ChemicalBook > CAS DataBase List > 2-(Trifluoromethyl)benzenesulfonamide

2-(Trifluoromethyl)benzenesulfonamide

Product Name
2-(Trifluoromethyl)benzenesulfonamide
CAS No.
1869-24-5
Chemical Name
2-(Trifluoromethyl)benzenesulfonamide
Synonyms
BUTTPARK 91\08-54;Tritosulfuron Metabolite BH635-2;2-(Trifluoromethyl)benzenesulfomide;2-(TRIFLUOROMETHYL)BENZENESULFONAMIDE;2-(TRIFLUOROMETHYL)BENZENESULPHONAMIDE;BenzenesulfonaMide, 2-(trifluoroMethyl)-;(2-Trifluoromethylphenyl)-methanesulfonamide;2-(Trifluoromethyl)benzenesulfonamide ISO 9001：2015 REACH
CBNumber
CB1211601
Molecular Formula
C7H6F3NO2S
Formula Weight
225.19
MOL File
1869-24-5.mol
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2-(Trifluoromethyl)benzenesulfonamide Property

Melting point:
180-184 °C(lit.)
Boiling point:
320.5±52.0 °C(Predicted)
Density 
1.482±0.06 g/cm3(Predicted)
Flash point:
>230 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
soluble in Methanol
form 
powder to crystal
pka
9.55±0.60(Predicted)
color 
White to Almost white
BRN 
2697078
CAS DataBase Reference
1869-24-5(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
22
Safety Statements 
22-24/25-36
RIDADR 
2811
WGK Germany 
3
HazardClass 
IRRITANT
PackingGroup 
I
HS Code 
29350090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H301Toxic if swalloed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P321Specific treatment (see … on this label).

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
563552
Product name
2-(Trifluoromethyl)benzenesulfonamide
Purity
97%
Packaging
1g
Price
$41.8
Updated
2023/06/20
TCI Chemical
Product number
T3368
Product name
2-(Trifluoromethyl)benzenesulfonamide
Purity
>98.0%(HPLC)(N)
Packaging
5g
Price
$52
Updated
2025/07/31
TCI Chemical
Product number
T3368
Product name
2-(Trifluoromethyl)benzenesulfonamide
Purity
>98.0%(HPLC)(N)
Packaging
25g
Price
$160
Updated
2025/07/31
TRC
Product number
T797153
Product name
2-(Trifluoromethyl)benzenesulfonamide
Packaging
50mg
Price
$60
Updated
2021/12/16
Matrix Scientific
Product number
024671
Product name
2-(Trifluoromethyl)benzenesulfonamide
Purity
97%
Packaging
1g
Price
$10
Updated
2021/12/16
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2-(Trifluoromethyl)benzenesulfonamide Chemical Properties,Usage,Production

Chemical Properties

Pale yellow to off-white crystalline powder

Synthesis

776-04-5

1869-24-5

General procedure for the synthesis of o-(trifluoromethyl)benzenesulfonamide from 2-(trifluoromethyl)benzenesulfonyl chloride: Intermediate 1: Preparation of 2-(trifluoromethyl)benzenesulfonamide (see Scheme 3, compound XXI) To a solution of 2-(trifluoromethyl)benzenesulfonyl chloride (5 g, 20.44 mmol, 1.00 eq.) in anhydrous THF (5.00 mL) was slowly added an ethanol solution of 2 M ammonia (71 mL) under nitrogen protection and at room temperature. The reaction mixture was stirred at room temperature for 20 hours. After completion of the reaction, the solvent was removed by evaporation and the residue was redissolved in EtOAc (150 mL) and washed sequentially with saturated aqueous NH4Cl solution (50 mL) and brine (50 mL). The organic layer was dried over anhydrous MgSO4, filtered and the solvent concentrated to give pure 2-(trifluoromethyl)benzenesulfonamide as a pale yellow solid (4.6 g, 89% yield, 98.6% HPLC purity). The compound was used directly in the next reaction without further purification. 1H NMR (300MHz, CDCl3) δ: 5.0 (m, 2H), 7.6 (m, 2H), 7.8 (m, 1H), 8.3 (m, 1H). MS (ESI): m/z 224.1 [M-H]-.

References

[1] Patent: US6610853, 2003, B1
[2] Patent: WO2006/111560, 2006, A2. Location in patent: Page/Page column 48
[3] Bioorganic and Medicinal Chemistry Letters, 2014, vol. 24, # 9, p. 2222 - 2225

2-(Trifluoromethyl)benzenesulfonamide Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-(Trifluoromethyl)benzenesulfonamide manufacturers

Henan Fengda Chemical Co., Ltd
Product
2-(Trifluoromethyl)benzenesulfonamide 1869-24-5
Price
US $100.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-24
Hebei Zhanyao Biotechnology Co. Ltd
Product
2-(Trifluoromethyl)benzenesulfonamide 1869-24-5
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 tons
Release date
2021-10-19
Zhuozhou Wenxi import and Export Co., Ltd
Product
2-(Trifluoromethyl)benzenesulfonamide 1869-24-5
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11

1869-24-5, 2-(Trifluoromethyl)benzenesulfonamideRelated Search:

Sulfanilamide 2-(Trifluoromethyl)benzoic acid Methanesulfonamide 3-(Trifluoromethyl)benzaldehyde 2-Methylbenzotrifluoride 2-Carbomethoxybenzenesulfonamide 2-(Trifluoromethyl)benzaldehyde Benzenesulfonamide 4-(Trifluoromethyl)benzene-1-sulfonyl chloride 2-Methylbenzaldehyde o-Toluic acid 2-(TRIFLUOROMETHOXY)BENZENESULFONAMIDE alpha,alpha,alpha-Trifluoro-o-cresol 2-TRIFLUOROMETHOXY TOLUENE 2-(Trifluoromethyl)benzenesulfonyl chloride 2'-(TRIFLUOROMETHOXY)ACETOPHENONE 2-(Trifluoromethoxy)benzoic acid HYDROFLUMETHIAZIDE

  • 2-(TRIFLUOROMETHYL)BENZENESULFONAMIDE
  • 2-(TRIFLUOROMETHYL)BENZENESULPHONAMIDE
  • (2-Trifluoromethylphenyl)-methanesulfonamide
  • BUTTPARK 91\08-54
  • BenzenesulfonaMide, 2-(trifluoroMethyl)-
  • 2-(Trifluoromethyl)benzenesulfomide
  • 2-(Trifluoromethyl)benzenesulfonamide ISO 9001：2015 REACH
  • Tritosulfuron Metabolite BH635-2
  • 1869-24-5
  • C6H4CF3SO2NH2
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  • Sulfur Compounds
  • Sulfonamides/Sulfinamides
  • Organic Building Blocks
  • API intermediates
  • Organic Building Blocks
  • Sulfonamides/Sulfinamides
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