4-Phenylthiazole-2-carboxylic acid
- Product Name
- 4-Phenylthiazole-2-carboxylic acid
- CAS No.
- 59020-44-9
- Chemical Name
- 4-Phenylthiazole-2-carboxylic acid
- Synonyms
- CHEMBRDG-BB 4401055;4-phenyl-2-thiazolecarboxylic acid;4-PHENYL-THIAZOLE-2-CARBOXYLIC ACID;2-Thiazolecarboxylic acid,4-phenyl-;4-PHENYL-1,3-THIAZOLE-2-CARBOXYLIC ACID;JR-14104, 4-Phenylthiazole-2-carboxylic acid, 97%;4-phenyl-1,3-thiazole-2-carboxylic acid(SALTDATA: FREE)
- CBNumber
- CB1197471
- Molecular Formula
- C10H7NO2S
- Formula Weight
- 205.23
- MOL File
- 59020-44-9.mol
4-Phenylthiazole-2-carboxylic acid Property
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- form
- crystalline powder
- color
- White
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- CDS006900
- Product name
- 4-Phenyl-1,3-thiazole-2-carboxylic acid
- Purity
- Aldrich<SUP>CPR</SUP>
- Packaging
- 25 mg
- Price
- $73.1
- Updated
- 2025/07/31
- Product number
- P322683
- Product name
- 4-phenylthiazole-2-carboxylicAcid
- Packaging
- 250mg
- Price
- $130
- Updated
- 2021/12/16
- Product number
- P322683
- Product name
- 4-phenylthiazole-2-carboxylicAcid
- Packaging
- 25mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- P322683
- Product name
- 4-phenylthiazole-2-carboxylicAcid
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 063472
- Product name
- 4-Phenyl-1,3-thiazole-2-carboxylic acid
- Packaging
- 500mg
- Price
- $324
- Updated
- 2021/12/16
4-Phenylthiazole-2-carboxylic acid Chemical Properties,Usage,Production
Synthesis
31877-30-2
59020-44-9
GENERAL METHOD: To a methanolic solution of ethyl 4-phenylthiazole-2-carboxylate (1 equiv.) was slowly added 2N sodium hydroxide solution at room temperature. The reaction mixture was stirred continuously for 4 h. After completion of the reaction, the methanol solvent was removed by rotary evaporator. The residue was adjusted to pH 5-6 with 1N hydrochloric acid solution, at which point the target product 4-phenylthiazole-2-carboxylic acid precipitated as a white solid. The precipitate was collected by filtration and washed with appropriate amount of deionized water and finally dried in a vacuum drying oven to give pure 4-phenylthiazole-2-carboxylic acid (1a-i).
References
[1] European Journal of Medicinal Chemistry, 2017, vol. 137, p. 96 - 107
[2] Patent: US2018/271846, 2018, A1. Location in patent: Paragraph 0150; 0153; 0154
[3] Patent: US2010/144805, 2010, A1. Location in patent: Page/Page column 45; 46
[4] Patent: US2007/123504, 2007, A1. Location in patent: Page/Page column 24
[5] Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981, p. 2335 - 2339
4-Phenylthiazole-2-carboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-Phenylthiazole-2-carboxylic acid manufacturers
- Product
- 4-Phenylthiazole-2-carboxylic acid 59020-44-9
- Price
- US $6.60/KG
- Min. Order
- 1KG
- Purity
- 97%-99%
- Supply Ability
- 1kg -1000kg
- Release date
- 2020-01-02