FMOC-HYDRAZIDE HCL
- Product Name
- FMOC-HYDRAZIDE HCL
- CAS No.
- 35661-51-9
- Chemical Name
- FMOC-HYDRAZIDE HCL
- Synonyms
- FMOC-NHNH2;(9H-fluoren-9-yl)Methyl hydrazinecarboxylate;9-Fluorenylmethyl carbazate;N-(9-Fluorenylmethoxycarbonyl) hydrazine (FMOC hydrazine);FMOC-NHNH2 HCL;FMOC-HYDRAZIDE HCL;9-FluorenylmethylCarbazate>9-Fluorenylmethyl carbazate, >=99%;Carbazic Acid 9-Fluorenylmethyl Ester;9H-fluoren-9-ylmethyl N-aminocarbamate
- CBNumber
- CB1210174
- Molecular Formula
- C15H14N2O2
- Formula Weight
- 254.28
- MOL File
- 35661-51-9.mol
FMOC-HYDRAZIDE HCL Property
- Melting point:
- ~170 °C (dec.)
- Boiling point:
- 485.8±14.0 °C(Predicted)
- Density
- 1.259±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,2-8°C
- form
- powder to crystal
- pka
- 10.21±0.20(Predicted)
- color
- White to Almost white
- BRN
- 2470262
- InChI
- InChI=1S/C15H14N2O2/c16-17-15(18)19-9-14-12-7-3-1-5-10(12)11-6-2-4-8-13(11)14/h1-8,14H,9,16H2,(H,17,18)
- InChIKey
- YGCGPEUVGHDMLO-UHFFFAOYSA-N
- SMILES
- N(C(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O)N
- CAS DataBase Reference
- 35661-51-9
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38-38-37-36
- Safety Statements
- 26-36
- WGK Germany
- 3
- F
- 3-10
- HS Code
- 29280000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 46917
- Product name
- 9-Fluorenylmethyl carbazate
- Purity
- for HPLC derivatization, LiChropur?, ≥99.0%
- Packaging
- 250MG
- Price
- $101
- Updated
- 2022/05/15
- Product number
- F0872
- Product name
- 9-Fluorenylmethyl Carbazate
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 5g
- Price
- $55
- Updated
- 2025/07/31
- Product number
- F0872
- Product name
- 9-Fluorenylmethyl Carbazate
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 25g
- Price
- $144
- Updated
- 2025/07/31
- Product number
- F632050
- Product name
- 9-Fluorenylmethyl Carbazate
- Packaging
- 500mg
- Price
- $95
- Updated
- 2021/12/16
- Product number
- B437
- Product name
- 9-Fluorenylmethyl Carbazate
- Packaging
- 1g
- Price
- $14
- Updated
- 2021/12/16
FMOC-HYDRAZIDE HCL Chemical Properties,Usage,Production
Chemical Properties
white powder
Uses
9-Fluorenylmethyl Carbazate is a reagent for the sensitive fluorogenic derivatization of carbohydrates.
Synthesis
28920-43-6
35661-51-9
General procedure for the synthesis of 9-fluorenylmethylhydrazinyl formate from 9-fluorenylmethylhydrazinyl formate as chloroformic acid methyl ester (FmocCl): to a well-stirred solution of hydrazine hydrate (19 g, 386 mmol) dissolved in 150 mL of CH3CN/H2O (1:1, v/v) at 0 °C, FmocCl (10 g, 38.65 mmol) dissolved in a solution of 600 mL of CH3CN. The reaction mixture was then warmed to room temperature and stirring was continued for 12 hours. Upon completion of the reaction, the mixture was concentrated in vacuum to about 150 mL and filtered to give the white solid product 9-fluorenylmethylhydrazinyl formate. The product was washed sequentially with water and hexane, dried to constant weight, and finally obtained under vacuum as 9.74 g (99% yield) of a pure product with a melting point of 172-173 °C. The structure of the product was confirmed by 1H NMR and 13C NMR: 1H NMR (DMSO) δ 4.08 (brs, 2H), 4.21 (t, J = 7.2 Hz, 1H), 4.28 (d, J = 7.2 Hz, 2H), 7.32 (t, J = 7.4 Hz, 2H), 7.42 (t, J = 7.4 Hz, 2H), 7.69 ( d, J = 7.4 Hz, 2H), 7.89 (d, J = 7.4 Hz, 2H), 8.36 (brs, 1H); 13C NMR (DMSO) δ 47.7, 66.7, 121.1 (2C), 126.3 (2C), 128.1 (2C), 128.7 (2C), 141.7 (2C), 144.9 (2C), 159.2. 159.2.
References
[1] Journal of Organic Chemistry, 2012, vol. 77, # 12, p. 5271 - 5278
[2] Patent: US9115171, 2015, B2. Location in patent: Page/Page column 43
[3] Patent: EP2182974, 2015, B1. Location in patent: Paragraph 0093
[4] Patent: CN108178739, 2018, A. Location in patent: Paragraph 0032; 0033; 0034
[5] Tetrahedron, 2011, vol. 67, # 42, p. 8187 - 8194
FMOC-HYDRAZIDE HCL Preparation Products And Raw materials
Raw materials
Preparation Products
FMOC-HYDRAZIDE HCL Suppliers
- Tel
- 800-4238616
- Fax
- +1-888-520-1075 / +1-503-283-1987
- sales@tciamerica.com
- Country
- Americas
- ProdList
- 23653
- Advantage
- 75
View Lastest Price from FMOC-HYDRAZIDE HCL manufacturers
- Product
- FMOC-HYDRAZIDE HCL 35661-51-9
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1ton
- Release date
- 2022-09-26
- Product
- FMOC-HYDRAZIDE HCL 35661-51-9
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- FMOC-HYDRAZIDE HCL 35661-51-9
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-08