ChemicalBook > CAS DataBase List > 1-METHYL-5-NITRO-1H-INDAZOLE

1-METHYL-5-NITRO-1H-INDAZOLE

Product Name
1-METHYL-5-NITRO-1H-INDAZOLE
CAS No.
5228-49-9
Chemical Name
1-METHYL-5-NITRO-1H-INDAZOLE
Synonyms
SW-35;SWF-35;1-METHYL-5-NITROINDAZOLE;1-METHYL-5-NITRO-1H-INDAZOLE;5-Nitro-1-methyl-1H-indazole;1H-Indazole, 1-methyl-5-nitro-;1-METHYL-5-NITRO-1H-INDAZOLE, 98+%;1-methyl-5-nitro-1H-indazole, 1-methyl-5-nitroindazole, 1-methyl-5-nitro-1H-indazole, 1-Methyl-5-nitro-1H-indazol, 1-methyl-5-nitro-indazole, 1-Methyl-5-nitro-indazol, 1-Methyl-5-nitroindazol
CBNumber
CB1239421
Molecular Formula
C8H7N3O2
Formula Weight
177.16
MOL File
5228-49-9.mol
More
Less

1-METHYL-5-NITRO-1H-INDAZOLE Property

Melting point:
161-162°C
Boiling point:
332.9±15.0 °C(Predicted)
Density 
1.42±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
form 
solid
pka
-0.82±0.30(Predicted)
color 
yellow
BRN 
168080
CAS DataBase Reference
5228-49-9(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
20/22-68
Safety Statements 
22-36/37
RIDADR 
2811
HazardClass 
IRRITANT
PackingGroup 
II
HS Code 
2933998090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

More
Less

N-Bromosuccinimide Price

TRC
Product number
M218795
Product name
1-Methyl-5-nitro-1H-indazole
Packaging
500mg
Price
$75
Updated
2021/12/16
AK Scientific
Product number
W6706
Product name
1-Methyl-5-nitro-1H-indazole
Packaging
5g
Price
$161
Updated
2021/12/16
Apolloscientific
Product number
OR14146
Product name
1-Methyl-5-nitro-1H-indazole
Packaging
250mg
Price
$15
Updated
2021/12/16
SynQuest Laboratories
Product number
4H54-1-V8
Product name
1-Methyl-5-nitro-1H-indazole
Packaging
250mg
Price
$16
Updated
2021/12/16
Apolloscientific
Product number
OR14146
Product name
1-Methyl-5-nitro-1H-indazole
Packaging
1g
Price
$28
Updated
2021/12/16
More
Less

1-METHYL-5-NITRO-1H-INDAZOLE Chemical Properties,Usage,Production

Synthesis

5401-94-5

74-88-4

5228-48-8

5228-49-9

GENERAL METHOD: Cesium carbonate (12.26 mmol) was added to a solution of 5-nitroindazole (6.13 mmol) in tetrahydrofuran (THF; 25 mL) at 0 °C. The reaction mixture was stirred at 0 °C for 15 min before iodomethane or allyl bromide (6.13 mmol) was added dropwise. The progress of the reaction was monitored by thin layer chromatography (TLC) until the starting material completely disappeared. After completion of the reaction, the mixture was concentrated. The crude product was dissolved in ethyl acetate (EtOAc; 50 mL), washed sequentially with water and brine, and the organic phase was dried over anhydrous magnesium sulfate (MgSO?). The solvent was removed by evaporation under reduced pressure, and the resulting residue was purified by silica gel column chromatography with ethyl acetate/hexane (3:7, v/v) as eluent to afford 1-alkyl-5-nitroindazole and 2-alkyl-5-nitroindazole, respectively.

References

[1] Synthetic Communications, 2015, vol. 45, # 17, p. 2005 - 2013
[2] Tetrahedron, 2008, vol. 64, # 28, p. 6711 - 6723
[3] Patent: US2014/371219, 2014, A1. Location in patent: Paragraph 0659; 0660; 0661
[4] Patent: WO2016/57834, 2016, A1. Location in patent: Paragraph 000406

1-METHYL-5-NITRO-1H-INDAZOLE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

