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4-Phenylthiazole-2-carboxylic acid

Product Name
4-Phenylthiazole-2-carboxylic acid
CAS No.
59020-44-9
Chemical Name
4-Phenylthiazole-2-carboxylic acid
Synonyms
CHEMBRDG-BB 4401055;4-phenyl-2-thiazolecarboxylic acid;4-PHENYL-THIAZOLE-2-CARBOXYLIC ACID;2-Thiazolecarboxylic acid,4-phenyl-;4-PHENYL-1,3-THIAZOLE-2-CARBOXYLIC ACID;JR-14104, 4-Phenylthiazole-2-carboxylic acid, 97%;4-phenyl-1,3-thiazole-2-carboxylic acid(SALTDATA: FREE)
CBNumber
CB1197471
Molecular Formula
C10H7NO2S
Formula Weight
205.23
MOL File
59020-44-9.mol
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4-Phenylthiazole-2-carboxylic acid Property

storage temp. 
Sealed in dry,Store in freezer, under -20°C
form 
crystalline powder
color 
White
InChI
1S/C10H7NO2S/c12-10(13)9-11-8(6-14-9)7-4-2-1-3-5-7/h1-6H,(H,12,13)
InChIKey
ORSGNNVYFOPYKB-UHFFFAOYSA-N
SMILES
OC(=O)c1nc(cs1)-c2ccccc2
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Safety

Hazard Codes 
Xn
Risk Statements 
22
WGK Germany 
WGK 3
HazardClass 
IRRITANT
HS Code 
2934100090
Storage Class
11 - Combustible Solids
Hazard Classifications
Acute Tox. 4 Oral
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
CDS006900
Product name
4-Phenyl-1,3-thiazole-2-carboxylic acid
Purity
Aldrich<SUP>CPR</SUP>
Packaging
25 mg
Price
$77.9
Updated
2026/03/19
TRC
Product number
P322683
Product name
4-phenylthiazole-2-carboxylicAcid
Packaging
250mg
Price
$130
Updated
2021/12/16
TRC
Product number
P322683
Product name
4-phenylthiazole-2-carboxylicAcid
Packaging
25mg
Price
$45
Updated
2021/12/16
TRC
Product number
P322683
Product name
4-phenylthiazole-2-carboxylicAcid
Packaging
50mg
Price
$60
Updated
2021/12/16
Matrix Scientific
Product number
063472
Product name
4-Phenyl-1,3-thiazole-2-carboxylic acid
Packaging
500mg
Price
$324
Updated
2021/12/16
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4-Phenylthiazole-2-carboxylic acid Chemical Properties,Usage,Production

Synthesis

31877-30-2

59020-44-9

GENERAL METHOD: To a methanolic solution of ethyl 4-phenylthiazole-2-carboxylate (1 equiv.) was slowly added 2N sodium hydroxide solution at room temperature. The reaction mixture was stirred continuously for 4 h. After completion of the reaction, the methanol solvent was removed by rotary evaporator. The residue was adjusted to pH 5-6 with 1N hydrochloric acid solution, at which point the target product 4-phenylthiazole-2-carboxylic acid precipitated as a white solid. The precipitate was collected by filtration and washed with appropriate amount of deionized water and finally dried in a vacuum drying oven to give pure 4-phenylthiazole-2-carboxylic acid (1a-i).

References

[1] European Journal of Medicinal Chemistry, 2017, vol. 137, p. 96 - 107
[2] Patent: US2018/271846, 2018, A1. Location in patent: Paragraph 0150; 0153; 0154
[3] Patent: US2010/144805, 2010, A1. Location in patent: Page/Page column 45; 46
[4] Patent: US2007/123504, 2007, A1. Location in patent: Page/Page column 24
[5] Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981, p. 2335 - 2339

4-Phenylthiazole-2-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Phenylthiazole-2-carboxylic acid Suppliers

J & K SCIENTIFIC LTD.
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View Lastest Price from 4-Phenylthiazole-2-carboxylic acid manufacturers

Career Henan Chemical Co
Product
4-Phenylthiazole-2-carboxylic acid 59020-44-9
Price
US $6.60/KG
Min. Order
1KG
Purity
97%-99%
Supply Ability
1kg -1000kg
Release date
2020-01-02