ChemicalBook > CAS DataBase List > 2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline

2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline

Product Name
2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline
CAS No.
761440-75-9
Chemical Name
2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline
Synonyms
2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline;WDQZQPCYVLHWRA;Brigatinib Impurity 3;2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidyl]aniline;2-Methoxy-4-[4-(-methylpiperazine-1-yl)piperidin-1-yl]amine;2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)anilin;2-Methoxy-4-(4-(4-Methylpiperazin-1-yl)piperidin-1-yl)benzenaMine;2-Methoxy-4-[4-(4-Methyl-1-piperazinyl)-1-piperidinyl]-BenzenaMine;[2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amine;Benzenamine, 2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]-
CBNumber
CB82473938
Molecular Formula
C17H28N4O
Formula Weight
304.43
MOL File
761440-75-9.mol
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2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline Property

Boiling point:
479.3±45.0 °C(Predicted)
Density 
1.126±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
8.14±0.42(Predicted)
Appearance
Light brown to black Solid
InChI
InChI=1S/C17H28N4O/c1-19-9-11-21(12-10-19)14-5-7-20(8-6-14)15-3-4-16(18)17(13-15)22-2/h3-4,13-14H,5-12,18H2,1-2H3
InChIKey
WDQZQPCYVLHWRA-UHFFFAOYSA-N
SMILES
C1(N)=CC=C(N2CCC(N3CCN(C)CC3)CC2)C=C1OC
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

AK Scientific
Product number
J56928
Product name
2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline
Packaging
5g
Price
$205
Updated
2021/12/16
Matrix Scientific
Product number
090161
Product name
2-Methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)aniline
Purity
95+%
Packaging
250mg
Price
$243
Updated
2021/12/16
ChemScene
Product number
CS-M0379
Product name
2-Methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)aniline
Purity
98.99%
Packaging
5g
Price
$244
Updated
2021/12/16
ChemScene
Product number
CS-M0379
Product name
2-Methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)aniline
Purity
98.99%
Packaging
10g
Price
$405
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0388321
Product name
2-METHOXY-4-(4-(4-METHYLPIPERAZIN-1-YL)PIPERIDIN-1-YL)ANILINE
Purity
95.00%
Packaging
5MG
Price
$500.92
Updated
2021/12/16
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2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline Chemical Properties,Usage,Production

Description

2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline is a cycloalkylamine analogue that can be used as a component of organic synthesis intermediates for the synthesis of the active compound ASP3026. ASP3026 is an orally available receptor tyrosine kinase anaplastic lymphoma kinase (ALK) small molecule inhibitor with promising anti-tumour and apoptosis-inducing effects, which has been used in the study of solid tumours, B-cell lymphomas, advanced malignant tumours, interstitial lymphoma kinase-positive and proto-oncogene tyrosine protein kinase ROS-positive therapy.

Uses

[2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amine is an intermediate of Brigatinib which is a medicine used to treat cancer that suppresses epidermal growth factor receptor (EGFR) and anaplastic lymphoma kinase (ALK).

2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline Suppliers

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View Lastest Price from 2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline manufacturers

Enki Biopharmaceuticals (Shanghai) Limited
Product
2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline 761440-75-9
Price
US $0.00-0.00/kg
Min. Order
5kg
Purity
99.0%
Supply Ability
100
Release date
2023-11-26
Henan Aochuang Chemical Co.,Ltd.
Product
[2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amine 761440-75-9
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-30
Shaanxi Dideu New Materials Co. Ltd
Product
2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline 761440-75-9
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000KGS
Release date
2025-03-05

761440-75-9, 2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]anilineRelated Search:

(2-((2,5-Dichloropyrimidin-4-yl)amino)phenyl)dimethylphosphine oxide Brigatinib AP26113 2-(diMethylphosphoryl)aniline 1-(4-TRIFLUOROMETHYLPHENYL)PIPERAZINE 2-Methylpiperazine 1-Methylpiperazine

  • [2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amine
  • 2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline
  • 2-Methoxy-4-(4-(4-Methylpiperazin-1-yl)piperidin-1-yl)benzenaMine
  • 2-Methoxy-4-[4-(4-Methyl-1-piperazinyl)-1-piperidinyl]-BenzenaMine
  • 2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)anilin
  • 2-methoxy-4- [4- (4-methyl-1-piperazinyl) -1-piperazinyl] - aniline hydrochloride
  • 2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidyl]aniline
  • WDQZQPCYVLHWRA
  • Benzenamine, 2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]-
  • [2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amine ISO 9001：2015 REACH
  • [2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amine,761440-75-9
  • 2-methoxy-4-[4-(4-methy l-1-piperazinyl)-1-pipe razinyl]-aniline hydrochlorid
  • Aniline 2-methoxy-4 - [4 - (4-methyl-1-piperazinyl) - 1-piperazinyl] - hydrochloride
  • 2- methoxy -4-[4-(4- methylpiperazine -1- yl) piperidin -1- yl] aniline *
  • 2-Methoxy-4-[4-(-methylpiperazine-1-yl)piperidin-1-yl]amine
  • Brigatinib Impurity 3
  • 2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperazin-1-yl]aniline hydrochloride
  • 761440-75-9
  • C17H28N4O
  • 761440-75-9