1-METHYL-5-NITRO-1H-INDAZOLE Suppliers

China 104 France 1 Germany 2 India 3 The Netherlands 2 United Kingdom 6 United States 22 Global 140
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
Accela ChemBio Inc.
Tel
+1-858-6993322
Fax
(+1)-858-876-1948
Email
info@accelachem.com
Country
United States
ProdList
21193
Advantage
58
Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63687
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
52923
Advantage
58
Aceschem Inc.
Tel
+1-817863-6948 +1-（817）863-6948
Email
sales@aceschem.com
Country
United States
ProdList
19632
Advantage
58
Synthonix Inc
Tel
--
Fax
--
Email
info@synthonix.com
Country
United States
ProdList
6872
Advantage
58
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
SynQuest Laboratories, Inc.
Tel
--
Fax
--
Email
info@synquestlabs.com
Country
United States
ProdList
6871
Advantage
62
Frontier Scientific, Inc.
Tel
--
Fax
--
Email
sales@frontiersci.com
Country
United States
ProdList
6222
Advantage
86
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
Sphinx Scientific Laboratory, LLC
Tel
--
Fax
--
Email
sales@sphinxscientificlab.com
Country
United States
ProdList
3343
Advantage
50
Anichem LLC
Tel
--
Fax
--
Email
sales@anichemllc.com
Country
United States
ProdList
4112
Advantage
34
Aces Pharma, Inc.
Tel
--
Fax
--
Email
sales@acespharma.com
Country
United States
ProdList
959
Advantage
50
OChem Incorporation
Tel
--
Fax
--
Email
sales@ocheminc.com
Country
United States
ProdList
6501
Advantage
60
American Custom Chemicals Corporation
Tel
--
Fax
--
Email
sales@acccorporation.com
Country
United States
ProdList
6820
Advantage
51
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6962
Advantage
56
Ryan Scientific, Inc.
Tel
--
Fax
--
Email
ryan.reichlyn@ryansci.com
Country
United States
ProdList
6439
Advantage
60
Alfa Aesar
Tel
--
Fax
--
Email
tech@alfa.com
Country
United States
ProdList
6814
Advantage
81
Chem-Impex International, Inc.
Tel
--
Fax
--
Country
United States
ProdList
6730
Advantage
64
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
Advantage
47
HONEST JOY HOLDINGS LIMITED
Tel
--
Fax
--
Email
sales@honestjoy.cn
Country
United States
ProdList
6675
Advantage
54
J & W PharmLab, LLC
Tel
--
Fax
--
Email
services@jwpharmlab.com
Country
United States
ProdList
4156
Advantage
63
More
Less

View Lastest Price from 1-METHYL-5-NITRO-1H-INDAZOLE manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
1-METHYL-5-NITRO-1H-INDAZOLE 5228-49-9
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11
Career Henan Chemical Co
Product
1-METHYL-5-NITRO-1H-INDAZOLE 5228-49-9
Price
US $0.10/KG
Min. Order
1KG
Purity
95%-99%
Supply Ability
1kg; 50kg; 500kg
Release date
2019-12-24

5228-49-9, 1-METHYL-5-NITRO-1H-INDAZOLERelated Search:

tert-butyl 4-(4-broMothiazol-2-yl)piperazine-1-carboxylate (6-Methylpyridazin-3-yl)MethanaMine dihydrochloride No Chinese name rac-4-(6-chloro-2-oxo-2,3-dihydro-1H-indol-3-yl)-piperidine-1-carboxylic acid tert-butyl 5-METHYL-4,5,6,7-TETRAHYDRO[1,3]THIAZOLO[5,4-C]PYRIDIN-2-AMINE 2,4-dichloro-7H-Pyrrolo[2,3-d]pyriMidine-7-carboxylic acid 1,1-diMethylethyl ester 5-BROMO-2-METHYL-3-NITROPHENYL METHYLCARBOXYLATE 1H-Pyrrolo[2,3-b]pyridine, 2-methyl-1-(phenylsulfonyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)- Pyrrolidine-3-carboxaMide hydrochloride 5-Bromoindazole (2R,5S)-tert-butyl 4-benzyl-2,5-diMethylpiperazine-1-carboxylate 2-cyclopylcyclopropane-1-carboxylic acid 4-FLUORO-2-HYDROXYBENZALDEHYDE 4-CYANO-7-AZAINDOLE 5-Bromoindole (+/-)-BOC-ALPHA-PHOSPHONOGLYCINE TRIMETHYL ESTER 1-Boc-4-(Hydroxymethyl)-4-methyl-piperidine 4-CYANOPYRAZOLE

  • 1-METHYL-5-NITROINDAZOLE
  • 1-METHYL-5-NITRO-1H-INDAZOLE
  • 1-methyl-5-nitro-1H-indazole, 1-methyl-5-nitroindazole, 1-methyl-5-nitro-1H-indazole, 1-Methyl-5-nitro-1H-indazol, 1-methyl-5-nitro-indazole, 1-Methyl-5-nitro-indazol, 1-Methyl-5-nitroindazol
  • 1-METHYL-5-NITRO-1H-INDAZOLE, 98+%
  • 5-Nitro-1-methyl-1H-indazole
  • 1H-Indazole, 1-methyl-5-nitro-
  • SWF-35
  • SW-35
  • 5228-49-9
  • Indazoles