ChemicalBook > CAS DataBase List > Triethylene Glycol 2-Bromoethyl Methyl Ether

Triethylene Glycol 2-Bromoethyl Methyl Ether

Product Name
Triethylene Glycol 2-Bromoethyl Methyl Ether
CAS No.
110429-45-3
Chemical Name
Triethylene Glycol 2-Bromoethyl Methyl Ether
Synonyms
mPEG4-Br;m-PEG4-bromo;m-PEG4-bromide;Br-(CH2CH2O)4-Me;Bromo-PEG4-methoxy;Methyl-PEG4-bromide;1-Bromo-3,6,9,12-tetraoxatridecane;13-Bromo-2,5,8,11-tetraoxatridecane;2,5,8,11-Tetraoxatridecane, 13-bromo-;Triethylene Glycol 2-Bromoethyl Methyl Ether
CBNumber
CB12469761
Molecular Formula
C9H19BrO4
Formula Weight
271.15
MOL File
110429-45-3.mol
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Triethylene Glycol 2-Bromoethyl Methyl Ether Property

Boiling point:
296.3±25.0 °C(Predicted)
Density 
1.256±0.06 g/cm3(Predicted)
refractive index 
1.4620 to 1.4660
storage temp. 
2-8°C
form 
clear liquid
color 
White to Yellow to Green
CAS DataBase Reference
110429-45-3
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Safety

HS Code 
2909.19.6000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
T2634
Product name
Triethylene Glycol 2-Bromoethyl Methyl Ether
Purity
>95.0%(GC)
Packaging
5g
Price
$198
Updated
2024/03/01
TCI Chemical
Product number
T2634
Product name
Triethylene Glycol 2-Bromoethyl Methyl Ether
Purity
>95.0%(GC)
Packaging
25g
Price
$588
Updated
2024/03/01
TRC
Product number
T776665
Product name
Triethylene Glycol 2-Bromoethyl Methyl Ether
Packaging
50mg
Price
$45
Updated
2021/12/16
TRC
Product number
T776665
Product name
Triethylene Glycol 2-Bromoethyl Methyl Ether
Packaging
100mg
Price
$60
Updated
2021/12/16
Activate Scientific
Product number
AS103896
Product name
mPEG4-Br
Purity
95+%
Packaging
1g
Price
$146
Updated
2021/12/16
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Triethylene Glycol 2-Bromoethyl Methyl Ether Chemical Properties,Usage,Production

Description

m-PEG4-bromide is a PEG linker containing a bromide group. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.

Biological Activity

Triethylene Glycol 2-Bromoethyl Methyl Ether is a cleavable ADC linker for the synthesis of antibody drug conjugates (ADCs) of trastuzumab (HY-P9907). It was placed distal to the monomethyl auristatin E (MMAE) payload to generate ADCs with altered hydrophilicity, antigen binding and in vitro potency. Tetraethylene glycol monotosylate can also be used as a linker of PROTAC, which can be used for the synthesis of PROTAC.

in vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

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Triethylene Glycol 2-Bromoethyl Methyl Ether Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Triethylene Glycol 2-Bromoethyl Methyl Ether manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
m-PEG4-Br 110429-45-3
Price
US $0.00/g
Min. Order
25g
Purity
>98.00%
Supply Ability
25g
Release date
2024-03-27
Career Henan Chemical Co
Product
Triethylene Glycol 2-Bromoethyl Methyl Ether 110429-45-3
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kg
Release date
2020-01-09

110429-45-3, Triethylene Glycol 2-Bromoethyl Methyl EtherRelated Search:

Phosphorus oxybromide m-PEG4-aldehyde mPEG3-CH2COOH Triethylene Glycol Mono(2-propynyl) Ether 1-{2-[2-(2-{2-[2-(2-Bromo-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-2-methoxy-ethane mPEG12-Br m-PEG5-bromide Bromo-PEG3-Acid 25-Bromo-2,5,8,11,14,17,20,23-octaoxapentacosane m-PEG9-bromide NONAETHYLENE GLYCOL MONOMETHYL ETHER Methyl-PEG12-bromide MPEG3-CH2CH2COOH 2,5,8,11,14-pentaoxahexadecan-16-oic acid 2,5,8,11,14,17,20-Heptaoxadocosan-22-amine Methyl-PEG10-azide Methyl-PEG9-bromide m-PEG6-bromide

  • Triethylene Glycol 2-Bromoethyl Methyl Ether
  • m-PEG4-bromide
  • Methyl-PEG4-bromide
  • 2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethyl Bromide 1-Bromo-3,6,9,12-tetraoxatridecane
  • Bromo-PEG4-methoxy
  • 13-Bromo-2,5,8,11-tetraoxatridecane
  • mPEG4-Br
  • 2,5,8,11-Tetraoxatridecane, 13-bromo-
  • 1-Bromo-3,6,9,12-tetraoxatridecane
  • 2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethyl Bromide
  • Br-(CH2CH2O)4-Me
  • m-PEG4-bromo
  • mPEG4-Br/2,5,8,11-Tetraoxatridecane, 13-bromo-
  • 1-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]-2-methoxyethane
  • 110429-45-3
  • C9H19BrO4

    • Cleavable

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