BOC-GLY-OSU
- Product Name
- BOC-GLY-OSU
- CAS No.
- 3392-07-2
- Chemical Name
- BOC-GLY-OSU
- Synonyms
- BOC-GLY-OSU;Boc-L-Gly-OSu;BOC-GLYCINE-OSU;BOC-GLY-OSU USP/EP/BP;BOC-GLY-OSU;BOC-GLY-OSU;Boc-Gly-OSu >=99.0% (T);N-Boc-glycine N-succinimidyl ester;BOC-GLYCINE-HYDROXYSUCCINIMIDESTER;BOC-GLYCINE HYDROXYSUCCINIMIDE ESTER;Boc glycine-N-hydroxysccinimide ester
- CBNumber
- CB1233050
- Molecular Formula
- C11H16N2O6
- Formula Weight
- 272.25
- MOL File
- 3392-07-2.mol
BOC-GLY-OSU Property
- Melting point:
- 165-167 °C
- Density
- 1.31±0.1 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- pka
- 10.51±0.46(Predicted)
- form
- Powder
- color
- White
- Sensitive
- Hygroscopic
- BRN
- 1549242
- CAS DataBase Reference
- 3392-07-2(CAS DataBase Reference)
N-Bromosuccinimide Price
- Product number
- 15423
- Product name
- Boc-Gly-OSu
- Purity
- ≥99.0% (T)
- Packaging
- 5g
- Price
- $148
- Updated
- 2025/07/31
- Product number
- 15423
- Product name
- Boc-Gly-OSu
- Purity
- ≥99.0% (T)
- Packaging
- 25g
- Price
- $537
- Updated
- 2025/07/31
- Product number
- B656123
- Product name
- Boc-Gly-OSu
- Packaging
- 2.5g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 03793
- Product name
- Boc-glycine -hydroxysuccinimide ester
- Purity
- ≥ 99% (HPLC)
- Packaging
- 5G
- Price
- $30
- Updated
- 2021/12/16
- Product number
- AS112706
- Product name
- Boc-Gly-OSu
- Purity
- 97%
- Packaging
- 5G
- Price
- $49
- Updated
- 2021/12/16
BOC-GLY-OSU Chemical Properties,Usage,Production
Chemical Properties
White to off-white powder
Uses
peptide synthesis
reaction suitability
reaction type: Boc solid-phase peptide synthesis
Synthesis
4530-20-5
6066-82-6
3392-07-2
Step 2: Synthesis of 2,5-dioxopyrrolidin-1-yl 2-(tert-butoxycarbonylamino) acetate. N-Boc-glycine (7.31 g, 41.7 mmol) was dissolved in 100 mL of dichloromethane (DCM) and the solution was cooled to 15 °C. Subsequently, N-hydroxysuccinimide (5.28 g, 45.9 mmol) was added to the cooled solution. Under vigorous stirring, N,N'-dicyclohexylcarbodiimide (9.47 g, 45.9 mmol) was added to the formed suspension. The reaction mixture transformed into a cloudy white suspension within seconds. The reaction mixture was gradually warmed to room temperature and stirring was continued for 1 hour. Upon completion of the reaction, the insoluble by-products were removed by filtration through diatomaceous earth, the filtrate was washed with 50 mL of saturated sodium bicarbonate solution, dried over anhydrous sodium sulfate, and finally concentrated under vacuum to give the product as a white crystalline powder. Yield: 7.02 g, yield 61.8%. The product was characterized by 1H NMR (400 MHz, DMSO-d6): δ 1.38 (s, 9H), 2.80 (s, 4H), 4.07 (d, J = 6 Hz, 2H), 7.43 (br s, 1H). Mass spectrum (ESI) m/z 567.2 [2M + Na]+.
References
[1] Chemistry - A European Journal, 2016, vol. 22, # 52, p. 18865 - 18872
[2] Journal of the Chemical Society - Perkin Transactions 1, 1998, # 15, p. 2443 - 2449
[3] Chemical communications (Cambridge, England), 2003, # 23, p. 2870 - 2871
[4] ACS Medicinal Chemistry Letters, 2013, vol. 4, # 4, p. 402 - 407
[5] Helvetica Chimica Acta, 2004, vol. 87, # 5, p. 1077 - 1089
BOC-GLY-OSU Preparation Products And Raw materials
Raw materials
Preparation Products
BOC-GLY-OSU Suppliers
- Tel
- --
- Fax
- --
- tech@kokusan-chem.co.jp
- Country
- Japan
- ProdList
- 1658
- Advantage
- 51
View Lastest Price from BOC-GLY-OSU manufacturers
- Product
- Boc-Gly-OSu 3392-07-2
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 95%
- Supply Ability
- 1T+
- Release date
- 2024-02-28
- Product
- BOC-GLY-OSU 3392-07-2
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11
- Product
- Boc-Gly-OSu 3392-07-2
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2019-07-21