2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline
- Product Name
- 2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline
- CAS No.
- 761440-75-9
- Chemical Name
- 2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline
- Synonyms
- 2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline;WDQZQPCYVLHWRA;Brigatinib Impurity 3;2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidyl]aniline;2-Methoxy-4-[4-(-methylpiperazine-1-yl)piperidin-1-yl]amine;2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)anilin;2-Methoxy-4-(4-(4-Methylpiperazin-1-yl)piperidin-1-yl)benzenaMine;2-Methoxy-4-[4-(4-Methyl-1-piperazinyl)-1-piperidinyl]-BenzenaMine;[2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amine;Benzenamine, 2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]-
- CBNumber
- CB82473938
- Molecular Formula
- C17H28N4O
- Formula Weight
- 304.43
- MOL File
- 761440-75-9.mol
2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline Property
- Boiling point:
- 479.3±45.0 °C(Predicted)
- Density
- 1.126±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 8.14±0.42(Predicted)
- InChI
- InChI=1S/C17H28N4O/c1-19-9-11-21(12-10-19)14-5-7-20(8-6-14)15-3-4-16(18)17(13-15)22-2/h3-4,13-14H,5-12,18H2,1-2H3
- InChIKey
- WDQZQPCYVLHWRA-UHFFFAOYSA-N
- SMILES
- C1(N)=CC=C(N2CCC(N3CCN(C)CC3)CC2)C=C1OC
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- CS-M0379
- Product name
- 2-Methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)aniline
- Purity
- 98.99%
- Packaging
- 1g
- Price
- $81
- Updated
- 2021/12/16
- Product number
- J56928
- Product name
- 2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline
- Packaging
- 5g
- Price
- $205
- Updated
- 2021/12/16
- Product number
- 090161
- Product name
- 2-Methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)aniline
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $243
- Updated
- 2021/12/16
- Product number
- CS-M0379
- Product name
- 2-Methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)aniline
- Purity
- 98.99%
- Packaging
- 5g
- Price
- $244
- Updated
- 2021/12/16
- Product number
- CS-M0379
- Product name
- 2-Methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)aniline
- Purity
- 98.99%
- Packaging
- 10g
- Price
- $405
- Updated
- 2021/12/16
2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline Chemical Properties,Usage,Production
Description
2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline is a cycloalkylamine analogue that can be used as a component of organic synthesis intermediates for the synthesis of the active compound ASP3026. ASP3026 is an orally available receptor tyrosine kinase anaplastic lymphoma kinase (ALK) small molecule inhibitor with promising anti-tumour and apoptosis-inducing effects, which has been used in the study of solid tumours, B-cell lymphomas, advanced malignant tumours, interstitial lymphoma kinase-positive and proto-oncogene tyrosine protein kinase ROS-positive therapy.
Uses
[2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amine is an intermediate of Brigatinib which is a medicine used to treat cancer that suppresses epidermal growth factor receptor (EGFR) and anaplastic lymphoma kinase (ALK).
2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline Preparation Products And Raw materials
Raw materials
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View Lastest Price from 2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline manufacturers
- Product
- 2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline 761440-75-9
- Price
- US $0.00-0.00/kg
- Min. Order
- 5kg
- Purity
- 99.0%
- Supply Ability
- 100
- Release date
- 2023-11-26
- Product
- 2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline 761440-75-9
- Price
- US $5.00-0.10/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-09
- Product
- [2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amine 761440-75-9
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-30