Amorolfine hydrochloride

Product Name: Amorolfine hydrochloride
CAS No.: 106614-68-0
Chemical Name: Amorolfine hydrochloride
Synonyms: AMOROLFINE HCL;Amorolfine hydrochloride;2,6-Dimethyl-4-(2-methyl-3-(4-(tert-pentyl)phenyl)propyl)morpholine hydrochloride;(+/-)-cis-2,6-dimethyl-4-[2-methyl-3-(p-tert-pentylphenyl)propyl]morpholine hydrochloride;Morpholine, 4-[3-[4-(1,1-dimethylpropyl)phenyl]-2-methylpropyl]-2,6-dimethyl-, hydrochloride;Morpholine, 4-[3-[4-(1,1-dimethylpropyl)phenyl]-2-methylpropyl]-2,6-dimethyl-, hydrochloride (1:1)
CBNumber: CB1262395
Molecular Formula: C21H36ClNO
Formula Weight: 353.97
MOL File: 106614-68-0.mol

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Amorolfine hydrochloride Property

InChI: InChI=1/C21H35NO/c1-7-21(5,6)20-10-8-19(9-11-20)12-16(2)13-22-14-17(3)23-18(4)15-22/h8-11,16-18H,7,12-15H2,1-6H3/t16?,17-,18+
InChIKey: MQHLMHIZUIDKOO-AYHJJNSGNA-N
SMILES: C1(CC(C)CN2C[C@H](O[C@@H](C)C2)C)=CC=C(C(C)(C)CC)C=C1 |&1:7,9,r|
CAS DataBase Reference: 106614-68-0(CAS DataBase Reference)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: COS0000014
Product name: MORPHOLINE, 4-[3-[4-(1,1-DIMETHYLPROPYL)PHENYL]-2-METHYLPROPYL]-2,6-DIMETHYL HYDROCHLORIDE
Purity: 95.00%
Packaging: 100MG
Price: $160.65
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: COS0000014
Product name: MORPHOLINE, 4-[3-[4-(1,1-DIMETHYLPROPYL)PHENYL]-2-METHYLPROPYL]-2,6-DIMETHYL HYDROCHLORIDE
Purity: 95.00%
Packaging: 200MG
Price: $589.51
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: COS0000014
Product name: MORPHOLINE, 4-[3-[4-(1,1-DIMETHYLPROPYL)PHENYL]-2-METHYLPROPYL]-2,6-DIMETHYL HYDROCHLORIDE
Purity: 95.00%
Packaging: 1G
Price: $869.6
Updated: 2021/12/16

AHH

Product number: API-1216
Product name: Amorolfine Hydrochloride
Purity: 98%
Packaging: 0.1g
Price: $380
Updated: 2021/12/16

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Amorolfine hydrochloride Chemical Properties,Usage,Production

Uses

(Rac)-Amorolfine hydrochloride is the racemic form of Amorolfine hydrochloride. Amorolfine (Ro 14-4767/002) hydrochloride (HY-B0238) is an effective antifungal agent. Amorolfine hydrochloride inhibits the biosynthesis of ergosterol and has research potential for treating onychomycosis caused by Neoscytalidium dimidiatum[1][2].

Definition

ChEBI: Amorolfine hydrochloride is a hydrochloride resulting from the formal reacton of equimolar amounts of hydrogen chloride and amorolfine. An inhibitor of the action of squalene monooxygenase, Delta(14) reductase and D7-D8 isomerase and an antifungal agent, it is used for the topical treatment of fungal nail and skin infections. It has a role as an EC 1.14.13.132 (squalene monooxygenase) inhibitor, an EC 5.3.3.5 (cholestenol Delta-isomerase) inhibitor and an EC 1.3.1.70 (Delta(14)-sterol reductase) inhibitor. It is a hydrochloride and a morpholine antifungal drug. It contains an amorolfine(1+).

References

[1] Haria M, et al. Amorolfine. A review of its pharmacological properties and therapeutic potential in the treatment of onychomycosis and other superficial fungal infections. Drugs. 1995 Jan;49(1):103-20. DOI:10.2165/00003495-199549010-00008
[2] Bunyaratavej S, et al. Efficacy of 5% amorolfine nail lacquer in Neoscytalidium dimidiatum onychomycosis. J Dermatolog Treat. 2016 Aug;27(4):359-63. DOI:10.3109/09546634.2015.1109029

Amorolfine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Amorolfine hydrochloride Suppliers

China 43 Germany 1 India 2 United Kingdom 6 United States 11 Global 63

Heifei Yuanzhi Pharmaceutical R&D Co.,Ltd

Tel: 0551-68136310 18705595789
Fax: 0551-68136307
Email: 939249921@qq.com
Country: China
ProdList: 46
Advantage: 55

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15838
Advantage: 69

China Langchem Inc.

Tel: 0086-21-58956006
Fax: 0086-21-58956100
Country: China
ProdList: 7811
Advantage: 57

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66028182 18626450290
Email: yftan@aikonchem.com
Country: China
ProdList: 16679
Advantage: 50

Shanghai Qiao Chemical Science Co., Ltd

Tel: 021-58892003
Email: info@qiaochem.com
Country: China
ProdList: 6059
Advantage: 65

ShangHai Biochempartner Co.,Ltd

Tel: 177-54423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8000
Advantage: 62

Wuhan HongxinKang Fine Chemical Co., Ltd.

Tel: 027-59362599 18674037007
Fax: 027-84802889
Email: zhuoxingwc@163.com
Country: China
ProdList: 950
Advantage: 58

Wuhan FengyaoTonghui Chemical Products Co., Ltd.

Tel: 027-87466105 15377573527
Email: 2678564200@qq.com
Country: China
ProdList: 17987
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Nanjing crow LuNing pharmaceutical technology co., LTD

Tel: 13382066392
Country: CHINA
ProdList: 4877
Advantage: 58

Guangzhou Belka Biological Technology Co., Ltd.

Tel: +86-18665676617
Fax: 18665676617
Country: China
ProdList: 957
Advantage: 58

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View Lastest Price from Amorolfine hydrochloride manufacturers

Shaanxi Xianhe Biotech Co., Ltd

Product: Amorolfine hydrochloride 106614-68-0
Price: US $0.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 1000kg
Release date: 2025-04-30

BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.

Product: Amorolfine Hydrochloride 106614-68-0
Price: US $0.00/g
Min. Order: 1g
Purity: More Than 99%
Supply Ability: 100kg/Month
Release date: 2024-09-05

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AMOROLFINE HCL

(+/-)-cis-2,6-dimethyl-4-[2-methyl-3-(p-tert-pentylphenyl)propyl]morpholine hydrochloride

Morpholine, 4-[3-[4-(1,1-dimethylpropyl)phenyl]-2-methylpropyl]-2,6-dimethyl-, hydrochloride

Amorolfine hydrochloride

Morpholine, 4-[3-[4-(1,1-dimethylpropyl)phenyl]-2-methylpropyl]-2,6-dimethyl-, hydrochloride (1:1)

2,6-Dimethyl-4-(2-methyl-3-(4-(tert-pentyl)phenyl)propyl)morpholine hydrochloride

106614-68-0

C21H35NOHCl