2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline

Product Name: 2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline
CAS No.: 761440-75-9
Chemical Name: 2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline
Synonyms: 2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline;WDQZQPCYVLHWRA;Brigatinib Impurity 3;2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidyl]aniline;2-Methoxy-4-[4-(-methylpiperazine-1-yl)piperidin-1-yl]amine;2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)anilin;2-Methoxy-4-(4-(4-Methylpiperazin-1-yl)piperidin-1-yl)benzenaMine;2-Methoxy-4-[4-(4-Methyl-1-piperazinyl)-1-piperidinyl]-BenzenaMine;[2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amine;Benzenamine, 2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]-
CBNumber: CB82473938
Molecular Formula: C17H28N4O
Formula Weight: 304.43
MOL File: 761440-75-9.mol

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2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline Property

Boiling point:: 479.3±45.0 °C(Predicted)
Density: 1.126±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 8.14±0.42(Predicted)
InChI: InChI=1S/C17H28N4O/c1-19-9-11-21(12-10-19)14-5-7-20(8-6-14)15-3-4-16(18)17(13-15)22-2/h3-4,13-14H,5-12,18H2,1-2H3
InChIKey: WDQZQPCYVLHWRA-UHFFFAOYSA-N
SMILES: C1(N)=CC=C(N2CCC(N3CCN(C)CC3)CC2)C=C1OC

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

AK Scientific

Product number: J56928
Product name: 2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline
Packaging: 5g
Price: $205
Updated: 2021/12/16

Matrix Scientific

Product number: 090161
Product name: 2-Methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)aniline
Purity: 95+%
Packaging: 250mg
Price: $243
Updated: 2021/12/16

ChemScene

Product number: CS-M0379
Product name: 2-Methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)aniline
Purity: 98.99%
Packaging: 5g
Price: $244
Updated: 2021/12/16

ChemScene

Product number: CS-M0379
Product name: 2-Methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)aniline
Purity: 98.99%
Packaging: 10g
Price: $405
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0388321
Product name: 2-METHOXY-4-(4-(4-METHYLPIPERAZIN-1-YL)PIPERIDIN-1-YL)ANILINE
Purity: 95.00%
Packaging: 5MG
Price: $500.92
Updated: 2021/12/16

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2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline Chemical Properties,Usage,Production

Description

2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline is a cycloalkylamine analogue that can be used as a component of organic synthesis intermediates for the synthesis of the active compound ASP3026. ASP3026 is an orally available receptor tyrosine kinase anaplastic lymphoma kinase (ALK) small molecule inhibitor with promising anti-tumour and apoptosis-inducing effects, which has been used in the study of solid tumours, B-cell lymphomas, advanced malignant tumours, interstitial lymphoma kinase-positive and proto-oncogene tyrosine protein kinase ROS-positive therapy.

Uses

[2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amine is an intermediate of Brigatinib which is a medicine used to treat cancer that suppresses epidermal growth factor receptor (EGFR) and anaplastic lymphoma kinase (ALK).

2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline Suppliers

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Shanghai Hope Chem Co., Ltd.，

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Shanghai Sunway Pharmaceutical Technology Co., Ltd

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View Lastest Price from 2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline manufacturers

Enki Biopharmaceuticals (Shanghai) Limited

Product: 2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline 761440-75-9
Price: US $0.00-0.00/kg
Min. Order: 5kg
Purity: 99.0%
Supply Ability: 100
Release date: 2023-11-26

Henan Fengda Chemical Co., Ltd

Product: 2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline 761440-75-9
Price: US $5.00-0.10/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-09

Henan Aochuang Chemical Co.,Ltd.

Product: [2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amine 761440-75-9
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-30

761440-75-9, 2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]anilineRelated Search:

(2-((2,5-Dichloropyrimidin-4-yl)amino)phenyl)dimethylphosphine oxide Brigatinib AP26113 2-(diMethylphosphoryl)aniline 1-(4-TRIFLUOROMETHYLPHENYL)PIPERAZINE 2-Methylpiperazine 1-Methylpiperazine

[2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amine

2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline

2-Methoxy-4-(4-(4-Methylpiperazin-1-yl)piperidin-1-yl)benzenaMine

2-Methoxy-4-[4-(4-Methyl-1-piperazinyl)-1-piperidinyl]-BenzenaMine

2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)anilin

2-methoxy-4- [4- (4-methyl-1-piperazinyl) -1-piperazinyl] - aniline hydrochloride

2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidyl]aniline

WDQZQPCYVLHWRA

Benzenamine, 2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]-

[2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amine ISO 9001：2015 REACH

[2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amine,761440-75-9

2-methoxy-4-[4-(4-methy l-1-piperazinyl)-1-pipe razinyl]-aniline hydrochlorid

Aniline 2-methoxy-4 - [4 - (4-methyl-1-piperazinyl) - 1-piperazinyl] - hydrochloride

2- methoxy -4-[4-(4- methylpiperazine -1- yl) piperidin -1- yl] aniline *

Brigatinib Impurity 3

2-Methoxy-4-[4-(-methylpiperazine-1-yl)piperidin-1-yl]amine

761440-75-9

C17H28N4O

761440-75-9