METHYLENEDIAMINE DIHYDROCHLORIDE Property

Melting point:

>300°C

storage temp. 

2-8°C

solubility 

Methanol (Slightly, Sonicated), Water (Sparingly)

form 

Solid

color 

White to Off-White

BRN 

3664689

CAS DataBase Reference

57166-92-4

EPA Substance Registry System

Methylenediamine dihydrochloride (57166-92-4)

Safety

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

METHYLENEDIAMINE DIHYDROCHLORIDE Chemical Properties,Usage,Production

Uses

The Dihydrochloride salt of Methanediamine (M260225) in used in synthesizing FK-506 3’-Methyl Ether (F370010).

General Description

White granular solid. Decomposes at approximately 275°F (changes to white puffy solid), then slowly darkens until total decomposition at approximately 464°F.

Air & Water Reactions

Water soluble.

Reactivity Profile

An acidic organic salt of an amine. In aqueous solution, behaves as an acid. Materials in this group are generally soluble in water. The resulting solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible. Many of these compounds catalyze organic reactions.

Fire Hazard

Flash point data for METHYLENEDIAMINE DIHYDROCHLORIDE are not available; however, METHYLENEDIAMINE DIHYDROCHLORIDE is probably combustible.