6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)chroman, 97%

Product Name: 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)chroman, 97%
CAS No.: 1002727-88-9
Chemical Name: 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)chroman, 97%
Synonyms: Chroman-6-boronic acid, pinacol ester;Chromane-6-boronic Acid Pinacol Ester;CHROMAN-6-YLBORONIC ACID PINACOL ESTER;Chroman-6-boronic acid, pinacol ester 99%;2-(ChroMan-6-yl)-4,4,5,5-tetraMethyl-1,3,2-dioxaborolane;6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)chroman, 97%;6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)chroman, 97%;2-(3,4-dihydro-2h-chromen-6-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;2H-1-Benzopyran, 3,4-dihydro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-;3,4-Dihydro-2H-chromene-6-boronic acid, pinacol ester, 3,4-Dihydro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-chromene
CBNumber: CB12527946
Molecular Formula: C15H21BO3
Formula Weight: 260.14
MOL File: 1002727-88-9.mol

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6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)chroman, 97% Property

Boiling point:: 373.5±31.0 °C(Predicted)
Density: 1.08±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
form: powder
color: Off-white
InChI: InChI=1S/C15H21BO3/c1-14(2)15(3,4)19-16(18-14)12-7-8-13-11(10-12)6-5-9-17-13/h7-8,10H,5-6,9H2,1-4H3
InChIKey: NDSHAELUPJMEBM-UHFFFAOYSA-N
SMILES: C1OC2=CC=C(B3OC(C)(C)C(C)(C)O3)C=C2CC1

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Safety

HS Code: 28402000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: C428890
Product name: 2-(Chroman-6-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
Packaging: 50mg
Price: $45
Updated: 2021/12/16

Apolloscientific

Product number: OR16520
Product name: Chroman-6-boronic acid, pinacol ester
Purity: 99%
Packaging: 1g
Price: $82
Updated: 2021/12/16

SynQuest Laboratories

Product number: 6H60-1-17
Product name: Chroman-6-boronic acid, pinacol ester
Purity: 99%
Packaging: 1g
Price: $96
Updated: 2021/12/16

Apolloscientific

Product number: OR16520
Product name: Chroman-6-boronic acid, pinacol ester
Purity: 99%
Packaging: 250mg
Price: $33
Updated: 2021/12/16

SynQuest Laboratories

Product number: 6H60-1-17
Product name: Chroman-6-boronic acid, pinacol ester
Purity: 99%
Packaging: 250mg
Price: $39
Updated: 2021/12/16

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6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)chroman, 97% Chemical Properties,Usage,Production

Synthesis

67856-45-5

73183-34-3

1002727-88-9

Step 3: 6-Iodobenzodihydropyran (1.0 g, 3.85 mmol), pinacol ester of bisboronic acid (1.22 g, 4.81 mmol) and potassium acetate (1.10 g, 11.5 mmol) were dissolved in DMF (36 mL), and the solution was degassed by argon for 5 min. Subsequently, PdCl2(dppf)-DCM complex (314 mg, 0.38 mmol) was added and the reaction mixture was again degassed for 5 min. The reaction system was heated to 95 °C with continuous stirring for 5 hours. After completion of the reaction, it was cooled to room temperature. The crude reaction mixture was diluted with water and extracted three times with ethyl acetate (3 x 100 mL). The organic phases were combined and washed sequentially with water (100 mL) and brine (100 mL). The organic layer was dried over anhydrous magnesium sulfate, filtered and concentrated. The crude product was further purified by the CombiFlash system using gradient elution with ethyl acetate/hexane to afford the target product 3,4-dihydrochromene-6-boronic acid ester (840 mg, 84% yield).

References

[1] Patent: WO2009/62285, 2009, A1. Location in patent: Page/Page column 66-67
[2] Patent: WO2009/62308, 2009, A1. Location in patent: Page/Page column 76
[3] Patent: WO2009/62288, 2009, A1. Location in patent: Page/Page column 72-73

6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)chroman, 97% Preparation Products And Raw materials

Raw materials

Preparation Products

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6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)chroman, 97% Suppliers

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View Lastest Price from 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)chroman, 97% manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: 6-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)chroMan 1002727-88-9
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-27

Career Henan Chemical Co

Product: 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)chroman, 97% 1002727-88-9
Price: US $1.00/kg
Min. Order: 1kg
Purity: 95%-99%
Supply Ability: 100kg
Release date: 2018-12-22

1002727-88-9, 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)chroman, 97%Related Search:

Dibenzofuran 1-METHYL-4-[5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABORALAN-2-YL)PYRIDINE-2-YL]PIPERAZINE N-(4-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)acetaMide 2-CYANOPYRIDINE-4-BORONIC ACID PINACOL ESTER 6-FLUOROPYRIDINE-2-BORONIC ACID PINACOL ESTER 1-(5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDIN-2-YL)PIPERAZINE

6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)chroman, 97%

3,4-Dihydro-2H-chromene-6-boronic acid, pinacol ester, 3,4-Dihydro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-chromene

Chroman-6-boronic acid, pinacol ester

2-(ChroMan-6-yl)-4,4,5,5-tetraMethyl-1,3,2-dioxaborolane

Chroman-6-boronic acid, pinacol ester 99%

2-(3,4-dihydro-2h-chromen-6-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

CHROMAN-6-YLBORONIC ACID PINACOL ESTER

2H-1-Benzopyran, 3,4-dihydro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-

Chromane-6-boronic Acid Pinacol Ester

6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)chroman, 97%

1002727-88-9

Organic boronic acid