1-METHYL-5-NITRO-1H-INDAZOLE
- Product Name
- 1-METHYL-5-NITRO-1H-INDAZOLE
- CAS No.
- 5228-49-9
- Chemical Name
- 1-METHYL-5-NITRO-1H-INDAZOLE
- Synonyms
- SW-35;SWF-35;1-METHYL-5-NITROINDAZOLE;1-METHYL-5-NITRO-1H-INDAZOLE;5-Nitro-1-methyl-1H-indazole;1H-Indazole, 1-methyl-5-nitro-;1-METHYL-5-NITRO-1H-INDAZOLE, 98+%;1-methyl-5-nitro-1H-indazole, 1-methyl-5-nitroindazole, 1-methyl-5-nitro-1H-indazole, 1-Methyl-5-nitro-1H-indazol, 1-methyl-5-nitro-indazole, 1-Methyl-5-nitro-indazol, 1-Methyl-5-nitroindazol
- CBNumber
- CB1239421
- Molecular Formula
- C8H7N3O2
- Formula Weight
- 177.16
- MOL File
- 5228-49-9.mol
1-METHYL-5-NITRO-1H-INDAZOLE Property
- Melting point:
- 161-162°C
- Boiling point:
- 332.9±15.0 °C(Predicted)
- Density
- 1.42±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- form
- solid
- pka
- -0.82±0.30(Predicted)
- color
- yellow
- BRN
- 168080
- CAS DataBase Reference
- 5228-49-9(CAS DataBase Reference)
N-Bromosuccinimide Price
- Product number
- M218795
- Product name
- 1-Methyl-5-nitro-1H-indazole
- Packaging
- 500mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- W6706
- Product name
- 1-Methyl-5-nitro-1H-indazole
- Packaging
- 5g
- Price
- $161
- Updated
- 2021/12/16
- Product number
- OR14146
- Product name
- 1-Methyl-5-nitro-1H-indazole
- Packaging
- 250mg
- Price
- $15
- Updated
- 2021/12/16
- Product number
- 4H54-1-V8
- Product name
- 1-Methyl-5-nitro-1H-indazole
- Packaging
- 250mg
- Price
- $16
- Updated
- 2021/12/16
- Product number
- OR14146
- Product name
- 1-Methyl-5-nitro-1H-indazole
- Packaging
- 1g
- Price
- $28
- Updated
- 2021/12/16
1-METHYL-5-NITRO-1H-INDAZOLE Chemical Properties,Usage,Production
Synthesis
5401-94-5
74-88-4
5228-48-8
5228-49-9
GENERAL METHOD: Cesium carbonate (12.26 mmol) was added to a solution of 5-nitroindazole (6.13 mmol) in tetrahydrofuran (THF; 25 mL) at 0 °C. The reaction mixture was stirred at 0 °C for 15 min before iodomethane or allyl bromide (6.13 mmol) was added dropwise. The progress of the reaction was monitored by thin layer chromatography (TLC) until the starting material completely disappeared. After completion of the reaction, the mixture was concentrated. The crude product was dissolved in ethyl acetate (EtOAc; 50 mL), washed sequentially with water and brine, and the organic phase was dried over anhydrous magnesium sulfate (MgSO?). The solvent was removed by evaporation under reduced pressure, and the resulting residue was purified by silica gel column chromatography with ethyl acetate/hexane (3:7, v/v) as eluent to afford 1-alkyl-5-nitroindazole and 2-alkyl-5-nitroindazole, respectively.
References
[1] Synthetic Communications, 2015, vol. 45, # 17, p. 2005 - 2013
[2] Tetrahedron, 2008, vol. 64, # 28, p. 6711 - 6723
[3] Patent: US2014/371219, 2014, A1. Location in patent: Paragraph 0659; 0660; 0661
[4] Patent: WO2016/57834, 2016, A1. Location in patent: Paragraph 000406
1-METHYL-5-NITRO-1H-INDAZOLE Preparation Products And Raw materials
Raw materials
Preparation Products
1-METHYL-5-NITRO-1H-INDAZOLE Suppliers
- Tel
- --
- Fax
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- info@specs.net
- Country
- The Netherlands
- ProdList
- 6833
- Advantage
- 70
- Tel
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- Fax
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- brunschwig@brunschwig.nl
- Country
- The Netherlands
- ProdList
- 4996
- Advantage
- 67
View Lastest Price from 1-METHYL-5-NITRO-1H-INDAZOLE manufacturers
- Product
- 1-METHYL-5-NITRO-1H-INDAZOLE 5228-49-9
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11
- Product
- 1-METHYL-5-NITRO-1H-INDAZOLE 5228-49-9
- Price
- US $0.10/KG
- Min. Order
- 1KG
- Purity
- 95%-99%
- Supply Ability
- 1kg; 50kg; 500kg
- Release date
- 2019-12-24