(2-Aminophenyl)dimethylphosphine Oxide

Product Name: (2-Aminophenyl)dimethylphosphine Oxide
CAS No.: 1197953-47-1
Chemical Name: (2-Aminophenyl)dimethylphosphine Oxide
Synonyms: Buglitinibintermediate;2-(Dimethyloxonyl)aniline;Brigatinib intermediates;2-(Dimethylphosphinyl)aniline;2-(diMethylphosphoryl)aniline;2- (dimethylphosphino) aniline;2-(diMethylphosphoryl)aniline HCl;2-(diMethylphosphoryl)benzenaMine;2-(Dimethylphosphinyl)benzenamine;3-(Dimethylphosphinyl)benzenamine
CBNumber: CB12595392
Molecular Formula: C8H12NOP
Formula Weight: 169.16
MOL File: 1197953-47-1.mol

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(2-Aminophenyl)dimethylphosphine Oxide Property

Boiling point:: 367.5±34.0 °C(Predicted)
Density: 1.11±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
pka: 1.10±0.10(Predicted)
InChI: InChI=1S/C8H12NOP/c1-11(2,10)8-6-4-3-5-7(8)9/h3-6H,9H2,1-2H3
InChIKey: DHHGHQKIKXKQGJ-UHFFFAOYSA-N
SMILES: C1(N)=CC=CC=C1P(C)(C)=O

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Safety

RIDADR: UN2811
HS Code: 2923900090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: A638018
Product name: (2-Aminophenyl)dimethylphosphineOxide
Packaging: 100mg
Price: $60
Updated: 2021/12/16

TRC

Product number: A638018
Product name: (2-Aminophenyl)dimethylphosphineOxide
Packaging: 500mg
Price: $110
Updated: 2021/12/16

AK Scientific

Product number: Z3963
Product name: (2-Aminophenyl)dimethylphosphineoxide
Packaging: 1g
Price: $134
Updated: 2021/12/16

Apolloscientific

Product number: OR49045
Product name: 2-Dimethylphosphorylaniline
Packaging: 1g
Price: $169
Updated: 2021/12/16

AK Scientific

Product number: Z3963
Product name: (2-Aminophenyl)dimethylphosphineoxide
Packaging: 10g
Price: $458
Updated: 2021/12/16

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(2-Aminophenyl)dimethylphosphine Oxide Chemical Properties,Usage,Production

Uses

(2-Aminophenyl)dimethylphosphine Oxide is mainly used as a raw material or reagent for organic synthesis and can be used to prepare other compounds such as phosphine oxide derivatives and pyrimidine derivatives.

Synthesis

(2-Aminophenyl)dimethylphosphine Oxide is prepared by the reaction of 2-Iodoaniline and Dimethylphosphine oxide. The specific synthesis steps are as follows:
To a solution of 2-iodoaniline ( 1.0 eq) and dimethylphosphine oxide (1.1 eq) in DMF were added potassium phosphate ( 1.1 eq) and palladium acetate/Xantphos (catalytic). The reaction was stirred at 150 °C for 3 hours and cooled to room temperature. The solvent was evaporated and the residue was worked up with DCM/water. The crude product was purified with a column(EtOAc/MeOH 10: 1 ) to give 1 as a brown solid (80percent yield).

(2-Aminophenyl)dimethylphosphine Oxide Preparation Products And Raw materials

Raw materials

Preparation Products

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(2-Aminophenyl)dimethylphosphine Oxide Suppliers

China 175 India 1 United Kingdom 1 United States 5 Global 182

Chongqing Acemol Technology Co.,Ltd

Tel: 023-86822659，企业QQ3004125759 18611316925
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View Lastest Price from (2-Aminophenyl)dimethylphosphine Oxide manufacturers

Henan Fengda Chemical Co., Ltd

Product: 2-(diMethylphosphoryl)aniline 1197953-47-1
Price: US $5.00-0.10/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-09

Henan Aochuang Chemical Co.,Ltd.

Product: 2-(diMethylphosphoryl)aniline 1197953-47-1
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-08

Zhuozhou Wenxi import and Export Co., Ltd

Product: 2-(diMethylphosphoryl)aniline 1197953-47-1
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

1197953-47-1, (2-Aminophenyl)dimethylphosphine OxideRelated Search:

Dichloroethane (2-((2,5-Dichloropyrimidin-4-yl)amino)phenyl)dimethylphosphine oxide 2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline Brigatinib AP26113

2-(diMethylphosphoryl)aniline

2-(diMethylphosphoryl)benzenaMine

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Benzenamine, 2-(dimethylphosphinyl)-

2-(Dimethylphosphinyl)benzenamine

2-(Dimethylphosphinyl)benzeneamine

2-(Dimethylphosphinyl)aniline

2-(diMethylphosphoryl)aniline HCl

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Buglitinibintermediate

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3-(Dimethylphosphinyl)benzenamine

1197953-47-1

C8H12NOP