
- 95%
- Packaging
- 5g
- Price
- $665
- Updated
- 2021/12/16
5-METHYLINDOLE-3-CARBOXYLIC ACID METHYL ESTER Chemical Properties,Usage,Production
Synthesis
67-56-1
10242-02-1
227960-12-5
GENERAL PROCEDURE: Following the above procedure, the crude reaction mixture was diluted with methanol (MeOH) and cooled to 0 °C. Sulfoxide chloride (SOCl2, 36 μL, 0.5 mmol) was then slowly added and the reaction was stirred at room temperature for 3 hours. Upon completion of the reaction, additional methanol (MeOH) was added and the reaction mixture was heated to reflux for 6 hours. At the end of the reaction, the reaction was quenched with deionized water (H2O) and extracted with ethyl acetate (EtOAc, 3 times). All organic layers were combined and dried with anhydrous magnesium sulfate (MgSO4) and subsequently concentrated under reduced pressure. Finally, the crude product was purified by preparative thin layer chromatography (TLC, unfolding reagent ratio petroleum ether: ethyl acetate = 7:3) to afford the target compounds, methyl 5-methylindole-3-carboxylate (5a-b).
References
[1] Heterocycles, 2015, vol. 90, # 2, p. 1196 - 1204
5-METHYLINDOLE-3-CARBOXYLIC ACID METHYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
5-METHYLINDOLE-3-CARBOXYLIC ACID METHYL ESTER Suppliers
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View Lastest Price from 5-METHYLINDOLE-3-CARBOXYLIC ACID METHYL ESTER manufacturers
- Product
- 5-METHYLINDOLE-3-CARBOXYLIC ACID METHYL ESTER 227960-12-5
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10 m
- Release date
- 2024-11-29
- Product
- 5-METHYLINDOLE-3-CARBOXYLIC ACID METHYL ESTER 227960-12-5
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11
- Product
- 5-METHYLINDOLE-3-CARBOXYLIC ACID METHYL ESTER 227960-12-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2020-01-08